Abstract: A lifting device having two frame assemblies which lie vertically over each other, the lower frame assembly being suspended on the upper frame assembly via lifting pulling means that can be wound by means of a lifting/lowering device. To stabilize the lower frame assembly in a first lateral direction, each of the lifting pulling means is diverted at least once over the extension thereof such that a diagonal section, running in an inclined manner relative to vertical, of each lifting pulling means crosses a directly adjacent diagonal section of another lifting pulling means, the other diagonal section running in an oppositely inclined manner. Diagonal pulling means, which can be wound by a tensioning device, extend between the two frame assemblies, two directly adjacent diagonal pulling means crossing each other such that the second frame assembly is also stabilized in a second lateral direction with respect to the upper frame assembly.

Abstract: The present invention relates to neutralizing antibodies of the human pituitary adenylate cyclase activating polypeptide type I receptor (PAC1) and pharmaceutical compositions comprising such antibodies. Methods of treating or preventing headache conditions, such as migraine and cluster headache, using the neutralizing antibodies are also described.

Abstract: The present invention relates to neutralizing antibodies of the human pituitary adenylate cyclase activating polypeptide type I receptor (PAC1) and pharmaceutical compositions comprising such antibodies. Methods of treating or preventing headache conditions, such as migraine and cluster headache, using the neutralizing antibodies are also described.

Abstract: The present invention relates to antagonist antibodies of the human calcitonin gene-related peptide (CGRP) receptor as well as bispecific antigen binding proteins derived from the anti-CGRP antibodies that bind to and inhibit both the human CGRP receptor and another target, such as the human pituitary adenylate cyclase activating polypeptide type I receptor (PAC1) receptor. Pharmaceutical compositions comprising the anti-CGRP receptor antibodies and bispecific antigen binding proteins as well as methods for producing them are also disclosed. Methods of using the anti-CGRP receptor antibodies and bispecific antigen binding proteins to ameliorate, treat, or prevent conditions associated with the CGRP and PAC1 receptors, such as chronic pain, migraine, and cluster headache, are also described.

Abstract: The present invention relates to neutralizing antibodies of the human pituitary adenylate cyclase activating polypeptide type I receptor (PAC1) and pharmaceutical compositions comprising such antibodies. Methods of treating or preventing headache conditions, such as migraine and cluster headache, using the neutralizing antibodies are also described.

Abstract: The present invention is directed to a CH3-containing molecule comprising (a) a first polypeptide comprising a CH3 domain and a negatively charged domain comprising consecutive negatively charged amino acid residues; and (b) a second polypeptide comprising a CH3 domain and a positively charged domain comprising consecutive positively charged amino acid residues. Also provided are methods for conjugating synthetic molecules to a multi-specific antigen binding molecule.

Abstract: The present invention relates to neutralizing antibodies of the human pituitary adenylate cyclase activating polypeptide type I receptor (PAC1) and pharmaceutical compositions comprising such antibodies. Methods of treating or preventing headache conditions, such as migraine and cluster headache, using the neutralizing antibodies are also described.

Abstract: The present invention relates to neutralizing antibodies of the human pituitary adenylate cyclase activating polypeptide type I receptor (PAC1) and pharmaceutical compositions comprising such antibodies. Methods of treating or preventing headache conditions, such as migraine and cluster headache, using the neutralizing antibodies are also described.

Abstract: A lifting apparatus has two frame assemblies positioned one above the other, so as to be mutually parallel, with respect to a vertical direction, the lower frame assembly suspended on the upper frame assembly using lifting traction means, such that the lower frame assembly can be drawn up towards the upper frame assembly by winding the lifting traction means, and the lower frame assembly can be lowered relative to the upper frame assembly by unwinding the lifting traction means. Oblique traction means extend between the frame assemblies that can be wound and unwound using a tensioning device, two of which mutually intersect such that the lower frame assembly is stabilized, relative to the upper frame assembly, in at least one deflection direction transverse to the vertical direction. The tensioning device may comprise four tensioning drives. According to an alternative exemplary embodiment, the tensioning device may comprise only two tensioning drives.

Abstract: The present invention relates to neutralizing antibodies of the human pituitary adenylate cyclase activating polypeptide type I receptor (PAC1) and pharmaceutical compositions comprising such antibodies. Methods of treating or preventing headache conditions, such as migraine and cluster headache, using the neutralizing antibodies are also described.

Abstract: A lifting apparatus for raising and lowering objects has two frame assemblies positioned one above the other, so as to be mutually parallel, with respect to a vertical direction, the lower frame assembly suspended on the upper frame assembly using lifting traction means, such that the lower frame assembly can be drawn up towards the upper frame assembly by winding the lifting traction means, and the lower frame assembly can be lowered relative to the upper frame assembly by unwinding the lifting traction means. The lifting apparatus has oblique traction means extending between the frame assemblies that can be wound and unwound using a tensioning device, two of which mutually intersect such that the lower frame assembly is stabilized, relative to the upper frame assembly, in at least one deflection direction transverse to the vertical direction.

Abstract: The present invention relates to neutralizing antibodies of the human pituitary adenylate cyclase activating polypeptide type I receptor (PAC1) and pharmaceutical compositions comprising such antibodies. Methods of treating or preventing headache conditions, such as migraine and cluster headache, using the neutralizing antibodies are also described.

Abstract: A lifting apparatus for raising and lowering objects has two frame assemblies positioned one above the other, so as to be mutually parallel, with respect to a vertical direction, the lower frame assembly suspended on the upper frame assembly using lifting traction means, such that the lower frame assembly can be drawn up towards the upper frame assembly by winding the lifting traction means, and the lower frame assembly can be lowered relative to the upper frame assembly by unwinding the lifting traction means. The lifting apparatus has oblique traction means extending between the frame assemblies that can be wound and unwound using a tensioning device, two of which mutually intersect such that the lower frame assembly is stabilized, relative to the upper frame assembly, in at least one deflection direction transverse to the vertical direction.

Abstract: A scissor-lift platform comprises a scissor mechanism (1) and scissor elements (3) that are connected to form scissor element pairs by central bearings (2). At least one scissor element (3) of a scissor element pair has a bearing receiving element (4) that is removably connected to the scissor element (3) in order to receive the central bearing (2).

Abstract: A scissor lift table (1) has a first base element (2) and a second base element (3) and a scissor (4). The scissor (4) has a first scissor part (6) and a second scissor part (7), wherein the first scissor part (6) and the second scissor part (7) are pivotable relative to one another about a scissor axis (5). The first base element (2) and the second base element (3) are connected by the scissor (4) such that a pivoting of the scissor parts (6, 7) relative to one another about the scissor axis (5) causes a change in the distance between the first base element (2) and the second base element (3), wherein the first scissor part (6) is pivotably borne on the first base element (2) using a fixed bearing (10) and the second scissor part (7) is displaceably and pivotably borne on the first base element (2) using a floating bearing (11).

Abstract: A conveyor frame for a conveyor system, having a lifting table, particularly a scissor-lift table, and a storage device for electrical energy for supplying an electrical lifting table drive for raising and/or lowering the lifting table, in which the maximum electrical power consumption of the lifting table is greater than the maximum electrical power consumption of all other electrical devices of the conveyor frame supplied by the storage device.

Abstract: A conveyor frame for a conveyor system, having a lifting table, particularly a scissor-lift table, and a storage device for electrical energy for supplying an electrical lifting table drive for raising and/or lowering the lifting table, in which the maximum electrical power consumption of the lifting table is greater than the maximum electrical power consumption of all other electrical devices of the conveyor frame supplied by the storage device.

Abstract: A scissor lift table (1) has a first base element (2) and a second base element (3) and a scissor (4). The scissor (4) has a first scissor part (6) and a second scissor part (7), wherein the first scissor part (6) and the second scissor part (7) are pivotable relative to one another about a scissor axis (5). The first base element (2) and the second base element (3) are connected by the scissor (4) such that a pivoting of the scissor parts (6, 7) relative to one another about the scissor axis (5) causes a change in the distance between the first base element (2) and the second base element (3), wherein the first scissor part (6) is pivotably borne on the first base element (2) using a fixed bearing (10) and the second scissor part (7) is displaceably and pivotably borne on the first base element (2) using a floating bearing (11).

Abstract: A scissors lift comprises an upper frame module (1) and a lower frame module (2), a scissor mechanism (3) and a drive unit (4). The upper frame module (1) and the lower frame module (2) are connected by the scissor mechanism (3) in such a way that a lifting movement, by which the spacing between the upper frame module (1) and lower frame module (2) changes, is rendered possible. The scissors lift, particularly the upper frame module (1) and/or the lower frame module (2), have a central portion (5) to which extension 6 and/or 7 that are pre-produced in fixed sizes and are fitted together in the manner of a modular construction system to make a scissors lifting lift of desired size.

Abstract: A scissor-lift platform comprises a scissor mechanism (1) and scissor elements (3) that are connected to form scissor element pairs by central bearings (2). At least one scissor element (3) of a scissor element pair has a bearing receiving element (4) that is removably connected to the scissor element (3) in order to receive the central bearing (2).