Abstract: The present invention provides mutant RSV F molecules, such as those that can be, or are stabilized, in a pre-fusion conformation by the introduction of one or more DT cross-links. The present invention also provides methods of making such mutant RSV F molecules, compositions comprising such mutant RSV F molecules, and methods of use of such mutant RSV F molecules, for example in vaccination methods, therapeutic methods, and antibody production methods.

Abstract: A system and method in accordance with example embodiments may include systems and methods for generating and transforming data presentation. The method may include receiving, using a processor, a request for a web page, and submitting, by the processor, the request to a computer server system. The request can include a user identification and a user password. The method may further include receiving, from the computer server system, data corresponding to the requested web page. Further, the method includes storing, in a memory, the received data, and causing the received data to be shown on a display associated with the user device.

Abstract: A method and apparatus are provided for estimating characteristic differences between wireless signals transmitted from the same location in spaced apart frequency ranges. Also provided are a method and apparatus for estimating a combined time of arrival of the wireless signals, using the characteristic differences. A further method is provided, for identifying that two signals have been transmitted from the same location. Also disclosed is a method of maintaining a database of characteristic difference information.

Abstract: The present invention provides mutant RSV F molecules, such as those that can be, or are stabilized, in a pre-fusion conformation by the introduction of one or more DT cross-links. The present invention also provides methods of making such mutant RSV F molecules, compositions comprising such mutant RSV F molecules, and methods of use of such mutant RSV F molecules, for example in vaccination methods, therapeutic methods, and antibody production methods.

Abstract: Disclosed herein are compositions for vaccination against respiratory syncytial virus (RSV) comprising a RSV F polypeptide stabilized in a prefusion conformation and an inulin adjuvant. Also disclosed herein are methods of vaccinating a subject against a respiratory syncytial virus (RSV) infection comprising administering to the subject an RSV F polypeptide stabilized in a prefusion conformation and an inulin adjuvant. In some embodiments, the subject is a female, and the method can reduce RSV infection in the subject and/or in the offspring of the subject. In some embodiments, the method decreases vaccine-enhanced respiratory disease (VERD) and/or eosinophilia in the subject or offspring of the subject.

Abstract: Disclosed are Methods and apparatuses for estimating one or more characteristics of the communications channel. The method comprises receiving a first wireless signal transmitted by a transmitter at a first set of frequencies in a first time slot; and receiving a second wireless signal transmitted by the transmitter at a second set of frequencies in a second time slot. The second set of frequencies partially overlaps with the first set of frequencies and the second time slot is different from the first time slot. The method further comprises jointly processing the first wireless signal and the second wireless signal to estimate the one or more characteristics of the communications channel. Corresponding apparatuses are configured to implement the methods.

Abstract: The present invention provides mutant RSV F molecules, such as those that can be, or are stabilized, in a pre-fusion conformation by the introduction of one or more DT cross-links. The present invention also provides methods of making such mutant RSV F molecules, compositions comprising such mutant RSV F molecules, and methods of use of such mutant RSV F molecules, for example in vaccination methods, therapeutic methods, and antibody production methods.

Abstract: Methods and apparatus are disclosed for sharing assistance information relating to an uplink signal transmitted by a first User Equipment. The assistance information may be used to assist a wireless communication device to intercept the uplink signal and measure its time of arrival. The assistance information may be used to assist in the calculation of a position or time, based on the measured time of arrival.

Abstract: A system and method in accordance with example embodiments may include systems and methods for generating and transforming data presentation. The method may include receiving, using a processor, a request for a web page, and submitting, by the processor, the request to a computer server system. The request can include a user identification and a user password. The method may further include receiving, from the computer server system, data corresponding to the requested web page. Further, the method includes storing, in a memory, the received data, and causing the received data to be shown on a display associated with the user device.

Abstract: A system and method in accordance with example embodiments may include systems and methods for generating and transforming data presentation. The method may include receiving, using a processor, a request for a web page, and submitting, by the processor, the request to a computer server system. The request can include a user identification and a user password. The method may further include receiving, from the computer server system, data corresponding to the requested web page. Further, the method includes storing, in a memory, the received data, and causing the received data to be shown on a display associated with the user device.

Abstract: A method and apparatus are provided for estimating characteristic differences between wireless signals transmitted from the same location in spaced apart frequency ranges. Also provided are a method and apparatus for estimating a combined time of arrival of the wireless signals, using the characteristic differences. A further method is provided, for identifying that two signals have been transmitted from the same location. Also disclosed is a method of maintaining a database of characteristic difference information.

Abstract: Disclosed are Methods and apparatuses for estimating one or more characteristics of the communications channel. The method comprises receiving a first wireless signal transmitted by a transmitter at a first set of frequencies in a first time slot; and receiving a second wireless signal transmitted by the transmitter at a second set of frequencies in a second time slot. The second set of frequencies partially overlaps with the first set of frequencies and the second time slot is different from the first time slot. The method further comprises jointly processing the first wireless signal and the second wireless signal to estimate the one or more characteristics of the communications channel. Corresponding apparatuses are configured to implement the methods.

Abstract: The present invention provides mutant RSV F molecules, such as those that can be, or are stabilized, in a pre-fusion conformation by the introduction of one or more DT cross-links. The present invention also provides methods of making such mutant RSV F molecules, compositions comprising such mutant RSV F molecules, and methods of use of such mutant RSV F molecules, for example in vaccination methods, therapeutic methods, and antibody production methods.

Abstract: Methods and apparatus for assisting positioning or timing calculations. In one aspect the invention provides a method for assisting a determination of a position or a time, the method comprising: obtaining first phase information, the first phase information characterizing a first phase of a first wireless signal transmitted by a transmitter at a first frequency and received by a first receiver at a first location; and obtaining second phase information, the second phase information characterizing a second phase of a second wireless signal transmitted by the transmitter at a second, different frequency and received by a second receiver at a second, different location. The method further comprises comparing the first phase information with the second phase information to produce phase comparison information; and using the phase comparison information to assist in the determination of a position or a time.

Abstract: Two wireless signals are received from transmitters in different locations transmitting at different frequencies. Phase information from the two signals is gathered for use in positioning and/or timing calculations. Calibration information is preferably also gathered to support the calculations. Information about the rate of change of phase may be gathered for use in velocity and timing drift calculations. The transmitters may be stations in a wireless infrastructure network. Assistance information may be gathered and shared to support the interception of uplink/downlink signals from the stations. Also disclosed are User Equipment, Base Stations, remote supporting services, elliptic hyperbolic relationships for interpreting and using the spatial variation of the phase difference, and positioning engines for use in the system.

Abstract: Methods and apparatus are disclosed for sharing, by a first User Equipment, interception-assistance information relating to an uplink signal transmitted by the first User Equipment. The interception-assistance information may be used to assist a second User Equipment to intercept the uplink signal and measure at least one characteristic of it. Calculation-assistance information may be used to assist in the calculation of a position or time, based on the measured characteristic.

Abstract: Disclosed herein are compositions for vaccination against respiratory syncytial virus (RSV) comprising a RSV F polypeptide stabilized in a prefusion conformation and an inulin adjuvant. Also disclosed herein are methods of vaccinating a subject against a respiratory syncytial virus (RSV) infection comprising administering to the subject an RSV F polypeptide stabilized in a prefusion conformation and an inulin adjuvant. In some embodiments, the subject is a female, and the method can reduce RSV infection in the subject and/or in the offspring of the subject. In some embodiments, the method decreases vaccine-enhanced respiratory disease (VERD) and/or eosinophilia in the subject or offspring of the subject.

Abstract: The present invention provides mutant RSV F molecules, such as those that can be, or are stabilized, in a pre-fusion conformation by the introduction of one or more DT cross-links. The present invention also provides methods of making such mutant RSV F molecules, compositions comprising such mutant RSV F molecules, and methods of use of such mutant RSV F molecules, for example in vaccination methods, therapeutic methods, and antibody production methods.

Abstract: Two wireless signals are received from transmitters in different locations transmitting at different frequencies. Phase information from the two signals is gathered for use in positioning and/or timing calculations. Calibration information is preferably also gathered to support the calculations. Information about the rate of change of phase may be gathered for use in velocity and timing drift calculations. The transmitters may be stations in a wireless infrastructure network. Assistance information may be gathered and shared to support the interception of uplink/downlink signals from the stations. Also disclosed are User Equipment, Base Stations, remote supporting services, elliptic hyperbolic relationships for interpreting and using the spatial variation of the phase difference, and positioning engines for use in the system.

Abstract: Methods and apparatus for assisting positioning or timing calculations. In one aspect the invention provides a method for assisting a determination of a position or a time, the method comprising: obtaining first phase information, the first phase information characterizing a first phase of a first wireless signal transmitted by a transmitter at a first frequency and received by a first receiver at a first location; and obtaining second phase information, the second phase information characterizing a second phase of a second wireless signal transmitted by the transmitter at a second, different frequency and received by a second receiver at a second, different location. The method further comprises comparing the first phase information with the second phase information to produce phase comparison information; and using the phase comparison information to assist in the determination of a position and/or a time.