Abstract: The present invention relates to IKK-alpha inhibitory compounds, or a pharmaceutically acceptable salts, hydrates or solvates thereof, having the structural Formula (I), shown below: wherein R1, X, R3 R4 and X1 are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which IKK-alpha activity is implicated.

Abstract: A system-in-package cellular assembly is disclosed. The assembly may include a main board including a multi-layer printed circuit board. The main board may include one or more through holes and be detachably connectable to an end-product via the one or more through holes and one or more connecting members. The main board may be reversibly, electrically couplable to the end-product via the one or more through holes and the one or more connecting members. The assembly may include an add-on board including one or more through holes and be detachably connectable to the main board via one or more connectors. The add-on board may be reversibly, electrically couplable to the main board via one or more main board surface mount connectors and one or more add-on board surface mount connectors. The add-on board may include at least one of one or more sensors or one or more sensor through holes.

Abstract: A system-in-package cellular assembly is disclosed. The assembly may include a main board including a multi-layer printed circuit board. The main board may include one or more through holes and be detachably connectable to an end-product via the one or more through holes and one or more connecting members. The main board may be reversibly, electrically couplable to the end-product via the one or more through holes and the one or more connecting members. The assembly may include an add-on board including one or more through holes and be detachably connectable to the main board via one or more connectors. The add-on board may be reversibly, electrically couplable to the main board via one or more main board surface mount connectors and one or more add-on board surface mount connectors. The add-on board may include at least one of one or more sensors or one or more sensor through holes.

Abstract: A modular shelter structure is an apparatus that provides readily available housing for a variety of environments. The apparatus includes a shelter, a plurality of first locking mechanisms, and a plurality of second locking mechanisms. The shelter includes a floor base, a plurality of portable walls, and at least one roof panel. The floor base balances the shelter across various terrains. The plurality of portable walls surrounds the floor base and defines an interior environment with the floor base. The interior environment is enclosed with the at least one roof panel. The plurality of portable walls is attached onto the floor base with the plurality of first locking mechanisms. Similarly, the plurality of portable walls is attached onto the roof panel with the plurality of second locking mechanisms. The plurality of first locking mechanisms and the plurality of second locking mechanisms each include an inner tube and an outer sleeve.

Abstract: A turbine spirometer comprises a breathing tube into which is subject is to breath and a vane to be driven by the subject's breath. The breathing tube has a first axis A-A at its opening in the direction of air flow and the vane rotates about a second axis B-B. The first A-A and second B-B axes are inclined to one another at angle of around 100 degrees such that in use the axis of rotation B-B is substantially vertical.

Abstract: The invention pertains to steroid modified solatrioses and the synthesis thereof as well as to intermediate compounds useful for the synthesis of the steroid modified solatrioses.

Abstract: The invention pertains to steroid modified solatrioses and the synthesis thereof as well as to intermediate compounds useful for the synthesis of the steroid modified solatrioses.

Abstract: The present invention relates to steroid modified chacotrioses and the synthesis thereof as well as to intermediate compounds useful for the synthesis of the steroid modified chacotrioses and solatrioses. Moreover, the present inventions relates to a method for the preparation of steroid-modified solatrioses.

Abstract: Apparatus (2) for measuring carbon monoxide on a person's breath, which apparatus (2) comprises measuring means (4) for measuring the carbon monoxide on the person's breath, and message giving means (6) for giving a message which is in a language and which is appropriate to the amount of the carbon monoxide measured on the person's breath.