Abstract: Concepts for creating a metatype tree for metatype introspection are presented. One example comprises decoding a parent metatype from a synthetic dataset by decoding one or more child metatypes of the parent metatype. The method then comprises creating a metatype tree comprising a parent node and one or more child nodes of the parent node. The parent node comprises the decoded parent metatype and the one or more child nodes of the parent node comprise the one or more decoded child metatypes.

Abstract: Provided herein are compounds of formula (II): or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein m, n, p, R1, R2, R3, L1, L2, L3, R4, X1, X2, X3, and X4 are as defined herein. Also provided are methods of preparing compounds of formula (II), or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing. Also provided are methods of inhibiting APOL1 and methods of treating an APOL1-mediated disease, disorder, or condition in an individual.

Abstract: A cooking system includes a housing defining a hollow chamber configured to receive food. The housing has an upper portion defining an opening to said hollow chamber. A lid is movable relative to the housing between an open position and a closed position. The lid seals the opening to the hollow chamber when in the closed position. A portion of the lid is selectively positionable to form a pressure-tight heating volume between the hollow chamber and the portion of said lid. At least one heating element is associated with at least one of the housing and the lid. The at least one heating element is arranged within the pressure-tight heating volume.

Abstract: A heat-assisted magnetic recording head includes a laser, a near-field transducer, a primary waveguide, a secondary waveguide, and a photodiode. The laser is configured to emit electromagnetic radiation. The near-field transducer is configured to focus and emit an optical near-field. The primary waveguide configured to receive the electromagnetic radiation and propagate the electromagnetic radiation toward and proximal to the near-field transducer. The secondary waveguide configured to receive a portion of the electromagnetic radiation from the primary waveguide. The photodiode configured to receive the portion of the electromagnetic radiation from the secondary waveguide and emit a signal that represents a magnitude of the electromagnetic radiation that the laser emits.

Abstract: A system for modeling risk of rail buckling in railroad infrastructure is presented. The system can receive a myriad of data related to railroad tracks and/or railroad operations, and weight the data using specially-designed weighting factors that can be unique to each data type. The weighted data can be transformed via specialized algorithms to generate location scores reflective of a risk isolated to a particular area. The system can further utilize additional specialized algorithms to elucidate how such isolated risk can be extrapolated from one location to another. The system can implement a multilayer approach, formulating one or more layers of risk models and aggregating such models into an overarching risk model that can more-accurately forecast risk of rail buckling in a railroad track.

Abstract: Some embodiments support embedding of a notebooks software component in a surrounding host application, thereby promoting consistency of notebook user interfaces and user experiences between different kinds of applications. For instance, the notebook access added to an integrated development environment (IDE) may be aesthetically consistent with the notebook access added to a business analytics tool from the same vendor as the IDE. Departures from the aesthetic are still supported, e.g., a notebook access provided in a video gaming environment to teach gamers programming skills may have the same aesthetic as the simulated world of the video game, rather than an IDE aesthetic or an enterprise software aesthetic. Direct integration or proxied integration architectures may be used. Efficiencies may be gained by distinguishing between notebook viewing, editing, and executing operations, and providing more computationally expensive resources only as needed for the notebook access being performed.

Abstract: A heat-assisted magnetic recording head includes a laser, a near-field transducer, a primary waveguide, a secondary waveguide, and a photodiode. The laser is configured to emit electromagnetic radiation. The near-field transducer is configured to focus and emit an optical near-field. The primary waveguide configured to receive the electromagnetic radiation and propagate the electromagnetic radiation toward and proximal to the near-field transducer. The secondary waveguide configured to receive a portion of the electromagnetic radiation from the primary waveguide. The photodiode configured to receive the portion of the electromagnetic radiation from the secondary waveguide and emit a signal that represents a magnitude of the electromagnetic radiation that the laser emits.

Abstract: In operation, packets traverse the packet processing data structure, and the network processing represented by each object in the data structure is applied to each packet. From time to time, the packet processing data structure may need to be updated. Embodiments of the present disclosure provide for lock-free updating of a packet processing data structure by means of epoch-based garbage collection. In embodiments, a particular past packet processing epoch is considered to be no longer referenced by any cores when the sequence numbers recorded in each said memory location are different to the sequence number of that particular past packet processing epoch. The deletion thread checks both whether a past epoch is being referenced by any packets and whether it is being reference by any cores. Thus memory is safely freed without having any impact on any packet processing which may be occurring in parallel to the deletion thread.

Abstract: A recording head includes a channel waveguide that delivers light to a media-facing surface. A near-field transducer (NFT) is at an end of the channel waveguide and proximate to the media-facing surface. A laser including an active region has a longitudinal axis corresponding to a propagation direction of the channel waveguide. The active region includes a back facet and a front facet proximate the NFT. The front facet has a surface shape configured to suppress back reflection of the light.

Abstract: The invention relates to compositions comprising therapeutic antibodies, and uses and methods for increasing the potency of therapeutic antibodies. In particular, the invention provides a composition comprising (i) an agent which reduces Fc receptor binding of endogenous serum antibodies, and (ii) a therapeutic antibody, preferably a therapeutic antibody which is resistant to the agent. The therapeutic antibody may be administered to the subject after a set time interval, or the blood of the subject may be treated with the agent prior to administration of the therapeutic antibody.

Abstract: Systems and methods for predicting drilling tool failure based on an analysis of at least one of a plot of jerk and inverse jerk for the drilling tool and a plot of drilling tool failure pattern trends data.

Abstract: Described are heat assisted magnetic read-write heads that include a coupler, a waveguide, a transducer, and appurtenant structures, as well as related methods.

Abstract: An implantable intravascular pressure sensor comprising a first transducer arranged to provide a pressure dependent signal in response to alternating electrical signals of a first frequency band, a second transducer arranged to provide a reference signal in response to alternating electrical signals of a second frequency band different from the first frequency band and an antenna coupling for sending and receiving said signals.

Abstract: A recording head includes a channel waveguide that delivers light to a media-facing surface. A near-field transducer (NFT) is at an end of the channel waveguide and proximate to the media-facing surface. A laser including an active region has a longitudinal axis corresponding to a propagation direction of the channel waveguide. The active region includes a back facet and a front facet proximate the NFT. The front facet has a surface shape configured to suppress back reflection of the light.

Abstract: A system for modeling risk of rail buckling in railroad infrastructure is presented. The system can receive a myriad of data related to railroad tracks and/or railroad operations, and weight the data using specially-designed weighting factors that can be unique to each data type. The weighted data can be transformed via specialized algorithms to generate location scores reflective of a risk isolated to a particular area. The system can further utilize additional specialized algorithms to elucidate how such isolated risk can be extrapolated from one location to another. The system can implement a multilayer approach, formulating one or more layers of risk models and aggregating such models into an overarching risk model that can more-accurately forecast risk of rail buckling in a railroad track.

Abstract: An implantable intravascular device for deployment inside a human or animal, the apparatus comprising a body of crystalline material and a membrane of crystalline material fixed to the body by a hermetic bond an assembly of components carried on said crystalline material and arranged for responding to electrical signals wherein the body and the membrane at least partially encapsulate the assembly.

Abstract: Embodiments of the present invention provide concepts for tracing a request in a distributed system architecture comprising one or more distributed services. A request is received at a network traffic component on one of a plurality of sockets, which are monitored by a span correlation component. Span data is obtained from the received request and a process identification component is adapted to identify a process associated with the request based on the span data. The span correlation component is adapted to identify a socket connection made by the identified process and correlate the socket connection with the span data, thereby generating span correlation data.

Abstract: An electromechanical system for generating a CPR-corrupted ECG signal is provided. The electromechanical system may include an ECG signal generator electrically coupled to a first contact of an AED. The electromechanical system may further include a potentiometer electrically coupled to the ECG signal generator and a second contact of the AED. The electromechanical system may further include a compression mechanism. The compression mechanism may be configured to receive a vertical force and adjust an impedance of the potentiometer according to the vertical force. The compression mechanism may include a rack having a plurality of teeth and an initial position. The rack may be configured to translate to a second position according to the vertical force. The compression mechanism may further include a gear with a plurality of teeth engaged with the teeth of the rack such that the gear rotates according to the translation of the rack.

Abstract: A method, system, and computer program product for predicting microservices required for incoming requests for reducing the start latency of serverless microservices. The method may include obtaining tracing data of microservices of an application for historical requests processed by the application. The method may also include grouping the tracing data based on common request attributes. The method may also include aggregating each group into rules relating the common request attributes to lists of microservices. The method may also include building a predictive model formed of the rules for processing incoming requests to obtain a list of predicted microservices required for the incoming request based on attributes of the incoming request.

Abstract: In operation, packets traverse the packet processing data structure, and the network processing represented by each object in the data structure is applied to each packet. From time to time, the packet processing data structure may need to be updated. Embodiments of the present disclosure provide for lock-free updating of a packet processing data structure by means of epoch-based garbage collection. In embodiments, a particular past packet processing epoch is considered to be no longer referenced by any cores when the sequence numbers recorded in each said memory location are different to the sequence number of that particular past packet processing epoch. The deletion thread checks both whether a past epoch is being referenced by any packets and whether it is being reference by any cores. Thus memory is safely freed without having any impact on any packet processing which may be occurring in parallel to the deletion thread.