Patents by Inventor Christopher M. Colangelo

Christopher M. Colangelo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7335762
    Abstract: Disclosed herein are methods and apparatuses for sequencing a nucleic acid. These methods permit a very large number of independent sequencing reactions to be arrayed in parallel, permitting simultaneous sequencing of a very large number (>10,000) of different oligonucleotides.
    Type: Grant
    Filed: August 15, 2002
    Date of Patent: February 26, 2008
    Assignee: 454 Life Sciences Corporation
    Inventors: Jonathan M. Rothberg, Joel S. Bader, Scott B. Dewell, Keith McDade, John W. Simpson, Jan Berka, Christopher M. Colangelo, Michael P. Weiner
  • Patent number: 7264929
    Abstract: Disclosed herein are methods and apparatuses for sequencing a nucleic acid. These methods permit a very large number of independent sequencing reactions to be arrayed in parallel, permitting simultaneous sequencing of a very large number (>10,000) of different oligonucleotides.
    Type: Grant
    Filed: November 19, 2002
    Date of Patent: September 4, 2007
    Assignee: 454 Life Sciences Corporation
    Inventors: Jonathan M. Rothberg, Joel S. Bader, Scott B. Dewell, Keith McDade, John W. Simpson, Jan Berka, Christopher M. Colangelo
  • Patent number: 7244559
    Abstract: Disclosed herein are methods and apparatuses for sequencing a nucleic acid. These methods permit a very large number of independent sequencing reactions to be arrayed in parallel, permitting simultaneous sequencing of a very large number (>10,000) of different oligonucleotides.
    Type: Grant
    Filed: March 21, 2001
    Date of Patent: July 17, 2007
    Assignee: 454 Life Sciences Corporation
    Inventors: Jonathan M. Rothberg, Joel S. Bader, Scott B. Dewell, Keith McDade, John W. Simpson, Jan Berka, Christopher M. Colangelo
  • Patent number: 7211390
    Abstract: Disclosed herein are methods and apparatuses for sequencing a nucleic acid. In one aspect, the method includes annealing a population of circular nucleic acid molecules to a plurality of anchor primers linked to a solid support, and amplifying those members of the population of circular nucleic acid molecules which anneal to the target nucleic acid, and then sequencing the amplified molecules by detecting the presence of a sequence byproduct such as pyrophosphate.
    Type: Grant
    Filed: February 26, 2004
    Date of Patent: May 1, 2007
    Assignee: 454 Life Sciences Corporation
    Inventors: Jonathan M. Rothberg, Joel S. Bader, Scott B. Dewell, Keith McDade, John W. Simpson, Jan Berka, Christopher M. Colangelo
  • Publication number: 20040248161
    Abstract: Disclosed herein are methods and apparatuses for sequencing a nucleic acid. In one aspect, the method includes annealing a population of circular nucleic acid molecules to a plurality of anchor primers linked to a solid support, and amplifying those members of the population of circular nucleic acid molecules which anneal to the target nucleic acid, and then sequencing the amplified molecules by detecting the presence of a sequence byproduct such as pyrophosphate.
    Type: Application
    Filed: February 26, 2004
    Publication date: December 9, 2004
    Inventors: Jonathan M. Rothberg, Joel S. Bader, Scott B. Dewell, Keith McDade, John W. Simpson, Jan Berka, Christopher M. Colangelo
  • Publication number: 20030148344
    Abstract: Disclosed herein are methods and apparatuses for sequencing a nucleic acid. These methods permit a very large number of independent sequencing reactions to be arrayed in parallel, permitting simultaneous sequencing of a very large number (>10,000) of different oligonucleotides.
    Type: Application
    Filed: November 19, 2002
    Publication date: August 7, 2003
    Inventors: Jonathan M. Rothberg, Joel S. Bader, Scott B. Dewell, Keith McDade, John W. Simpson, Jan Berka, Christopher M. Colangelo
  • Publication number: 20030104421
    Abstract: A plurality of oligonucleotides are provided having use in the amplification of target nucleic acid sequences. The oligonucleotides are used in simultaneous amplification of a multiplicity of nucleic acid sequences, providing a more balanced amplification of all target sequences. The oligonucleotides also provides a reaction system for the amplification of nucleic acid targets, and provide a method for selectively detecting one or more target nucleic acid sequences in a population of nucleic acid molecules, as well as a method for detecting a single nucleotide polymorphism in a population of nucleic acid molecules.
    Type: Application
    Filed: May 7, 2002
    Publication date: June 5, 2003
    Inventors: Christopher M. Colangelo, Jan Fredik Simons, Kendra Swirsding
  • Publication number: 20030100102
    Abstract: Disclosed herein are methods and apparatuses for sequencing a nucleic acid. These methods permit a very large number of independent sequencing reactions to be arrayed in parallel, permitting simultaneous sequencing of a very large number (>10,000) of different oligonucleotides.
    Type: Application
    Filed: August 15, 2002
    Publication date: May 29, 2003
    Inventors: Jonathan M. Rothberg, Joel S. Bader, Scott B. Dewell, Keith McDade, John W. Simpson, Jan Berka, Christopher M. Colangelo, Michael P. Weiner
  • Publication number: 20030068629
    Abstract: Disclosed herein are methods and apparatuses for sequencing a nucleic acid. These methods permit a very large number of independent sequencing reactions to be arrayed in parallel, permitting simultaneous sequencing of a very large number (>10,000) of different oligonucleotides.
    Type: Application
    Filed: March 21, 2002
    Publication date: April 10, 2003
    Inventors: Jonathan M. Rothberg, Joel S. Bader, Scott B. Dewell, Keith McDade, John W. Simpson, Jan Berka, Christopher M. Colangelo, Michael P. Weiner
  • Publication number: 20020012930
    Abstract: Disclosed herein are methods and apparatuses for sequencing a nucleic acid. These methods permit a very large number of independent sequencing reactions to be arrayed in parallel, permitting simultaneous sequencing of a very large number (>10,000) of different oligonucleotides.
    Type: Application
    Filed: March 21, 2001
    Publication date: January 31, 2002
    Inventors: Jonathan M. Rothberg, Joel S. Bader, Scott B. Dewell, Keith McDade, John W. Simpson, Jan Berka, Christopher M. Colangelo