Patents by Inventor Christopher L. Kepley

Christopher L. Kepley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140161733
    Abstract: A composition comprising: a liposome having a bilayer structure, a gadofullerene having a high relaxivity, and an amphiphilic receptor ligand. In the composition, the gadofullerene is embedded in the bilayer structure of the liposome. In addition, a method for detecting atherosclerotic plaque in an animal using the composition is described.
    Type: Application
    Filed: March 29, 2012
    Publication date: June 12, 2014
    Applicant: LUNA INNOVATIONS INCORPORATED
    Inventors: Zhiguo Zhou, Robert P. Lenk, Christopher L. Kepley
  • Patent number: 8680125
    Abstract: Described herein are methods for treating inflammatory disorders. The methods comprise administering to a subject in need thereof a therapeutically effective amount of a synthetically modified fullerene.
    Type: Grant
    Filed: March 3, 2009
    Date of Patent: March 25, 2014
    Assignee: Luna Innovations Incorporated
    Inventors: Christopher L. Kepley, Robert P. Lenk, Stephen R. Wilson, Zhiguo Zhou, Darren K. MacFarland
  • Patent number: 8563585
    Abstract: Described herein are methods for treating inflammatory disorders. The methods comprise administering to a subject in need thereof a therapeutically effective amount of a synthetically modified fullerene.
    Type: Grant
    Filed: March 3, 2009
    Date of Patent: October 22, 2013
    Assignee: Luna Innovations, Incorporated
    Inventors: Christopher L. Kepley, Robert P. Lenk, Stephen R. Wilson, Zhiguo Zhou, Darren K. MacFarland
  • Publication number: 20110251158
    Abstract: Described herein are methods for treating inflammatory disorders or for inhibiting the build-up of arterial plaque. The methods comprise administering to a subject in need thereof a therapeutically effective amount of a synthetically modified fullerene.
    Type: Application
    Filed: September 16, 2010
    Publication date: October 13, 2011
    Applicant: Luna Innovations Incorporated
    Inventors: Christopher L. KEPLEY, Robert P. LENK, Darren K. MACFARLAND, Zhiguo ZHOU
  • Publication number: 20110190251
    Abstract: Disclosed herein are methods of inhibiting the build-up of arterial plaque in a subject in need thereof. These methods comprise administering to the subject in need thereof a therapeutically effective amount of fullerenes.
    Type: Application
    Filed: March 3, 2009
    Publication date: August 4, 2011
    Inventors: Christopher L. Kepley, Robert P. Lenk, Stephen R. Wilson, Zhiguo Zhou
  • Publication number: 20110028522
    Abstract: Described herein are methods for treating inflammatory disorders. The methods comprise administering to a subject in need thereof a therapeutically effective amount of a synthetically modified fullerene.
    Type: Application
    Filed: March 3, 2009
    Publication date: February 3, 2011
    Applicant: LUNA INNOVATIONS INCORPORATED
    Inventors: Christopher L. Kepley, Robert P. Lenk, Stephen R. Wilson, Zhiguo Zhou, Darren K. MacFarland
  • Publication number: 20110021630
    Abstract: Disclosed herein are methods for treating wounds. In one embodiment, the method comprises: administering to a subject in need thereof a therapeutically effective amount of a synthetically modified fullerene of the formula Zm—F—Yn wherein F is a fullerene of formula Cp or X@Cp, the fullerene having two opposing poles and an equatorial region; Cp represents a fullerene cage having p carbon atoms, and X@CP represents such a fullerene cage having a chemical group X within the cage; Z and Y are positioned near respective opposite poles of Cp; m=1-5 and Z is a hydrophilic, lipophilic, or amphiphilic chemical moiety; n=1-5 and Y is a lipophilic chemical moiety; p=60-200 and p is an even number; and X, if present, represents one or more metal atoms within the fullerene (F), optionally in the form of a trinitride of formula Gi=1?3Hk=3?iN in which G and H are metal atoms.
    Type: Application
    Filed: March 3, 2009
    Publication date: January 27, 2011
    Inventors: Christopher L. Kepley, Robert P. Lenk, Stephen R. Wilson, Zhiguo Zhou
  • Publication number: 20110003773
    Abstract: Described herein are methods for treating lack of hair growth or a reduction or loss of existing hair by stimulating and/or restoring hair growth, or preventing hair loss. The methods comprise administering to a subject in need thereof a therapeutically effective amount of a fullerene.
    Type: Application
    Filed: March 3, 2009
    Publication date: January 6, 2011
    Applicant: Luna Innovations Incorporated
    Inventors: Christopher L. Kepley, Robert P. Lenk, Stephen R. Wilson, Zhiguo Zhou