Patents by Inventor Christopher L. Corless

Christopher L. Corless has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110171216
    Abstract: Isolated monoclonal antibodies are disclosed herein that specifically bind a cell surface antigen expressed on the human pancreatic cancer cells or precancerous pancreatic cancer cells. Humanized forms of these antibodies, functional fragments of these antibodies, and hybridomas producing these antibodies are also disclosed. The antibodies can be conjugated to an effector molecule, such as a detectable marker, a therapeutic agent, or a toxin. The antibodies can be used for in vitro or in vivo pancreatic cancer diagnosis or disease monitoring via detection of pancreatic cancer cells or the pancreatic cancer cell surface antigen. Methods of treating a pancreatic cancer by administration of the antibodies are also disclosed.
    Type: Application
    Filed: September 9, 2009
    Publication date: July 14, 2011
    Inventors: Phillip R. Streeter, Markus Grompe, Karin M. Hardiman, Brett C. Sheppard, Christopher L. Corless, Terry K. Morgan
  • Publication number: 20090221601
    Abstract: The invention described herein relates to methods of identifying and treating individuals with protein tyrosine kinase associated disorders that have, or may, become resistant to treatment with a kinase inhibitor such as imatinib due to a gain-of-function mutation in KIT tyrosine kinase.
    Type: Application
    Filed: June 9, 2006
    Publication date: September 3, 2009
    Inventors: Francis Y. Lee, Michael C. Heinrich, Christopher L. Corless