Patents by Inventor Christopher K-H. Tseng

Christopher K-H. Tseng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2',3'-dideoxy-2'-fluoro-purine nucleosides and methods for using same
    Patent number: 5565437
    Abstract: Methods of treating a human infected with human immunodeficiency virus (HIV), such as a human with AIDS, with the purina nucleotides 2',3'-dideoxy-2'-beta-fluoroadenosine (FddA) and 2',3'-dideoxy-2'-beta-fluoroinosine (FddI) are disclosed. These nucleotides are stable in an acid environment and thus can be used for oral administration. Methods of inhibiting human immunodeficiency virus replication in a human T cell using these purina nucleotides are also disclosed.
    Type: Grant
    Filed: November 10, 1992
    Date of Patent: October 15, 1996
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Victor E. Marquez, John S. Driscoll, Christopher K-H. Tseng, James A. Kelley, David G. Johns, Hiroaki Mitsuya
  • Acid stable purine dideoxynucleosides
    Patent number: 5495010
    Abstract: Purine nucleosides active against human immunodeficiency virus which are substituted at the 2'-position by a strong electronegative group such as fluorine are stable in an acid environment and thus can be used for oral administration.
    Type: Grant
    Filed: September 19, 1991
    Date of Patent: February 27, 1996
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Victor E. Marquez, John S. Driscoll, Christopher K-H. Tseng, James A. Kelley, David G. Johns, Hiroaki Mitsuya
  • Lipophilic, aminohydrolase-activated prodrugs
    Patent number: 5459256
    Abstract: The present invention relates, in general, to prodrugs. In particular, the present invention relates to lipophilic, aminohydrolase-activated, anti-viral nucleoside prodrug compounds, pharmaceutical compositions containing these compounds, and methods of using these compounds.
    Type: Grant
    Filed: April 10, 1991
    Date of Patent: October 17, 1995
    Assignee: The Government of the United States of America as represented by the Department of Health and Human Services
    Inventors: Victor E. Marquez, John S. Driscoll, Harry Ford, Jr., James A. Kelley, Joseph J. Barchi, Jr., Hiroaki Mitsuya, Christopher K-H. Tseng, David G. Johns, Joseph E. Tomaszewski