Patents by Inventor Christopher K. Tuggle

Christopher K. Tuggle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9745561
    Abstract: The genetic basis for severe combined immunodeficiency disease (SCID) in pigs is described. In addition, tests for detecting pigs that are carriers for SCID or pigs with SCID are also described. Further, methods for producing pigs or herds of pigs with SCID are also described. Further, methods and compositions for treating, ameilioraing, inhibiting or correcting SCID are provided.
    Type: Grant
    Filed: January 8, 2015
    Date of Patent: August 29, 2017
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Jack C. M. Dekkers, Christopher K. Tuggle, Emily H. Waide, Jason W. Ross, N. Matthew Ellinwood, Martine Schroyen
  • Publication number: 20150216147
    Abstract: The genetic basis for severe combined immunodeficiency disease (SCID) in pigs is described. In addition, tests for detecting pigs that are carriers for SCID or pigs with SCID are also described. Further, methods for producing pigs or herds of pigs with SCID are also described. Further, methods and compositions for treating, ameilioraing, inhibiting or correcting SCID are provided.
    Type: Application
    Filed: January 8, 2015
    Publication date: August 6, 2015
    Inventors: Jack C.M. Dekkers, Christopher K. Tuggle, Emily H. Waide, Jason W. Ross, N. Matthew Ellinwood, Martine Schroyen
  • Patent number: 7081335
    Abstract: Disclosed herein are genetic markers for animal litter size, methods for identifying such markers, and methods of screening animals to determine those more likely to produce larger litters and preferably selecting those animals for future breeding purposes. The markers are based upon the presence or absence of certain polymorphisms in the prolactin receptor gene.
    Type: Grant
    Filed: July 6, 2001
    Date of Patent: July 25, 2006
    Assignees: Iowa State University Research Foundation, Inc., PIG Improvement Company UK Limited
    Inventors: Max F. Rothschild, Amy L. Vincent, Christopher K. Tuggle, Christy Gladney, Alan Mileham, Olwen Southwood, Graham Plastow, Carole Sargent
  • Patent number: 7070929
    Abstract: A method for determining improved disease resistance in animals is disclosed. The method assays for a novel genetic alleles of the BPI gene of the animal. The alleles are correlated with superior disease resistance. Novel nucleotide sequences, assays and primers are disclosed for the methods of the invention.
    Type: Grant
    Filed: May 31, 2002
    Date of Patent: July 4, 2006
    Assignees: Iowa State University Research Foundation, Inc., Pig Inprovement Company UK Limited, The United States of America as represented by the Secretary of Agriculture
    Inventors: Christopher K. Tuggle, Thomas J. Stabel, Xianwei Shi, Martha A. Mellencamp
  • Patent number: 6844159
    Abstract: A method for determining improved innate immunity, disease resistance or performance in animals is disclosed. The method involves assays for a genetic differences in the NRAMP1 gene of the animal which is associated with superior disease resistance. Novel NRAMP1 sequence, assays, and compositions for identifying the presence of absence of these alleles are provided.
    Type: Grant
    Filed: May 31, 2002
    Date of Patent: January 18, 2005
    Assignees: Iowa State University Research Foundation, Inc., Pig Inprovement Company UK Limited, The United States of America as represented by the Secretary of Agriculture
    Inventors: Christopher K. Tuggle, Lena Marklund, Thomas J. Stabel, Martha A. Mellencamp, Amber Stumbaugh
  • Publication number: 20040253594
    Abstract: A method for determining improved innate immunity, disease resistance or performance in animals is disclosed. The method involves assays for a genetic differences in the NRAMP1 gene of the animal which is associated with superior disease resistance. Novel NRAMP1 sequence, assays, and compositions for identifying the presence of absence of these alleles are provided.
    Type: Application
    Filed: July 15, 2004
    Publication date: December 16, 2004
    Inventors: Christopher K Tuggle, Lena Marklund, Thomas J Stabel, Martha A Mellencamp, Ambar Stumbaugh
  • Publication number: 20040234980
    Abstract: A method for determining improved disease resistance in animals is disclosed. The method assays for a novel genetic alleles of the BPI gene of the animal. The alleles are correlated with superior disease resistance. Novel nucleotide sequences, assays and primers are disclosed for the methods of the invention.
    Type: Application
    Filed: June 15, 2004
    Publication date: November 25, 2004
    Inventors: Christopher K. Tuggle, Thomas J. Stabel, Xianwei Shi, Martha A. Mellencamp
  • Publication number: 20030129609
    Abstract: A method for determining improved innate immunity, disease resistance or performance in animals is disclosed. The method involves assays for a genetic differences in the NRAMP1 gene of the animal which is associated with superior disease resistance. Novel NRAMP1 sequence, assays, and compositions for identifying the presence of absence of these alleles are provided.
    Type: Application
    Filed: May 31, 2002
    Publication date: July 10, 2003
    Inventors: Christopher K. Tuggle, Lena Marklund, Thomas J. Stabel, Martha A. Mellencamp, Amber Stumbaugh
  • Publication number: 20030104424
    Abstract: A method for determining improved disease resistance in animals is disclosed. The method assays for a novel genetic alleles of the BPI gene of the animal. The alleles are correlated with superior disease resistance. Novel nucleotide sequences, assays and primers are disclosed for the methods of the invention.
    Type: Application
    Filed: May 31, 2002
    Publication date: June 5, 2003
    Inventors: Christopher K. Tuggle, Thomas J. Stabel, Xianwei Shi, Martha A. Mellencamp
  • Publication number: 20020160372
    Abstract: Disclosed herein are genetic markers for animal litter size, methods for identifying such markers, and methods of screening animals to determine those more likely to produce larger litters and preferably selecting those animals for future breeding purposes. The markers are based upon the presence or absence of certain polymorphisms in the prolactin receptor gene.
    Type: Application
    Filed: July 6, 2001
    Publication date: October 31, 2002
    Inventors: Max F. Rothschild, Amy L. Vincent, Christopher K. Tuggle, Christy Gladney, Alan Mileham, Olwen Southwood, Graham Plastow, Carole Sargent
  • Patent number: 5939264
    Abstract: Disclosed herein are genetic markers for favorable reproductive traits in animals such as litter size, and weaning weight. Methods for identifying such markers, and methods of screening animals to determine those more likely to produce favorable reproductive traits and preferably selecting those animals for future breeding purposes.
    Type: Grant
    Filed: July 18, 1997
    Date of Patent: August 17, 1999
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Max F. Rothschild, Christopher K. Tuggle, Lori A. Messer, Tun-Ping Yu
  • Patent number: 5935784
    Abstract: Disclosed herein are genetic markers for pig litter size, methods for identifying such markers, and methods of screening pigs to determine those more likely to produce larger litters and preferably selecting those pigs for future breeding purposes. The markers are based upon the presence or absence of certain polymorphisms in the pig prolactin receptor gene.
    Type: Grant
    Filed: March 6, 1997
    Date of Patent: August 10, 1999
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Max F. Rothschild, Amy L. Vincent, Christopher K. Tuggle
  • Patent number: 5614364
    Abstract: Genetic markers in the bovine PIT-1 gene are disclosed which are associated with increased milk production and increased protein and fat content in cattle. Further, novel sequence data from intron regions of the gene are disclosed which may be used in a PCR test to screen for the presence of the marker.
    Type: Grant
    Filed: May 16, 1994
    Date of Patent: March 25, 1997
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Christopher K. Tuggle, Albert E. Freeman
  • Patent number: 5550024
    Abstract: Disclosed herein are genetic markers for pig litter size, methods for identifying such markers, and methods of screening pigs to determine those more likely to produce larger litters and preferably selecting those pigs for future breeding purposes based on the ESR polymorphisms. The markers are based upon the presence or absence of certain polymorphisms in the pig estrogen receptor gene. Preferably, the polymorphism is a restriction fragment length polymorphism (RFLP).
    Type: Grant
    Filed: September 26, 1994
    Date of Patent: August 27, 1996
    Assignees: Biotechnology Research & Development Corporation, Iowa State University Research Foundation, Inc.
    Inventors: Max F. Rothschild, Christopher K. Tuggle, Carol D. Jacobson, David A. Vaske, Alan J. Mileham, Graham S. Plastow