Abstract: A non-Cartesian coordinate positioning machine is provided that comprises an extendable leg assembly for positioning a component such as a measurement probe within a working volume of the machine, and a constraint member associated with the extendable leg assembly for providing a predetermined part of the extendable leg assembly with substantially a same orientation relative to gravity for a same position of the component within the working volume. In a preferred embodiment, the orientation relative to gravity is maintained substantially constant, so that a plane defined by the predetermined part is substantially aligned with gravity, as the component is moved around the working volume.

Abstract: The present invention provides methods for treating cancers having a mutation in one or more tumor suppressor genes, comprising providing to a subject in need thereof an inhibitor of a kinase, as well as related methods and compositions.

Abstract: A non-Cartesian coordinate positioning machine is provided that comprises an extendable leg assembly for positioning a component such as a measurement probe within a working volume of the machine, and a constraint member associated with the extendable leg assembly for providing a predetermined part of the extendable leg assembly with substantially a same orientation relative to gravity for a same position of the component within the working volume. In a preferred embodiment, the orientation relative to gravity is maintained substantially constant, so that a plane defined by the predetermined part is substantially aligned with gravity, as the component is moved around the working volume.

Abstract: A non-Cartesian coordinate positioning machine is provided that comprises an extendable leg assembly for positioning a component such as a measurement probe within a working volume of the machine, and a constraint member associated with the extendable leg assembly for providing a predetermined part of the extendable leg assembly with substantially a same orientation relative to gravity for a same position of the component within the working volume. In a preferred embodiment, the orientation relative to gravity is maintained substantially constant, so that a plane defined by the predetermined part is substantially aligned with gravity, as the component is moved around the working volume.

Abstract: The present invention provides methods for treating cancers having a mutation in one or more tumor suppressor genes, comprising providing to a subject in need thereof an inhibitor of a kinase, as well as related methods and compositions.

Abstract: A non-Cartesian coordinate positioning machine is provided that comprises an extendable leg assembly for positioning a component such as a measurement probe within a working volume of the machine, and a constraint member associated with the extendable leg assembly for providing a predetermined part of the extendable leg assembly with substantially a same orientation relative to gravity for a same position of the component within the working volume. In a preferred embodiment, the orientation relative to gravity is maintained substantially constant, so that a plane defined by the predetermined part is substantially aligned with gravity, as the component is moved around the working volume.

Abstract: Disclosed are systems, apparatus, and methods for identifying and visualizing duplicative records via a social network. In various implementations, a first data object may be created and stored in a first database system, where the first data object includes a plurality of data fields capable of storing a plurality of data values. In some implementations, a trigger function may be executed in response to creating the first data object, where the trigger function causes one or more servers in a second database system to determine if one or more existing data objects stored in the second database system include one or more data values that match data values included in the first data object. In various implementations, feed items may be generated in response to determining that a match exists, where the feed items provide one or more users with an indication of the determined match.

Abstract: Disclosed are systems, apparatus, and methods for identifying and processing duplicative records in one or more database systems. In various implementations, a first data object may be created and stored in a first database system, where the first data object includes a plurality of data fields capable of storing a plurality of data values. A trigger function may be executed in response to creating the first data object, where the trigger function causes one or more servers to determine if one or more existing data objects stored in the second database system match the first data object, and where the trigger function further causes one or more servers in the first database system to retrieve one or more data values from the one or more existing data objects. The retrieved one or more data values may be stored in one or more data fields of the first data object.

Abstract: The present invention provides methods for treating cancers having a mutation in one or more tumor suppressor genes, comprising providing to a subject in need thereof an inhibitor of a kinase, as well as related methods and compositions.

Abstract: A rotation detection kit, comprising: a beam source; a receiver comprising at least one beam intensity sensor; a polarizer device for location in the path of a beam emitted from the beam source and received by the beam sensor; and a modulator. The modulator is configured to modulate at least one of i) the beam source and ii) a beam emitted by the beam source to create a discretely varying polarization orientation thereby defining first and at least second temporally spaced beam portions. The temporally spaced beam portions are incident on the polarizer device and the beam sensor and have substantially identical profiles and at least an initial common propagation axis toward the polarizer device.

Abstract: A rotation detection kit, comprising a source for generating at least a first polarized beam emitted along a propagation axis, a receiver comprising at least a first beam intensity sensor and an analyzer. The analyzer comprises a first polarizer device for location in the at least first polarized beam between the source and at least first beam intensity sensor. The first polarizer device is configured such that the receiver can measure rotation between the source and the analyzer about a first axis that is non-parallel to the propagation axis based on the at least first beam intensity sensor's output.

Abstract: A rotation detection kit, comprising a source for generating at least a first polarized beam emitted along a propagation axis, a receiver comprising at least a first beam intensity sensor and an analyzer. The analyser comprises a first polarizer device for location in the at least first polarized beam between the source and at least first beam intensity sensor. The first polarizer device is configured such that the receiver can measure rotation between the source and the analyzer about a first axis that is non-parallel to the propagation axis based on the at least first beam intensity sensor's output.

Abstract: A rotation detection kit, comprising: a beam source; a receiver comprising at least one beam intensity sensor; a polariser device for location in the path of a beam emitted from the beam source and received by the beam sensor; and a modulator. The modulator is configured to modulate at least one of i) the beam source and ii) a beam emitted by the beam source to create a discretely varying polarisation orientation thereby defining first and at least second temporally spaced beam portions. The temporally spaced beam portions are incident on the polariser device and the beam sensor and have substantially identical profiles and at least an initial common propagation axis toward the polariser device.

Abstract: A method for identifying forms required for a business transaction and providing a packet containing the required forms to a requestor is provided. The method includes storing a set of rules in a first memory region accessible by a server, and storing for each of a plurality of tasks at least one address corresponding to at least one form associated with the task in a second memory region accessible by the server. A computer displays a user interface that prompts the requestor to provide answers to a sequence of questions. The sequence of questions is determined according to the set of rules, and at least one subsequent question of the sequence of questions is based on an answer to a previous question of the sequence of questions. The server determines a task being handled by the requester, based on the answers to the sequence of questions, and identifies a set of forms necessary for the determined task based on information stored in the second memory region.

Abstract: A method for the identification of peripheral equipment within a digital communication system, particularly a message switching system, having a central data processor as central controller and having a plurality of decentralized input/output processors equipped as subscriber and line sets with memory that control the peripheral equipment, the decentralized input/output processors being respectively in communication via a peripheral interface means with the central data processor. A set address (SA), a set type (ST) and an identifier of the memory capacity of the peripheral equipment are transmitted to the central data processor with the assistance of interface means (PBC), the central data processor subsequently transmitting a set-associated memory load information as memory load call signal via the data bus (DBUS) to the interface means (PBC) and, thus, to the memory (SRM).