Patents by Inventor Christopher M. Hine

Christopher M. Hine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rad51 derived cancer cell specific promoters for targeted anti-cancer therapy
    Patent number: 8188252
    Abstract: Provided are compositions and methods for inhibiting growth of cancer cells. The method of the invention relates to delivering to cells an effective amount of a composition that contains a polynucleotide having a Rad51 promoter or a polynucleotide having at least 95% similarity to a Rad51 promoter. The Rad51 promoter is operably linked to a coding region for a cytotoxic agent. In vitro and in vivo results demonstrating effectiveness of the polynucleotides of the invention are presented.
    Type: Grant
    Filed: November 17, 2009
    Date of Patent: May 29, 2012
    Assignee: University of Rochester
    Inventors: Christopher M. Hine, Andrei Seluanov, Vera Gorbunova
  • RAD51 DERIVED CANCER CELL SPECIFIC PROMOTERS FOR TARGETED ANTI- CANCER THERAPY
    Publication number: 20100130596
    Abstract: Provided are compositions and methods for inhibiting growth of cancer cells. The method of the invention relates to delivering to cells an effective amount of a composition that contains a polynucleotide having a Rad51 promoter or a polynucleotide having at least 95% similarity to a Rad51 promoter. The Rad51 promoter is operably linked to a coding region for a cytotoxic agent. In vitro and in vivo results demonstrating effectiveness of the polynucleotides of the invention are presented.
    Type: Application
    Filed: November 17, 2009
    Publication date: May 27, 2010
    Inventors: Christopher M. Hine, Andrei Seluanov, Vera Gorbunova