Abstract: Systems and methods for managing computer-assisted communications channels based on relationships between users who wish to communicate with one another are described. The relationship-managed communications system allows users to retain control over whom they permit to communicate with them and under what conditions such communications may take place, for example when they take place and/or using which communications channels, by allowing pairs of users to establish relationships which specify communications permissions. Users of the system provide their contact information to the relationship-managed communications system, and the system uses the securely stored information to mediate the establishment of communications channels between users. Embodiments of the system may intelligently route communications to substitute channels based on relationship-related and other information.