Patents by Inventor Christopher Moyes

Christopher Moyes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12281114
    Abstract: The present disclosure relates to compounds useful as modulators of neurokinin receptor 3 (NK3) for the treatment of conditions or disorders.
    Type: Grant
    Filed: August 12, 2024
    Date of Patent: April 22, 2025
    Assignee: KALLYOPE, INC.
    Inventors: Shuwen He, Scott B. Joseph, Christopher Moyes, Tesfaye Biftu, Santhosh F. Neelamkavil
  • Patent number: 11512065
    Abstract: This disclosure is directed, at least in part, to GPR119 agonists useful for the treatment of conditions or disorders involving the gut-brain axis. In some embodiments, the GPR119 agonists are gut-restricted compounds. In some embodiments, the condition or disorder is a metabolic disorder, such as diabetes, obesity, nonalcoholic steatohepatitis (NASH), or a nutritional disorder such as short bowel syndrome.
    Type: Grant
    Filed: February 3, 2022
    Date of Patent: November 29, 2022
    Assignee: KALLYOPE, INC.
    Inventors: Iyassu Sebhat, Shuwen He, Christopher Moyes
  • Patent number: 9006228
    Abstract: Substituted cyclopropyl compounds of the formula I: and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. The compounds are useful as agonists of the G-protein coupled receptor GPR-119. Pharmaceutical compositions and methods of treatment are also included.
    Type: Grant
    Filed: June 11, 2012
    Date of Patent: April 14, 2015
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Michael Miller, Andrew Stamford, Kallol Basu, Harold B. Wood, Duane DeMong, Wanying Sun, Joie Garfunkle, Christopher Moyes, Zhiyong Hu, Ping Liu, Scott D. Edmondson, Xing Dai, Byron Gabriel DuBois
  • Publication number: 20140128368
    Abstract: Substituted cyclopropyl compounds of the formula I: and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. The compounds are useful as agonists of the G-protein coupled receptor GPR-119. Pharmaceutical compositions and methods of treatment are also included.
    Type: Application
    Filed: June 11, 2012
    Publication date: May 8, 2014
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Michael Miller, Andrew Stamford, Kallol Basu, Harold B. Wood, Duane DeMong, Wanying Sun, Joie Garfunkle, Christopher Moyes, Zhiyong Hu, Ping Liu, Scott D. Edmondson, Xing Dai, Byron Gabriel DuBois
  • Patent number: 8465382
    Abstract: An Electronic Basketball Shooting Coach device is used to recondition the mind helping people maintain the proper elbow angle range when shooting a basketball. The self-contained device is worn on either arm below the elbow of a user. The ergonomically designed device is contained in the specially designed pocket of the sleeve before it can be attached below the elbow. The sleeve wraps around the upper-arm below the elbow and is held in place by hook-and-loop materials. The device has no internal movable parts. The device will articulate a phrase when the programmed non-adjustable trip point range. The device has a sleep mode to save on the common single cell's power and is reactivated by movement. The non-adjustable knob must be positioned up towards the fingers and aligned with the thumb or little finger. Two single cell sources must be added to energize the invention.
    Type: Grant
    Filed: October 23, 2010
    Date of Patent: June 18, 2013
    Inventor: Rashan Christopher Moye
  • Publication number: 20110045925
    Abstract: An Electronic Basketball Shooting Coach device is used to recondition the mind helping people maintain the proper elbow angle range when shooting a basketball. The invention is a self-contained device worn on either arm below the elbow. The ergonomically designed device must be contained in the specially designed pocket of the sleeve before it can be attached below the elbow. The sleeve wraps around the upper-arm below the elbow and is held in place by hook and loop materials. The device has no internal movable parts. The device will articulate a phrase when you past the programmed non-adjustable trip point range. The device has a sleep mode to save on the common single cell's power and is reactivated by movement. The non-adjustable knob must be positioned up towards the fingers and aligned with the thumb or little finger. Two single cell sources must be added to energize the invention.
    Type: Application
    Filed: October 23, 2010
    Publication date: February 24, 2011
    Inventor: Rashan Christopher Moye
  • Patent number: 7786305
    Abstract: The present invention is directed to compounds of the formula I: (wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2. The present invention is also directed to intermediates useful in the preparation of formula I compounds.
    Type: Grant
    Filed: May 28, 2004
    Date of Patent: August 31, 2010
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Richard Jiao, Gregori Morriello, Lihu Yang, Changyou Zhou, Shankaran Kothandaraman, Christopher Moyes
  • Publication number: 20090298621
    Abstract: A basketball shooting coach aid device used to help individuals learn how to keep their elbow tucked to the side of their body while keeping the forearm and elbow at a 90 degree angle while shooting a basketball. The basketball shooting coach is a self contained square in shape device that is worn or either the right or left arm depending on the individual wearing the unit. The device consists of a speaker, IC voice chip, batteries, arm straps, and an adjustable sensitivity switch all enclosed in a light weight plastic cover. The basketball shooting aid casing will have a speaker grille to help increase the volume, a sensitivity control cavity to control how sensitive the device is, a Velcro straps that allow the device to fit over an individual's forearm, and an on and off switch. If the alarm sounds when the individual uses the device then the individual is using bad form.
    Type: Application
    Filed: July 14, 2008
    Publication date: December 3, 2009
    Inventor: Rashan Christopher Moye
  • Patent number: 7230008
    Abstract: The present invention is directed to methods for treating, preventing, ameliorating, controlling or reducing the risk of an inflammatory or immunoregulatory disorder or disease, which method comprises the administration to a patient of an effective amount of the compound of formula I: (wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.
    Type: Grant
    Filed: August 20, 2004
    Date of Patent: June 12, 2007
    Assignee: Merck & Co, Inc.
    Inventors: Richard Jiao, Gabor Butora, Stephen D. Goble, Deodialsingh Guiadeen, Sander G. Mills, Gregori Morriello, Alexander Pasternak, Cheng Tang, Lihu Yang, Changyou Zhou, Shankaran Kothandaraman, Christopher Moyes
  • Publication number: 20070063789
    Abstract: A compact multilayer signal processing system. In the illustrative embodiment, the system is adapted for use with microwave signals. The system includes a first mechanism for receiving an input signal and selectively routing the input signal onto a first signal path. A second mechanism routes the input signal along the first signal path vertically through one or more layers to a first circuit component. The first circuit component outputs an adjusted signal in response to receipt of the input signal. A third mechanism directs the adjusted signal to the output of the system. In a specific embodiment, the one or more layers include one or more groundplane layers. In this embodiment, the first mechanism includes an input switching network in communication with a controller. The switching network is positioned on a switching layer and communicates with one or more controllers to facilitate selectively switching the input signal onto one of plural input signal paths.
    Type: Application
    Filed: September 20, 2005
    Publication date: March 22, 2007
    Inventors: Lawrence Dalconzo, Christopher Moye, Eduardo Barrientos, David Drapeau, Michael Crnkovich, Tamrat Akale
  • Patent number: 7166614
    Abstract: The present invention is directed to compounds of the formula I: I(wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity.
    Type: Grant
    Filed: April 25, 2003
    Date of Patent: January 23, 2007
    Assignees: Merck & Co., Inc., Merck Sharp & Dohme Limited
    Inventors: Richard Jiao, Stephen D. Goble, Sander G. Mills, Gregori Morriello, Alexander Pasternak, Lihu Yang, Changyou Zhou, Gabor Butora, Shankaran Kothandaraman, Deodialsingh Guiadeen, Christopher Moyes
  • Publication number: 20060089379
    Abstract: The present invention is directed to compounds of the formula I: I(wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.
    Type: Application
    Filed: April 25, 2003
    Publication date: April 27, 2006
    Inventors: Richard Jiao, Stephen Goble, Sander Mills, Gregori Morriello, Alexander Pasternak, Lihu Yang, Changyou Zhou, Gabor Butora, Shankaran Kothandaraman, Deodialsingh Guiadeen, Christopher Moyes
  • Publication number: 20060040947
    Abstract: the present invention provides a compound of formula (I): wherein V represents NR5, O, S, SO or S(O)2; W and X each independently represent CH or N; Y represents N, CH or C—Ar2, with the proviso that at least one, but no more than two, of W, X and Y are N; Z represents CH or C—Ar2, with the proviso that when Y is N or CH then Z is C—Ar2, and with the further proviso that when Y is C—Ar2 then Z is CH; Ar1 represents a fused 9 or 10 membered heterobicyclic ring system containing one, two, three or four heteroatoms selected from nitrogen, oxygen and sulfur, wherein at least one of the rings in said ring system is aromatic; Ar2 represents an aromatic ring selected from phenyl, pyridyl, pyrimidinyl and pyridazinyl which is optionally fused and substituted; R1 represents halogen, hydroxy, oxo, C1-6alkyl, C2-6alkenyl, C2-6alkynyl, haloC1-6alkyl, hydroxyC1-6alkyl, C1-6alkoxy, haloC1-6alkoxy, hydroxyC1-6alkoxy, C3-7cycloalkyl, C3-7cycloalkoxy, C3-5cycloalkylC1-4alkyl, cyano, nitro, SR6, SOR6, SO2R6, COR6, NR3COR6, CON
    Type: Application
    Filed: November 14, 2003
    Publication date: February 23, 2006
    Inventors: Peter Blurton, Frank Burkamp, Sttephen Fletcher, Gregory Hollingworth, A. Brian Jones, edward McIver, Christopher Moyes, Lauren Rogers
  • Publication number: 20060030582
    Abstract: The present invention is directed to methods for treating, preventing, ameliorating, controlling or reducing the risk of a disorder or disease, which method comprises the administration to a patient of an effective amount of the compound of formula I: I (wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.
    Type: Application
    Filed: April 8, 2005
    Publication date: February 9, 2006
    Inventors: Julie DeMartino, Taro Akiyama, Mary Struthers, Lihu Yang, Joel Berger, Gregori Morriello, Alexander Pastemak, Changyou Zhou, Sander Mills, Gabor Butora, Shankaran Kothandaraman, Deodialsingh Guiadeen, Cheng Tang, Richard Jiao, Stephen Goble, Christopher Moyes
  • Publication number: 20050197342
    Abstract: The present invention provides a compound of formula I: Y-J-NH-Z??(I) wherein: Y is a quinoline or isoquinoline optionally substituted with one or two substituents independently chosen from hydroxy, halogen, haloC1-4alkyl, C1-4alkyl, C1-4alkoxy, haloC1-4alkoxy, nitro and amino; J is pyridine, pyridazine, pyrazine, pyrimidine or triazine optionally substituted with one or two substituents independently chosen from hydroxy, halogen, haloC1-4alkyl, C1-4alkyl, C3-5cycloalkyl, C1-4alkoxy, hydroxyC1-4alkyl, cyano, hydroxy, C1-4cycloalkoxy, C1-4alkylthio, haloC1-4alkoxy, nitro, Q, (CH2)pQ, —NR2R3, —(CH2)pNR2R3 and —O(CH2)pNR2R3; wherein J is substituted at positions meta to each other by NH and Y; and Z is phenyl or pyridyl optionally substituted with one or two substituents independently selected from halogen, haloC1-4alkyl, C1-4alkyl, C1-4alkoxy, haloC1-4alkoxy, nitro and amino; Q is phenyl, a five-membered heterocyclic ring containing one, two, three or four heteroatoms chosen from O, N and S, at most one
    Type: Application
    Filed: November 9, 2004
    Publication date: September 8, 2005
    Inventors: Gregory Hollingworth, A. Jones, Edward McIver, Christopher Moyes, Lauren Rogers
  • Publication number: 20050107422
    Abstract: The present invention is directed to methods for treating, preventing, ameliorating, controlling or reducing the risk of an inflammatory or immunoregulatory disorder or disease, which method comprises the administration to a patient of an effective amount of the compound of formula I: (wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.
    Type: Application
    Filed: August 20, 2004
    Publication date: May 19, 2005
    Inventors: Richard Jiao, Gabor Butora, Stephen Goble, Deodialsingh Guiadeen, Sander Mills, Gregori Morriello, Alexander Pasternak, Cheng Tang, Lihu Yang, Changyou Zhou, Shankaran Kothandaraman, Christopher Moyes
  • Publication number: 20050107388
    Abstract: The present invention provides compounds of formula (I); pharmaceutically acceptable salts and N-oxides thereof in which A, B, D and E are C or N with the proviso that one or more are N, R1, R2, R3, R4, R5 and R6 are simple substituents, n is 0-3 and y is an aryl, heteroaryl, carbocyclyl or fused-carbocyclyl group; as VR-1 antagonists for treating conditions or diseases in which pain and/or inflammation predominates; the use of the same for manufacturing medicaments, pharmaceutical compositions comprising them and methods of treatment utilising them.
    Type: Application
    Filed: March 21, 2003
    Publication date: May 19, 2005
    Inventors: Rebecca Brown, Victoria Doughty, Gregory Hollingworth, A. Jones, Matthew Lindon, Christopher Moyes, Lauren Rogers
  • Publication number: 20050101628
    Abstract: The present invention is directed to compounds of the formula I: (wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2. The present invention is also directed to intermediates useful in the preparation of formula I compounds.
    Type: Application
    Filed: May 28, 2004
    Publication date: May 12, 2005
    Inventors: Richard Jiao, Gregori Morriello, Lihu Yang, Christopher Moyes, Changyou Zhou, Shankaran Kothandaraman
  • Patent number: 6812234
    Abstract: The present invention is directed to compounds of the formula I: (wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.
    Type: Grant
    Filed: April 29, 2003
    Date of Patent: November 2, 2004
    Assignees: Merck & Co., Inc., Merck Sharp & Dohme Ltd.
    Inventors: Richard Jiao, Gregori Morriello, Lihu Yang, Stephen D. Goble, Sander G. Mills, Alexander Pasternak, Changyou Zhou, Gabor Butora, Shankaran Kothandaraman, Deodialsingh Guiadeen, Christopher Moyes, Cheng Tang
  • Publication number: 20040167156
    Abstract: The present invention is directed to compounds of the formula I: 1
    Type: Application
    Filed: April 29, 2003
    Publication date: August 26, 2004
    Inventors: Richard Jiao, Gregori Morriello, Lihu Yang, Stephen D. Goble, Sander G. Mills, Alexander Pasternak, Changyou Zhou, Gabor Butora, Shankaran Kothandaraman, Deodialsingh Guiadeen, Christopher Moyes, Cheng Tang