Abstract: PYY analogs are disclosed that include modifications that increase half-life when compared to native, human PYY, as well as additional modifications that increase potency and selectivity to the NPY2 receptor. Pharmaceutical compositions also are disclosed that include one or more of the PYY analogs described herein in a pharmaceutically acceptable carrier. Methods of making and using the PYY analogs also are disclosed, especially for treating obesity and obesity-related diseases and disorders such as type II diabetes mellitus.

Abstract: A DC link capacitor (8) comprises a capacitor housing, a plurality of capacitor cells (1), each comprising a film capacitor element (2) with a wound metallized film and two contact terminals (3a, 3b) connected to the metallized plastic film. The plurality of capacitor cells (1) are arranged in the capacitor housing (4) and are sealed therein by means of a sealing material (7). The contact terminals (3a, 3b) are electrically isolated from each other and protrude separately out of the sealing material (7), in order to be connected by means of bus bars.

Abstract: PYY analogs are disclosed that include modifications that increase half-life when compared to native, human PYY, as well as additional modifications that increase potency and selectivity to the NPY2 receptor. Pharmaceutical compositions also are disclosed that include one or more of the PYY analogs described herein in a pharmaceutically acceptable carrier. Methods of making and using the PYY analogs also are disclosed, especially for treating obesity and obesity-related diseases and disorders such as type II diabetes mellitus.

Abstract: PYY analogs are disclosed that include modifications that increase half-life when compared to native, human PYY, as well as additional modifications that increase potency and selectivity to the NPY2 receptor. Pharmaceutical compositions also are disclosed that include one or more of the PYY analogs described herein in a pharmaceutically acceptable carrier. Methods of making and using the PYY analogs also are disclosed, especially for treating obesity and obesity-related diseases and disorders such as type II diabetes mellitus.

Abstract: The invention concerns a magnetic core device (1) to be used in a power converter (100), comprising at least one fixation leg (7), and a body (51) comprising a magnetic core (3). The at least one fixation leg (7) extends from the body (51), and is configured to firmly fixate the magnetic core device (1) to a target component (110) such as a housing (110) of the power converter (100). The at least one fixation leg (7) and the body (51) are integrally formed as one-piece.

Abstract: PYY analogs are disclosed that include modifications that increase half-life when compared to native, human PYY, as well as additional modifications that increase potency and selectivity to the NPY2 receptor. Pharmaceutical compositions also are disclosed that include one or more of the PYY analogs described herein in a pharmaceutically acceptable carrier. Methods of making and using the PYY analogs also are disclosed, especially for treating obesity and obesity-related diseases and disorders such as type II diabetes mellitus.

Abstract: PYY analogs are disclosed that include modifications that increase half-life when compared to native, human PYY, as well as additional modifications that increase potency and selectivity to the NPY2 receptor. Pharmaceutical compositions also are disclosed that include one or more of the PYY analogs described herein in a pharmaceutically acceptable carrier. Methods of making and using the PYY analogs also are disclosed, especially for treating obesity and obesity-related diseases and disorders such as type II diabetes mellitus.

Abstract: PYY analogs are disclosed that include modifications that increase half-life when compared to native, human PYY, as well as additional modifications that increase potency and selectivity to the NPY2 receptor. Pharmaceutical compositions also are disclosed that include one or more of the PYY analogs described herein in a pharmaceutically acceptable carrier. Methods of making and using the PYY analogs also are disclosed, especially for treating obesity and obesity-related diseases and disorders such as type II diabetes mellitus.

Abstract: Method for securing a sensor (1) to a support (2), the support (2) comprising a receiving zone (16) for the sensor (1) and a crimping zone (17), the sensor (1) comprising a housing (20) provided with a projecting zone (25), wherein, in said method:—the sensor (1) is moved next to the receiving zone (16) of the support (2) and brought into contact with all or part thereof, and—all or part of the crimping zone (17) is deformed such that said portion(s) of the crimping zone (17) that is/are deformed in this way press(es) against all or part of the projection zone (25) so as to keep the sensor (1) in position with respect to the support (2).