Abstract: Provided herein are methods of monitoring for the production of select antibodies in a non-human animal, comprising (a) immunizing a non-human animal with an immunogen; (b) obtaining a blood sample comprising antibody secreting cells (ASCs) from said non-human animal; and (c) individually assaying ASCs present in the blood sample, or a fraction thereof, for the production of select antibodies. Methods of guiding antibody production in a non-human animal for the production of select antibodies are also provided. In exemplary embodiments, the method comprises performing a cycle of (a) to (c), as above, and repeating the cycle when the percentage of ASCs producing select antibodies is below a threshold. In various aspects, the cycle is repeated until the percentage of ASCs producing select antibodies is at or above a threshold. Single cell assays are further provided herein.

Abstract: Methods and apparatuses to assist a user in the performance of a plurality of tasks are provided. The method may comprise storing at least one care plan in a voice assistant, the care plan defining a plurality of tasks to be performed, capturing speech input from the user, determining, from the speech input, a selected interaction with a care plan, and in response to the selected interaction, providing a speech dialog with the user reflective of the care plan. Alternatively, the method may comprise capturing speech input from a user, determining from the speech input, a first weight associated with a resident, associating the first weight with a care plan in turn associated with the resident, comparing the first weight to a second weight associated with the resident and the care plan, and providing a speech dialog regarding reweighting the resident based on the comparison.

Abstract: Methods and apparatuses to assist a user in the performance of a plurality of tasks are provided. The method may comprise storing at least one care plan in a voice assistant, the care plan defining a plurality of tasks to be performed, capturing speech input from the user, determining, from the speech input, a selected interaction with a care plan, and in response to the selected interaction, providing a speech dialog with the user reflective of the care plan. Alternatively, the method may comprise capturing speech input from a user, determining from the speech input, a first weight associated with a resident, associating the first weight with a care plan in turn associated with the resident, comparing the first weight to a second weight associated with the resident and the care plan, and providing a speech dialog regarding reweighting the resident based on the comparison.