Patents by Inventor CHRISTOPHER L. RIFE

CHRISTOPHER L. RIFE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PAENIBACILLUS AND BACILLUS SPP. MANNANASES
    Publication number: 20180320158
    Abstract: Disclosed herein are mannanases from Paenibacillus or Bacillus spp, polynucleotides encoding the mannanases, compositions containing the mannanases, and methods of use thereof. Compositions containing mannanases are suitable for use as detergents and for cleaning fabrics and hard surfaces, as well as in a variety of other industrial applications.
    Type: Application
    Filed: November 7, 2016
    Publication date: November 8, 2018
    Inventors: Kai Bao, Carol Marie Fioresi, Dina Finan, Christian D. Adams, Viktor Yuryevich Alekseyev, Richard R. Bott, Christopher L. Rife
  • AMYLASE WITH MALTOGENIC PROPERTIES
    Publication number: 20180112203
    Abstract: The present teachings provide an amylase with maltogenic properties. Nucleic acids encoding the maltogenic amylase and variants thereof, expression vectors, formulations, and host cells are also provided. Additional embodiments of the present teachings provide various methods of use and methods of manufacturing.
    Type: Application
    Filed: November 15, 2013
    Publication date: April 26, 2018
    Applicant: DANISCO US INC.
    Inventors: RICHARD R. BOTT, LING HUA, ZHEN QIAN, CHRISTOPHER L. RIFE, JAYARAMA K. SHETTY, ZHONGMEI TANG, ZHEYONG YU, BO ZHANG
  • Isoprene synthase variants for improved production of isoprene
    Patent number: 9273298
    Abstract: The present invention provides methods and compositions comprising at least one isoprene synthase enzyme with improved specific productivity. In particular, the present invention provides variant plant isoprene synthases for increased isoprene production in host cells.
    Type: Grant
    Filed: October 27, 2011
    Date of Patent: March 1, 2016
    Assignees: DANISCO US INC., THE GOODYEAR TIRE & RUBBER COMPANY
    Inventors: Zachary Q. Beck, David A. Estell, Jeffrey V. Miller, Christopher L. Rife, Derek H. Wells
  • Isoprene synthase variants with improved solubility for production of isoprene
    Patent number: 9273299
    Abstract: The present invention provides methods and compositions of variant polypeptides having isoprene synthase activity with improved solubility. In particular, the present invention provides isoprene synthase variant for increased isoprene production in recombinant host cells.
    Type: Grant
    Filed: April 11, 2014
    Date of Patent: March 1, 2016
    Assignees: DANISCO US INC., THE GOODYEAR & TIRE RUBBER COMPANY
    Inventors: Christopher L. Rife, Derek H. Wells
  • Three-dimensional structure of isoprene synthase and its use thereof for generating variants
    Patent number: 9175313
    Abstract: The present invention provides a three-dimensional structures of P. tremuloides isoprene synthase and P. alba isoprene synthase. The invention also provides methods of using the three-dimensional structure to design isoprene synthases with improved activity for increased isoprene production in microbial host cells. Biosynthetically produced isoprene of the present invention finds use in the manufacture of rubber and elastomers.
    Type: Grant
    Filed: May 6, 2013
    Date of Patent: November 3, 2015
    Assignees: Danisco US Inc., The Goodyear Tire & Rubber Company
    Inventors: Zachary Q. Beck, Richard R. Bott, Jeffrey V. Miller, Christopher L. Rife, Derek H. Wells
  • Identification of isoprene synthase variants with improved properties for the production of isoprene
    Patent number: 9163263
    Abstract: The invention provides for compositions and methods for producing isoprene using isoprene synthase variants with improved properties.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: October 20, 2015
    Assignees: The Goodyear Tire & Rubber Company, Danisco US Inc.
    Inventors: Zachary Q. Beck, David A. Estell, Jeffrey V. Miller, James Ngai, Christopher L. Rife, Derek H. Wells
  • ISOPRENE SYNTHASE VARIANTS FOR IMPROVED MICROBIAL PRODUCTION OF ISOPRENE
    Publication number: 20150191712
    Abstract: The present invention provides methods and compositions comprising at least one isoprene synthase enzyme with improved catalytic activity and/or solubility. In particular, the present invention provides variant plant isoprene synthases for increased isoprene production in microbial host cells. Biosynthetically produced isoprene of the present invention finds use in the manufacture of rubber and elastomers.
    Type: Application
    Filed: November 17, 2014
    Publication date: July 9, 2015
    Inventors: Richard R. BOTT, Marguerite A. Cervin, James T. Kellis, JR., Joseph C. Mcauliffe, Andrei Miasnikov, Caroline M. Peres, Christopher L. Rife, Derek H. Wells, Walter Weyler, Gregory M. Whited
  • Legume isoprene synthase for production of isoprene
    Patent number: 8895277
    Abstract: The present invention provides methods and compositions of polypeptides having isoprene synthase activity with improved performance characteristics. In particular, the present invention provides legume isoprene synthases for increased isoprene production in recombinant host cells.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: November 25, 2014
    Assignees: Danisco US Inc., The Goodyear Tire & Rubber Company
    Inventors: Mary K. Beatty, Kevin Hayes, Zhenglin Hou, David J. Meyer, Kishore Nannapaneni, Christopher L. Rife, Derek H. Wells, Gina M. Zastrow-Hayes
  • ISOPRENE SYNTHASE VARIANTS WITH IMPROVED SOLUBILITY FOR PRODUCTION OF ISOPRENE
    Publication number: 20140315275
    Abstract: The present invention provides methods and compositions of variant polypeptides having isoprene synthase activity with improved solubility. In particular, the present invention provides isoprene synthase variant for increased isoprene production in recombinant host cells.
    Type: Application
    Filed: April 11, 2014
    Publication date: October 23, 2014
    Applicants: THE GOODYEAR TIRE & RUBBER COMPANY, DANISCO US INC.
    Inventors: Christopher L. RIFE, Derek H. WELLS
  • Isoprene synthase variants with improved solubility for production of isoprene
    Patent number: 8735134
    Abstract: The present invention provides methods and compositions of variant polypeptides having isoprene synthase activity with improved solubility. In particular, the present invention provides isoprene synthase variant for increased isoprene production in recombinant host cells.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: May 27, 2014
    Assignees: Danisco US Inc., The Goodyear Tire & Rubber Company
    Inventors: Christopher L. Rife, Derek H. Wells
  • IDENTIFICATION OF ISOPRENE SYNTHASE VARIANTS WITH IMPROVED PROPERTIES FOR THE PRODUCTION OF ISOPRENE
    Publication number: 20130330796
    Abstract: The invention provides for compositions and methods for producing isoprene using isoprene synthase variants with improved properties.
    Type: Application
    Filed: March 13, 2013
    Publication date: December 12, 2013
    Applicants: The Goodyear Tire & Rubber Company, DANISCO US INC.
    Inventors: Zachary Q. BECK, David A. ESTELL, Jeffrey V. MILLER, James NGAI, Christopher L. RIFE, Derek H. WELLS
  • LEGUME ISOPRENE SYNTHASE FOR PRODUCTION OF ISOPRENE
    Publication number: 20130330709
    Abstract: The present invention provides methods and compositions of polypeptides having isoprene synthase activity with improved performance characteristics. In particular, the present invention provides legume isoprene synthases for increased isoprene production in recombinant host cells.
    Type: Application
    Filed: March 13, 2013
    Publication date: December 12, 2013
    Applicants: The Goodyear Tire & Rubber Company, Danisco US Inc.
    Inventors: Mary K. BEATTY, Kevin HAYES, Zhenglin HOU, David J. MEYER, Kishore NANNAPANENI, Christopher L. RIFE, Derek H. WELLS, Gina M. ZASTROW-HAYES
  • ISOPRENE SYNTHASE VARIANTS WITH IMPROVED SOLUBILITY FOR PRODUCTION OF ISOPRENE
    Publication number: 20130295632
    Abstract: The present invention provides methods and compositions of variant polypeptides having isoprene synthase activity with improved solubility. In particular, the present invention provides isoprene synthase variant for increased isoprene production in recombinant host cells.
    Type: Application
    Filed: October 26, 2012
    Publication date: November 7, 2013
    Applicants: The Goodyear Tire & Rubber Company, Danisco US Inc.
    Inventors: Christopher L. RIFE, Derek H. WELLS
  • THREE-DIMENSIONAL STRUCTURE OF ISOPRENE SYNTHASE AND ITS USE THEREOF FOR GENERATING VARIANTS
    Publication number: 20130252303
    Abstract: The present invention provides a three-dimensional structures of P. tremuloides isoprene synthase and P. alba isoprene synthase. The invention also provides methods of using the three-dimensional structure to design isoprene synthases with improved activity for increased isoprene production in microbial host cells. Biosynthetically produced isoprene of the present invention finds use in the manufacture of rubber and elastomers.
    Type: Application
    Filed: May 6, 2013
    Publication date: September 26, 2013
    Applicants: THE GOODYEAR TIRE & RUBBER COMPANY, DANISCO US INC.
    Inventors: Zachary Q. BECK, Richard R. BOTT, Jeffrey V. MILLER, Christopher L. RIFE, Derek H. WELLS
  • ISOPRENE SYNTHASE VARIANTS FOR IMPROVED PRODUCTION OF ISOPRENE
    Publication number: 20130045891
    Abstract: The present invention provides methods and compositions comprising at least one isoprene synthase enzyme with improved specific productivity. In particular, the present invention provides variant plant isoprene synthases for increased isoprene production in host cells.
    Type: Application
    Filed: October 27, 2011
    Publication date: February 21, 2013
    Inventors: ZACHARY Q. BECK, DAVID A. ESTELL, JEFFREY V. MILLER, CHRISTOPHER L. RIFE, DEREK H. WELLS