Patents by Inventor Christopher Lowe

Christopher Lowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzofuran-4-carboxamides and their therapeutic use
    Patent number: 6066657
    Abstract: A compound of formula (i) ##STR1## has therapeutic utility via inhibition of phosphodiesterase and THF release.
    Type: Grant
    Filed: February 9, 1999
    Date of Patent: May 23, 2000
    Assignee: Darwin Discovery, Ltd.
    Inventors: Hazel Joan Dyke, John Gary Montana, Christopher Lowe, Karen Ann Runcie, Alan Findlay Haughan, Verity Margaret Sabin, Duncan Hannah, Louise Picken, Andrew Sharpe
  • Process for making fluorinated polymer adsorbent particles
    Patent number: 6046246
    Abstract: Chemically resistant, strong fluorinated copolymer adsorbent particles for use in carrying out chromatographic separations are prepared by high shear, anaerobic reaction of a di-unsaturated crosslinking agent with a polyfluorinated monomer in the presence of poly(vinyl alcohol) and a porogen.
    Type: Grant
    Filed: June 10, 1999
    Date of Patent: April 4, 2000
    Assignee: ProMetic Biosciences, Inc.
    Inventors: Christopher Lowe, Julie Tucker
  • Benzofuran carboxamides and their therapeutic use
    Patent number: 5925636
    Abstract: Compounds having the formula (i), ##STR1## wherein the groups R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are defined herein. The compounds of the present invention can be utilized to treat disease states capable of being modulated by inhibition of proteins which mediate cellular activity, such as tumor necrosis factor (TNF) and/or phosphodiesterase IV (PDE IV).
    Type: Grant
    Filed: May 20, 1997
    Date of Patent: July 20, 1999
    Assignee: Darwin Discovery Limited
    Inventors: Hazel Joan Dyke, Christopher Lowe, John Gary Montana
  • Quinoline carboxanides and their therapeutic use
    Patent number: 5804588
    Abstract: The subject invention concerns novel compounds of the general formula (i) ##STR1## that are useful in treating disease states, such as those states associated with proteins that mediate cellular activity. The compounds of the subject invention can be used, for example, to inhibit tumor necrosis factor and/or phosphodiesterase IV, The subject invention also concerns methods for treating disease states using the compounds of the invention.
    Type: Grant
    Filed: May 20, 1997
    Date of Patent: September 8, 1998
    Assignee: Chiroscience Limited
    Inventors: Hazel Joan Dyke, John Gary Montana, Christopher Lowe, Hannah Jayne Kendall, Verity Margaret Sabin
  • Benzofuran sulphonanmides
    Patent number: 5773467
    Abstract: Benzofuran carboxides and sulphonamides have therapeutic utility, e.g. in the treatment of inflammation and asthma, by virtue of their ability to inhibit phosphodiesterases and tumor necrosis factor.
    Type: Grant
    Filed: December 5, 1996
    Date of Patent: June 30, 1998
    Assignee: Chiroscience, Ltd.
    Inventors: Hazel Joan Dyke, Hannah Jayne Kendall, Christopher Lowe, John Gary Montana
  • 3,4-disubstituted-phenylsulphonamides and their therapeutic use
    Patent number: 5728712
    Abstract: 3,4-Disubstituted-phenylsulphonamides have therapeutic utility via TNF or phosphodiesterase inhibition.
    Type: Grant
    Filed: May 20, 1996
    Date of Patent: March 17, 1998
    Assignee: Chiroscience Limited
    Inventors: John Gary Montana, Hazel Joan Dyke, Robert James Maxey, Christopher Lowe
  • Chromatographic separation device
    Patent number: 4891120
    Abstract: A chromatographic separation device comprises a body 2 of a semiconductor material which body has a longitudinal channel 1 formed in a surface thereof, the channel 1 being capable of containing a predetermined volume of a liquid or solid material for a chromatography test or separation procedure, the channel carrying at least one electrode 6 positioned intermediate the channel ends. The semiconductor body may additionally support an electronic or optical sensor 8 arranged in line with said channel 1 to provide an integrated detection system.
    Type: Grant
    Filed: April 12, 1988
    Date of Patent: January 2, 1990
    Inventors: Rajinder S. Sethi, Jack Brettle, Christopher Lowe