Abstract: Systems, devices, and methods for additive manufacturing of objects are provided. In some embodiments, a device for supporting an object during an additive manufacturing process includes a build platform having a surface, and a plurality of support structures extending above the surface of the build platform. Each support structure can be configured to couple to a portion of an additively manufactured object. The device can also include a plurality of actuators, each actuator being configured to adjust a position of a corresponding support structure relative to the build platform.

Abstract: Systems, methods, and computer-readable media are disclosed for using machine learning to generate automated custom media experiences. Example methods may include determining a first user identifier of a first user present in an environment, determining a first set of media preferences of the first user using media presented in association with the first user identifier, and determining a second user identifier of a second user present in the environment. Methods may include determining a second set of media preferences of the second user using media presented in association with the second user identifier, generating, using a first machine learning model, a first playlist of media using the first set of media preferences and the second set of media preferences for presentation to the first user and the second user, the first playlist comprising first media and second media, and causing audible presentation of the first media.

Abstract: The present disclosure provides platforms, systems, media, and methods for capturing clinical cases and expert-derived treatment rationales to facilitate biomedical decision making, which can include virtual clinical trials that continuously learn from the experiences of all patients, on all treatments, and all the time. Algorithms such as Bayesian machine learning methods can be applied to coordinate such virtual trials.

Abstract: A method of computational modeling to predict stability of a lyophilized drug product includes receiving model parameters describing a virtual cake, a virtual vial, a virtual stopper, and a virtual ambient environment. The method also includes computing, by implementing a computational model and at each of a plurality of virtual time steps, a change in water amount or concentration in the virtual cake, virtual air within the virtual vial, and the virtual stopper, in part by applying the model parameters to the computational model. The method also includes generating information for display to a user via a user interface.

Abstract: A method, system, and computer readable storage to enable a kiosk (or other interactive input/output device) in a building to allow a visitor to interact with it without physical contact (touching). The visitor can browse the tenant listing, request to visit a tenant of the building without an appointment, or visit a tenant in the building with an appointment. The visitor can use their own cell phone as an interface to interact with the kiosk and enable the functionality.

Abstract: A powered handheld electromechanical surgical device includes a motor configured to drive extension and retraction of a drive component, a sensor configured to sense force exerted on the drive component during extension of the drive component, and a controller including a processor and a non-transitory computer-readable storage medium storing instructions that, when executed by the processor, cause the processor to receive the sensed force from the sensor, control a speed of the motor during extension of the drive component in accordance with the sensed force, determine a speed profile or a force profile during extension of the drive component, and control a speed of the motor during retraction of the drive component in accordance with the speed profile or the force profile.

Abstract: A powered handheld electromechanical surgical device includes a motor configured to drive extension and retraction of a drive component, a sensor configured to sense force exerted on the drive component during extension of the drive component, and a controller including a processor and a non-transitory computer-readable storage medium storing instructions that, when executed by the processor, cause the processor to receive the sensed force from the sensor, control a speed of the motor during extension of the drive component in accordance with the sensed force, determine a speed profile or a force profile during extension of the drive component, and control a speed of the motor during retraction of the drive component in accordance with the speed profile or the force profile.

Abstract: A surgical instrument includes: an end effector; a power source; a motor coupled to the power source, the motor configured to actuate the end effector; and a controller operatively coupled to the motor and configured to control the motor based on a current draw of the motor and an angular velocity of the motor.

Abstract: A surgical access device including a cannula, a seal, and a seal guard is disclosed. The cannula includes a housing and an elongated portion extending distally from the housing. The seal is disposed at least partially within the housing of the cannula and includes an aperture for sealed reception of a surgical instrument therethrough. The seal guard is disposed at least partially within the housing of the cannula and proximally of the seal. The seal guard is formed from a flat sheet of material and folded into a funnel-like shape.

Abstract: A method is disclosed of processing a set of images. Each image in the set has an associated counterpart image. One or more regions of interest (ROIs) are identified in one or more of the images in the set of images. For ROI identified, a reference region is identified in the associated counterpart image. ROIs and associated reference regions are cropped out, thereby forming cropped pairs of images 1 . . . n1, that are fed to a deep learning model trained to make a prediction of probability of a state of the ROI, e.g., disease state, which generates a prediction Pi-, (i=1 . . . n) for each cropped pair. The model generates an overall prediction P from each of the predictions Pi. A visualization of the set of medical images and the associated counterpart images including the cropped pair of images is generated.

Abstract: Embodiments are directed to monitoring network traffic associated with networks to provide metrics. A monitoring engine may determine an anomaly based on the metrics exceeding threshold values. An inference engine may be instantiated to provide an anomaly profile based on portions of the network traffic that are associated with the anomaly. The inference engine may provide an investigation profile based on the anomaly profile such that the investigation profile includes information associated with investigation activities associated with an investigation of the anomaly. The inference engine may monitor the investigation of the anomaly based on other portions of the network traffic such that the other portions of the network traffic are associated with monitoring an occurrence of the investigation activities. The inference engine may modify a performance score associated with the investigation profile based on the occurrence of the investigation activities and a completion status of the investigation.

Abstract: A surgical stapling instrument includes a handle assembly, a surgical loading unit, and an adapter assembly interconnecting the handle assembly and the surgical loading unit. The surgical loading unit includes a memory having stored therein instructions, which when executed by a processor of the handle assembly, override instructions stored in a memory of the handle assembly and implement an operating parameter of the surgical loading unit that is unique to a tissue type or a specific surgical procedure to be performed by the surgical loading unit.

Abstract: A surgical access apparatus including a cannula defining an internal lumen, the cannula having a connection for receiving insufflation fluid. The apparatus also includes an obturator assembly, the obturator assembly configured to be inserted through a cannula so as to define an interstitial space between the cannula and the obturator assembly. The interstitial space is in fluid communication with the cannula connection so as to convey the insufflation fluid. The obturator assembly includes an obturator shaft having a hollow interior and a tip member at a distal end of the obturator shaft. The tip member is configured to penetrate and/or dissect through tissue. The tip member has an outer surface that defines a channel, the channel being in fluid communication with the interstitial space to as to convey the insufflation fluid from a proximal end of the tip member to a distal end of the tip member.

Abstract: Described herein is a mandibular repositioning device (MRD). The MRD includes an upper dental plate shaped to fit on a person's maxillary arch and a lower dental plate shaped to fit on the person's mandibular arch, the plates defining mating bite surfaces. The MRD includes a locating mechanism for effecting antero-posterior (AP) correction of the mandibular arch relative to the maxillary arch. The locating mechanism includes a locating formation extending from one of the upper dental plate and the lower dental plate, and a complementary receiving formation carried by the other of the upper dental plate and the lower dental plate. The receiving formation receives the locating formation for locating the plates relative to each other in a desired AP position of the mandibular arch relative to the maxillary arch. The MRD also includes a positioning element received at each molar region of at least one of the plates to alter the bite surface, thereby effecting a natural relative movement of the dental arches.

Abstract: A wearable, illuminating mask including a facepiece with slots located in side edges of the facepiece, wherein the facepiece is connected to bases of temples, wherein each base of temples includes a front and back cover that are attachable to one another. The front and back covers each include an inner wall portion, which portions each comprise a c-shaped support. These c-shaped supports extend towards each other when the front and back covers are connected together and form a cradle that align an LED with the slots of the facepiece, so as to illuminate the mask at specifically designed portions.

Abstract: Embodiments are directed to monitoring network traffic associated with networks to provide metrics. A monitoring engine may determine an anomaly based on the metrics exceeding threshold values. An inference engine may be instantiated to provide an anomaly profile based on portions of the network traffic that are associated with the anomaly. The inference engine may provide an investigation profile based on the anomaly profile such that the investigation profile includes information associated with investigation activities associated with an investigation of the anomaly. The inference engine may monitor the investigation of the anomaly based on other portions of the network traffic such that the other portions of the network traffic are associated with monitoring an occurrence of the investigation activities. The inference engine may modify a performance score associated with the investigation profile based on the occurrence of the investigation activities and a completion status of the investigation.