Patents by Inventor Christopher M. O'Connor

Christopher M. O'Connor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BISPHOSPHONATE COMPOSITIONS AND METHODS FOR TREATING HEART FAILURE
    Publication number: 20180125869
    Abstract: The present invention provides for methods and compositions for treating and/or preventing cardiac dysfunction by administering to subject a therapeutically effective amount of a bisphosphonate, functional analogue or a pharmaceutically effective salt thereof.
    Type: Application
    Filed: January 8, 2018
    Publication date: May 10, 2018
    Inventors: KENNETH W. LYLES, CATHLEEN S. COLON-EMERIC, CHRISTOPHER M. O'CONNOR, RICHARD S. STACK, COLLEEN STACK
  • Bisphosphonate compositions and methods for treating and\or reducing cardiac dysfunction
    Patent number: 9949992
    Abstract: The present invention provides for methods and compositions for treating, reducing and/or preventing cardiac dysfunction by administering to subject a therapeutically effective amount of a bisphosphonate, prodrug thereof, functional analog or a pharmaceutically effective salt thereof in an amount sufficient to increase activity of at least one kinase in heart tissue of the subject.
    Type: Grant
    Filed: November 14, 2012
    Date of Patent: April 24, 2018
    Assignee: DUKE UNIVERSITY
    Inventors: Kenneth W. Lyles, Cathleen S. Colon-Emeric, Christopher M. O'Connor, Dennis Abraham, Kent Nilsson, Howard Rockman, Graham Russell
  • Methods for treating heart failure using bisphosphonate compositions
    Patent number: 9867838
    Abstract: The present invention provides for methods for treating and/or reducing cardiac dysfunction by administering to subject a therapeutically effective amount of a bisphosphonate, functional analogue or a pharmaceutically effective salt thereof.
    Type: Grant
    Filed: September 1, 2010
    Date of Patent: January 16, 2018
    Assignee: DUKE UNIVERSITY
    Inventors: Kenneth W. Lyles, Cathleen S. Colon-Emeric, Christopher M. O'Connor, Richard S. Stack, Colleen Stack
  • BISPHOSPHONATE COMPOSITIONS AND METHODS FOR TREATING AND\OR REDUCING CARDIAC DYSFUNCTION
    Publication number: 20140296166
    Abstract: The present invention provides for methods and compositions for treating, reducing and/or preventing cardiac dysfunction by administering to subject a therapeutically effective amount of a bisphosphonate, prodrug thereof, functional analogue or a pharmaceutically effective salt thereof in an amount sufficient to increase activity of at least one kinase in heart tissue of the subject.
    Type: Application
    Filed: November 14, 2012
    Publication date: October 2, 2014
    Inventors: Kenneth W. Lyles, Cathleen S. Colon-Emeric, Christopher M. O'Connor, Dennis Abraham, Kent Nilson, Howard Rockman, Graham Russell
  • BISPHOSPHONATE COMPOSITIONS AND METHODS FOR TREATING HEART FAILURE
    Publication number: 20120208786
    Abstract: The present invention provides for methods and compositions for treating and/or preventing cardiac dysfunction by administering to subject a therapeutically effective amount of a bisphosphonate, functional analogue or a pharmaceutically effective salt thereof.
    Type: Application
    Filed: September 1, 2010
    Publication date: August 16, 2012
    Inventors: Kenneth W. Lyles, Cathleen S. Colon-Emeric, Christopher M. O'Connor, Richard S. Stack, Colleen Stack
  • Methods of inhibiting platelet activation with selective serotonin reuptake inhibitors
    Patent number: 6552014
    Abstract: The present invention pertains to methods for reducing the platelet activation state in an individual comprising administering a selective serotonin reuptake inhibitor (SSRI). The platelet activation state is reduced upon administering a SSRI, as measured by one or more platelet activation markers. The invention also relates to methods for treating or preventing an individual at risk for a vascular event, disease or disorder by administering a SSRI.
    Type: Grant
    Filed: March 12, 2001
    Date of Patent: April 22, 2003
    Assignee: HeartDrug Research, L.L.C.
    Inventors: Victor L. Serebruany, Paul A. Gurbel, Christopher M. O'Connor
  • Methods of inhibiting platelet activation with selective serotonin reuptake inhibitors
    Publication number: 20020013343
    Abstract: The present invention pertains to methods for reducing the platelet activation state in an individual comprising administering a selective serotonin reuptake inhibitor (SSRI). The platelet activation state is reduced upon administering a SSRI, as measured by one or more platelet activation markers. The invention also relates to methods for treating or preventing an individual at risk for a vascular event, disease or disorder by administering a SSRI.
    Type: Application
    Filed: March 12, 2001
    Publication date: January 31, 2002
    Inventors: Victor L. Serebruany, Paul A. Gurbel, Christopher M. O' Connor
  • Methods of inhibiting platelet activation with selective serotonin reuptake inhibitors
    Patent number: 6245782
    Abstract: The present invention pertains to methods for reducing the platelet activation state in an individual comprising administering a selective serotonin reuptake inhibitor (SSRI). The platelet activation state is reduced upon administering a SSRI, as measured by one or more platelet activation markers. The invention also relates to methods for treating or preventing an individual at risk for a vascular event, disease or disorder by administering a SSRI.
    Type: Grant
    Filed: May 17, 1999
    Date of Patent: June 12, 2001
    Assignee: Heartdrug Research L.L.C.
    Inventors: Victor L. Serebruany, Paul A. Gurbel, Christopher M. O'Connor