Abstract: A liquid heating appliance includes a liquid vessel and a power base configured to supply electrical power to the liquid vessel when the vessel is arranged thereon. The appliance further includes a user interface, for setting an operational mode of the liquid heating appliance. The user interface includes a rotatable ring which extends 360 degrees around the liquid heating appliance and a detection means configured to detect the position of the rotatable ring. The position of the rotatable ring determines the operational mode of the liquid heating appliance.

Abstract: A liquid heating appliance including a reservoir including a first and second chambers and a heating arrangement is provided. A mode valve is arranged to selectively allow liquid to flow between the first and second chambers. The appliance operates in a first mode in which the mode valve is closed and only liquid in the first chamber is heated and a second mode in which the mode valve is open and liquid in the first and second chambers is heated. A dispense outlet is moveable between a dispensing position and a non-dispensing position. The dispense outlet is mechanically coupled to the mode valve such that when the dispense outlet is moved into the dispense position, the mechanical coupling closes the mode valve and when the dispense outlet is moved into the non-dispensing position, the mechanical coupling opens the valve.

Abstract: Materials having the following structure (A) wherein R and R1 may be the same or different and each independently represents an alkyl or aryl group, X may be hydrogen or a C1 to C20 alkyl group which may be branched or linear and wherein the aromatic ring substituent joined to polymer B is positioned meta or para to the aromatic ring substituent joined to polymer A and, wherein polymer A is a non-polar polymer and polymer B is a polymer formed from at least two polar monomers, the materials are used to improve the adhesion of coatings such as paints, inks and adhesives to polyolefin substrates.

Abstract: The use of a block copolymer of the following structure. Wherein R and R1 may be the same or different and each independently represents an alkyl or aryl group, X may be hydrogen or C1 to C20 alkyl group which may be branched or linear and wherein the aromatic ring substituent joined to polymer B is positioned meta or para to the aromatic ring substituent joined to polymer A and, wherein polymer A is a polymer (or copolymer) of ethylene and polymer B is a polymer of monomers selected from vinyl acetate, C1-C9 acrylate esters, acrylic acid and mixtures thereof as an additive in polyethylene or polyethylene terephthalate to improve the adhesion between co-extruded layers of the polyethylene and the polyethylene terephthalate and laminated films derived from such use.

Abstract: A linear diblock copolymer of the general structure “Polymer A-linkage-Polymer B”, wherein Polymer A is essentially a nonpolar polymeric entity being a copolymer of propylene and ethylene, with propylene representing 51 to 99 weight percent of Polymer A; and Polymer B is a polymeric polar entity; and the use of said diblock copolymer to modify polymer bulk and interfacial properties in end applications as well as the intermediate material Polymer A-linkage useful in the manufacture of the diblock copolymer.

Abstract: A liquid heating appliance including a reservoir including a first and second chambers and a heating arrangement is provided. A mode valve is arranged to selectively allow liquid to flow between the first and second chambers. The appliance operates in a first mode in which the mode valve is closed and only liquid in the first chamber is heated and a second mode in which the mode valve is open and liquid in the first and second chambers is heated. A dispense outlet is moveable between a dispensing position and a non-dispensing position. The dispense outlet is mechanically coupled to the mode valve such that when the dispense outlet is moved into the dispense position, the mechanical coupling closes the mode valve and when the dispense outlet is moved into the non-dispensing position, the mechanical coupling opens the valve.

Abstract: The present invention relates to compositions and methods of use thereof for inhibiting mutant HTT mRNA transcription or CAG-expanded HTT protein expression in a cell, comprising contacting the cell with an effective amount of an oligomer targeting a differentiating polymorphism, wherein the differentiating polymorphism is selected from rs72239206, rs363107, rs362313, rs2530595, rs113407847. Specific oligomer sequences are also provided.

Abstract: The use of a block copolymer of the following structure. Wherein R and R1 may be the same or different and each independently represents an alkyl or aryl group, X may be hydrogen or C1 to C20 alkyl group which may be branched or linear and wherein the aromatic ring substituent joined to polymer B is positioned meta or para to the aromatic ring substituent joined to polymer A and, wherein polymer A is a polymer (or copolymer) of ethylene and polymer B is a polymer of monomers selected from vinyl acetate, C1-C9 acrylate esters, acrylic acid and mixtures thereof as an additive in polyethylene or polyethylene terephthalate to improve the adhesion between co-extruded layers of the polyethylene and the polyethylene terephthalate and laminated films derived from such use.

Abstract: The present invention relates to compositions and methods of use thereof for inhibiting mutant HTT mRNA transcription or CAG-expanded HTT protein expression in a cell, comprising contacting the cell with an effective amount of an oligomer targeting a differentiating polymorphism, wherein the differentiating polymorphism is selected from rs72239206, rs363107, rs362313, rs2530595, rs113407847. Specific oligomer sequences are also provided.

Abstract: The present invention relates to compositions and methods of use thereof for inhibiting mutant HTT mRNA transcription or CAG-expanded HTT protein expression in a cell, comprising contacting the cell with an effective amount of an oligomer targeting a differentiating polymorphism, wherein the differentiating polymorphism is selected from rs72239206, rs363107, rs362313, rs2530595, rs113407847. Specific oligomer sequences are also provided.

Abstract: The invention relates to electrochemical wound dressings wherein potential damage to healthy cells and granulating tissue induced by hypochlorite and/or hypochlorous acid is reduced by enabling effective removal or build-up of substantial concentrations thereof through use of catalysts and/or scavenging/sacrificing agents. In another aspect, the present invention relates to the use of the latter materials in medical devices and articles.

Abstract: The invention relates to electrochemical wound dressings wherein potential damage to healthy cells and granulating tissue induced by hypochlorite and/or hypochlorous acid is reduced by enabling effective removal or build-up of substantial concentrations thereof through use of catalysts and/or scavenging/sacrificing agents. In another aspect, the present invention relates to the use of the latter materials in medical devices and articles.

Abstract: Materials having structure (1), wherein R and R1 may be the same or different and each independently represents an alkyl or aryl group, X may be hydrogen or a C1 to C20 alkyl group which may be branched or linear and wherein the aromatic ring substituent joined to polymer B is positioned meta or para to the aromatic ring substituent joined to polymer A and, wherein polymer A is a non-polar polymer formed by metallocene catalysis and polymer B is a polymer formed by radical catalysis of a polar monomer are used as polymer additives particularly to improve the compatibility of mixtures of polymers.

Abstract: Materials having structure (1), wherein R and R1 may be the same or different and each independently represents an alkyl or aryl group, X may be hydrogen or a C1 to C20 alkyl group which may be branched or linear and wherein the aromatic ring substituent joined to polymer B is positioned meta or para to the aromatic ring substituent joined to polymer A and, wherein polymer A is a non-polar polymer formed by metallocene catalysis and polymer B is a polymer formed by radical catalysis of a polar monomer are used as polymer additives particularly to improve the compatibility of mixtures of polymers.

Abstract: The present invention relates to compositions and methods of use thereof for inhibiting mutant HTT mRNA transcription or CAG-expanded HTT protein expression in a cell, comprising contacting the cell with an effective amount of an oligomer targeting a differentiating polymorphism, wherein the differentiating polymorphism is selected from rs72239206, rs363107, rs362313, rs2530595, rs113407847. Specific oligomer sequences are also provided.

Abstract: Disclosed is a method and device to efficiently regulate flow of refrigerant while maintaining a sealed chamber in systems providing stored thermal energy for use during peak electrical demand. A mixed-phase regulator replaces the thermostatic expansion valve used in conventional air-conditioning systems that, along with capillary tubes and orifices, regulates the refrigerant fed from the compressor to the heat load.

Abstract: Disclosed is an efficient refrigeration apparatus that provides refrigerant based energy storage and cooling. When connected to a condensing unit, the system has the ability to store energy capacity during one time period and provide cooling from the stored energy during a second time period. The system requires minimal energy to operate during either time period, and only a fraction of the energy required to operate the system during the first time period is required to operate the system during the second time period using an optional refrigerant pump.