Patents by Inventor Christopher Krause

Christopher Krause has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240118209
    Abstract: A method is proposed for detecting at least one fluorescence pattern on an immunofluorescence image of a biological cell substrate, comprising the following steps: incubating the cell substrate with a liquid patient sample, which potentially includes primary antibodies, and furthermore with secondary antibodies, which are marked using a fluorescence stain, irradiating the cell substrate using excitation radiation and capturing the immunofluorescence image, determining segmentation information comprising at least one first and one second segmentation area, wherein the segmentation areas each represent a respective cell substrate area, via segmentation of the immunofluorescence image using a first neural network, determining a boundary area, which represents a transition from the first cell substrate area towards the second cell substrate area in the fluorescence image, on the basis of the segmentation information, selecting multiple partial images from the immunofluorescence image along the boundary area, dete
    Type: Application
    Filed: September 29, 2023
    Publication date: April 11, 2024
    Applicant: EUROIMMUN Medizinische Labordiagnostika AG
    Inventors: Jens Hocke, Jens Krauth, Stefan Gerlach, Christopher Krause, Melanie Hahn, Jörn Voigt, Enno SCHMIDT, Nina VAN BEEK
  • Publication number: 20240119589
    Abstract: A method is proposed for detecting a presence of a fluorescence pattern on an immunofluorescence image of a biological cell substrate, comprising the following steps: incubating the cell substrate with a liquid patient sample, which potentially comprises primary antibodies, and furthermore with secondary antibodies, which are marked using a fluorescence stain, irradiating the cell substrate using excitation radiation and capturing the immunofluorescence image, determining respective items of location information, which indicate respective locations of respective relevant subsections of the cell substrate in the fluorescence image, and determining respective first partial confidence measures of respective presences of the fluorescence pattern on the respective subsections by means of a first neural network on the basis of the overall fluorescence image, extracting respective image subsections, which correspond to the respective subsections of the cell substrate, from the fluorescence image on the basis of the
    Type: Application
    Filed: September 22, 2023
    Publication date: April 11, 2024
    Applicant: EUROIMMUN Medizinische Labordiagnostika AG
    Inventors: Jens KRAUTH, Jens HOCKE, Stefan GERLACH, Christopher KRAUSE, Melanie HAHN, Jörn VOIGT
  • Patent number: 11898625
    Abstract: A stator assembly for a torque converter includes a body, a one-way clutch, and a washer. The body is rotatable about an axis and has a cavity defined by an axial wall radially spaced from the axis and a radial wall extending radially inward from the axial wall. The one-way clutch is disposed in the cavity. The washer includes a thrust surface, a supporting surface, and an axial retention feature. The thrust surface faces away from the cavity. The supporting surface directly contacts the one-way clutch. The axial retention element is configured to connect to the axial wall of the body.
    Type: Grant
    Filed: January 12, 2023
    Date of Patent: February 13, 2024
    Assignee: Schaeffler Technologies AG & Co. KG
    Inventors: Alexander Reimchen, Christopher Krause
  • Publication number: 20240036226
    Abstract: Fluid detection systems and methods using the same are disclosed. In embodiments the fluid detection systems include a sensor module and an electronics module. The sensor module includes a sensor housing that includes a liquid flow path and a sensor element disposed around at least part of the liquid flow path. The sensor element can detect a capacitance of the liquid flow path and provide a sensor signal to a controller in the electronics module. The electronics module can determine a detected capacitance in the liquid flow path based at least in part on the sensor signal, and can determine whether a wet event has occurred based on a comparison of the detected capacitance to a threshold capacitance. Methods using the fluid detection systems and fluid supply systems including the fluid detection systems are also disclosed.
    Type: Application
    Filed: December 8, 2021
    Publication date: February 1, 2024
    Applicant: WATTS REGULATOR CO.
    Inventors: STEVEN CASTRIGNO, JAMES ERHARDT, CHRISTOPHER KRAUSE
  • Publication number: 20230071078
    Abstract: There is proposed a method for detecting a presence of a fluorescence pattern type on an organ segment via immunofluorescence microscopy and digital image processing. The steps comprise: provision of the organ segment, incubation of the organ segment with a liquid patient sample, incubation of the organ segment with secondary antibodies which have been labelled with a fluorescent dye, acquisition of a fluorescence image of the organ segment in a colour channel corresponding to the fluorescent dye, and provision of the fluorescence image to a neural network. What takes place by means of the neural network is simultaneous determination of segmentation information through segmentation of the fluorescence image and, furthermore, of a measure of confidence indicating an actual presence of the fluorescence pattern type.
    Type: Application
    Filed: August 25, 2022
    Publication date: March 9, 2023
    Applicant: EUROIMMUN Medizinische Labordiagnostika AG
    Inventors: Stefan GERLACH, Jens KRAUTH, Christian MARZAHL, Christopher KRAUSE, Jens HOCKE, Maick DANCKWARDT, Melanie HAHN, Jörn VOIGT
  • Publication number: 20220404283
    Abstract: A method for detecting at least one potential presence of at least one fluorescence pattern type on an organ section by means of immunofluorescence microscopy and by means of digital image processing is disclosed. An organ section is provided on a slide and the section is incubated with a liquid patient sample which potentially includes primary antibodies and with secondary antibodies which have been labelled with a fluorescent dye. A fluorescence image of the organ section is acquired. A determination is made, by segmentation of the fluorescence image by means of a first neural network, of a sub-area of the fluorescence image that is relevant to formation of the fluorescence pattern type. A determination is made, on the basis of the fluorescence image by means of a second neural network, of the measure of confidence that indicates an actual presence of the fluorescence pattern type.
    Type: Application
    Filed: December 21, 2021
    Publication date: December 22, 2022
    Applicant: EUROIMMUN Medizinische Labordiagnostika AG
    Inventors: Jens Krauth, Stefan Gerlach, Christian Marzahl, Christopher Krause, Jens Hocke, Melanie Hahn, Joern Voigt
  • Publication number: 20220228989
    Abstract: A method and apparatus are provided for detecting respective potential presences of respective different cellular fluorescence pattern types on a biological cellular substrate including human epithelioma cells (HEp cells), wherein the fluorescence pattern types include different antinuclear antibody fluorescence pattern types. A method is also provided for detecting potential presences of different cellular fluorescence pattern types on a biological cellular substrate including human epithelioma cells by means of digital image processing, as well as a computing unit, a data network device, a computer program product and a data carrier signal therefor.
    Type: Application
    Filed: January 19, 2022
    Publication date: July 21, 2022
    Applicant: EUROIMMUN Medizinische Labordiagnostika AG
    Inventors: Christopher Krause, Jens Krauth, Stefan Gerlach, Christian Marzahl, Melanie Hahn, Joern Voigt
  • Publication number: 20220196553
    Abstract: A method for detecting at least one potential presence of at least one fluorescence pattern type on an organ section by means of immunofluorescence microscopy and by means of digital image processing is disclosed. An organ section is provided on a slide and the section is incubated with a liquid patient sample which potentially includes primary antibodies and with secondary antibodies which have been labelled with a fluorescent dye. A fluorescence image of the organ section is acquired. A determination is made, by segmentation of the fluorescence image by means of a first neural network, of a sub-area of the fluorescence image that is relevant to formation of the fluorescence pattern type. A determination is made, on the basis of the fluorescence image by means of a second neural network, of the measure of confidence that indicates an actual presence of the fluorescence pattern type.
    Type: Application
    Filed: December 21, 2021
    Publication date: June 23, 2022
    Applicant: EUROIMMUN Medizinische Labordiagnostika AG
    Inventors: Jens Krauth, Stefan Gerlach, Christian Marzahl, Christopher Krause, Jens Hocke, Melanie Hahn, Joern Voigt
  • Patent number: 11367187
    Abstract: A method is for detecting respective potential presence of respective different antinuclear antibody fluorescence pattern types on a biological cell substrate including human epithelioma cells, including: acquiring a first image which represents staining of the cell substrate by a first fluorescent dye, and acquiring a second image which represents staining of the cell substrate by a second fluorescent dye, detecting, on the basis of the first image, respective image segments which in each case represent at least one mitotic cell, selecting, on the basis of the detected image segments, subimages of the first image and subimages corresponding thereto of the second image and detecting, on the basis of the selected subimages of the first image and of the selected subimages of the second image, respective actual presence of respective cellular fluorescence pattern types by means of a convolutional neural network.
    Type: Grant
    Filed: July 2, 2020
    Date of Patent: June 21, 2022
    Assignee: EUROIMMUN Medizinische Labordiagnostika AG
    Inventors: Jens Krauth, Christopher Krause, Joern Voigt, Melanie Hahn, Christian Marzahl, Stefan Gerlach
  • Publication number: 20220082567
    Abstract: There is proposed a method for detecting a binding of autoantibodies from a patient sample to double-stranded deoxyribonucleic acid using Crithidia luciliae cells by means of fluorescence microscopy, including the steps of: provision of a substrate which has multiple Crithidia luciliae cells, incubation of the substrate with the patient sample which potentially has the autoantibodies, incubation of the substrate with secondary antibodies which have each been labelled with a preferably green fluorescent dye, acquisition of a fluorescence image of the substrate, identification by means of a first pretrained convolutional neural network of respective sub-images in the one fluorescence image that each represent a Crithidia luciliae cell, furthermore respective processing of at least one subset of the respective sub-images by means of a second pretrained convolutional neural network for determining respective binding measures which indicate a respective extent of a binding of autoantibodies in a respective kinetop
    Type: Application
    Filed: September 17, 2021
    Publication date: March 17, 2022
    Applicant: EUROIMMUN Medizinische Labordiagnostika AG
    Inventors: Stefan Gerlach, Jens Krauth, Christian Marzahl, Christopher Krause, Maick Danckwardt, Melanie Hahn, Jörn Voigt
  • Patent number: 11181176
    Abstract: A turbine assembly includes a turbine shell, turbine hub, and a thrust washer. The turbine hub is coupled to the turbine shell via a fastener. The thrust washer is disposed on the turbine hub and includes at least one tab configured to contact the fastener. The fastener axially and radially retains the thrust washer on the turbine hub.
    Type: Grant
    Filed: February 19, 2020
    Date of Patent: November 23, 2021
    Assignee: Schaeffler Technologies AG & Co. KG
    Inventors: Scott Angel, Christopher Krause
  • Publication number: 20210019883
    Abstract: A method is for detecting respective potential presence of respective different antinuclear antibody fluorescence pattern types on a biological cell substrate including human epithelioma cells, including: acquiring a first image which represents staining of the cell substrate by a first fluorescent dye, and acquiring a second image which represents staining of the cell substrate by a second fluorescent dye, detecting, on the basis of the first image, respective image segments which in each case represent at least one mitotic cell, selecting, on the basis of the detected image segments, subimages of the first image and subimages corresponding thereto of the second image and detecting, on the basis of the selected subimages of the first image and of the selected subimages of the second image, respective actual presence of respective cellular fluorescence pattern types by means of a convolutional neural network.
    Type: Application
    Filed: July 2, 2020
    Publication date: January 21, 2021
    Applicant: EUROIMMUN Medizinische Labordiagnostika AG
    Inventors: Jens KRAUTH, Christopher Krause, Joern Voigt, Melanie Hahn, Christian Marzahl, Stefan Gerlach
  • Publication number: 20200263774
    Abstract: A turbine assembly includes a turbine shell, turbine hub, and a thrust washer. The turbine hub is coupled to the turbine shell via a fastener. The thrust washer is disposed on the turbine hub and includes at least one tab configured to contact the fastener. The fastener axially and radially retains the thrust washer on the turbine hub.
    Type: Application
    Filed: February 19, 2020
    Publication date: August 20, 2020
    Applicant: Schaeffler Technologies AG & Co. KG
    Inventors: Scott Angel, Christopher Krause
  • Patent number: 10711873
    Abstract: A hydrodynamic side plate for a stator in a torque converter includes a first radial surface, a second radial surface opposite the first radial surface, a first axial restriction surface on the first radial surface opposite an inner race of a stator assembly, a second axial restriction surface on the first radial surface opposite locking components of the stator assembly, and a plurality of hydrodynamic pads in the second radial surface separated by a plurality of corresponding radial grooves. The first axial restriction surface is configured to restrict axial movement of the inner race of the stator assembly. The second axial restriction surface is configured to restrict axial movement of the locking components of the stator assembly. The second radial surface comprises at least two anti-rotation tabs configured to prevent relative motion with the stator assembly.
    Type: Grant
    Filed: June 19, 2018
    Date of Patent: July 14, 2020
    Assignee: SCHAEFFLER TECHNOLOGIES AG & CO. KG
    Inventors: Christopher Krause, Nigel Gurney, Scott Strong
  • Publication number: 20190383375
    Abstract: A hydrodynamic side plate for a stator in a torque converter includes a first radial surface, a second radial surface opposite the first radial surface, a first axial restriction surface on the first radial surface opposite an inner race of a stator assembly, a second axial restriction surface on the first radial surface opposite locking components of the stator assembly, and a plurality of hydrodynamic pads in the second radial surface separated by a plurality of corresponding radial grooves. The first axial restriction surface is configured to restrict axial movement of the inner race of the stator assembly. The second axial restriction surface is configured to restrict axial movement of the locking components of the stator assembly. The second radial surface comprises at least two anti-rotation tabs configured to prevent relative motion with the stator assembly.
    Type: Application
    Filed: June 19, 2018
    Publication date: December 19, 2019
    Inventors: Christopher Krause, Nigel Gurney, Scott Strong
  • Publication number: 20180291989
    Abstract: A torque converter including a cover for receiving torque from a prime mover, an impeller fixed to the cover to form a housing of the torque converter, a turbine disposed in the housing for receiving torque from the impeller, a stator disposed in the housing for multiplying the torque and a one-way clutch connected to the stator. A side plate is connected to the one-way clutch, the side plate having a sealing surface that is in contact with a seal that seals the side plate to a turbine hub.
    Type: Application
    Filed: April 10, 2017
    Publication date: October 11, 2018
    Applicant: Schaeffler Technologies AG & Co. KG
    Inventors: Christopher Krause, Carleton Caldwell, Adam Saleh
  • Patent number: 9559614
    Abstract: A grid-connected inverter for feeding current via a transformer into an electric power grid includes an output bridge arrangement that is actuated via a pulse width modulator, wherein a periodic auxiliary signal is used to determine switching times of the output bridge arrangement. The inverter also includes a synchronization unit for phase synchronization of the auxiliary signal with the electric power grid, wherein the synchronization unit is configured to set a predetermined phase offset (??0) of the periodic auxiliary signal with respect to a phase of the electric power grid.
    Type: Grant
    Filed: September 13, 2013
    Date of Patent: January 31, 2017
    Assignee: SMA SOLAR TECHNOLOGY AG
    Inventors: Thomas Eberhardt, Josef Petschenka, Christopher Krause, Christian Landau
  • Patent number: D774187
    Type: Grant
    Filed: April 8, 2014
    Date of Patent: December 13, 2016
    Assignee: The Procter & Gamble Company
    Inventors: Lisa June Hood, James Christopher Krause, Brian Patrick Bjelovuk, Glen Ray Lash, Megan M. Meyerrenke
  • Patent number: D857884
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: August 27, 2019
    Assignee: The Procter & Gamble Company
    Inventors: Lisa June Hood, James Christopher Krause, Brian Patrick Bjelovuk, Glen Ray Lash, Megan M. Meyerrenke
  • Patent number: D1010111
    Type: Grant
    Filed: July 2, 2019
    Date of Patent: January 2, 2024
    Assignee: The Procter and Gamble Company
    Inventors: Lisa June Hood, James Christopher Krause, Brian Patrick Bjelovuk, Glen Ray Lash, Megan M. Meyerrenke