Patents by Inventor Christopher N. Johnson

Christopher N. Johnson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-phenylpyrrole derivatives as dopamine D.sub.3 receptor antagonists
    Patent number: 5637609
    Abstract: A compound of formula (I): ##STR1## which have high affinity for dopamine D.sub.3 receptors and thus have potential as antipsychotic agents.
    Type: Grant
    Filed: January 29, 1996
    Date of Patent: June 10, 1997
    Assignee: SmithKline Beecham plc
    Inventors: Geoffrey Stemp, Christopher N. Johnson
  • Phenylpyrrole derivatives and their use as dopamine D.sub.3 antagonists
    Patent number: 5637600
    Abstract: The present invention relates to pyrrole compounds, processes for their preparation, pharmaceutical compositions containing them and their use in therapy, in particular as anti-psychotic agents.
    Type: Grant
    Filed: August 13, 1996
    Date of Patent: June 10, 1997
    Assignee: SmithKline Beecham p.l.c.
    Inventor: Christopher N. Johnson
  • 5-(2-oxyphenyl)-pyrrole derivatives as dopamine D.sub.3 receptor antagonists
    Patent number: 5523299
    Abstract: Compounds of formula (I), ##STR1## wherein R.sup.1 represents C.sub.1-4 alkyl; and R.sup.2, R.sup.3, R.sup.4 and R.sup.5 each independently represent hydrogen, halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, C.sub.1-4 alkoxyC.sub.1-4 alkyl, C.sub.1-4 alkylsulphonyl, trifluoromethylsulphonyl; optionally substituted arylsulphonyl, optionally substituted heteroarylsulphonyl, optionally substituted aralkylsulphonyl, optionally substituted heteroaralkylsulphonyl, nitro, cyano, amino, mono- or di-alkylamino, trifluoromethyl, trifluoromethoxy, hydroxyl, hydroxyalkyl, C.sub.1-4 alkylthio, C.sub.1-4 alkanoyl, C.sub.1-4 alkoxycarbonyl, aminosulphonyl, alkylaminosulphonyl or dialkylaminosulphonyl; or R.sup.1 and R.sup.2 together form a linking chain-(CH.sub.2).sub.m Op (wherein m is 2 to 4 and p is zero or 1) which chain may be optionally substituted by one or two C.sub.1-4 alkyl groups; and Y represents a group selected from (a) or (b) wherein R.sup.6 and R.sup.7 independently represent hydrogen, C.sub.
    Type: Grant
    Filed: February 3, 1995
    Date of Patent: June 4, 1996
    Assignee: SmithKline Beecham PLC
    Inventors: Geoffrey Stemp, Michael S. Hadley, David J. Nash, Christopher N. Johnson
  • 4-amino-benzo[b]thieno[2,3-b]pyridines useful in the treatment of CNS disorders
    Patent number: 5093493
    Abstract: Compounds of formula (I) or pharmaceutically acceptable salts thereof: ##STR1## wherein: R.sub.1 is hydrogen, C.sub.1-6 alkyl, phenyl or phenyl C.sub.1-4 alkyl wherein the phenyl moiety is optionally substituted by one or more C.sub.1-6 alkyl, C.sub.1-6 alkoxy, C.sub.1-6 alkylthio, hydroxy, C.sub.2-7 alkanoyl, halo, trifluoromethyl, nitro, amino optionally substituted by one or two C.sub.1-6 alkyl groups or by C.sub.2-7 alkanoyl, cyano, carbamoyl or carboxy groups;R.sub.2, R.sub.3 and R.sub.4 are independently selected from hydrogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxycarbonyl, C.sub.1-6 alkylthio, C.sub.2-7 alkanoyl, trifluoromethyl, cyano, carbamoyl and carboxy, and phenyl or phenyl C.sub.1-4 alkyl in which any phenyl moiety is optionally substituted by C.sub.1-6 alkyl, C.sub.1-6 alkoxy, C.sub.1-6 alkoxy carbonyl, C.sub.1-6 alkylthio, hydroxy, C.sub.2-7 alkanoyl, chloro, fluoro, trifluoromethyl, nitro or amino optionally substituted by one or two C.sub.1-6 alkyl groups or by C.sub.
    Type: Grant
    Filed: March 12, 1990
    Date of Patent: March 3, 1992
    Assignee: Beecham Group p.l.c.
    Inventors: Mervyn Thompson, Ian T. Forbes, Christopher N. Johnson