Patents by Inventor Christopher P. Boucher

Christopher P. Boucher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High-purity large-scale preparation of stannsoporfin
    Patent number: 11078220
    Abstract: Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions.
    Type: Grant
    Filed: May 1, 2020
    Date of Patent: August 3, 2021
    Assignee: Mallinckrodt Hospital Products IP Limited
    Inventors: George S. Drummond, Robert Caroselli, Keith A. Cooke, Daniel Levin, David G. Roe, Christopher P. Boucher
  • HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN
    Publication number: 20200255458
    Abstract: Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions.
    Type: Application
    Filed: May 1, 2020
    Publication date: August 13, 2020
    Inventors: George S. Drummond, Robert Caroselli, Keith A. Cooke, Daniel Levin, David G. Roe, Christopher P. Boucher
  • High-purity large-scale preparation of stannsoporfin
    Patent number: 10662209
    Abstract: Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: May 26, 2020
    Assignee: Mallinckrodt Hospital Products IP Limited
    Inventors: George S. Drummond, Robert Caroselli, Keith A. Cooke, Daniel Levin, David G. Roe, Christopher P. Boucher
  • Methods for synthesizing metal mesoporphyrins
    Patent number: 10533024
    Abstract: Embodiments describe methods of synthesizing metal mesoporphyrin compounds. In embodiments, a metal mesoporphyrin compound may be formed by hemin transmetallation and subsequent hydrogenation of the tin protoporphyrin IX to form a metal mesoporphyrin. In other embodiments, a method of synthesizing a metal mesoporphyrin compound comprises forming a protoporphyrin methyl ester from hemin and converting the protoporphyrin methyl ester intermediate to a metal mesoporphyrin compound through metal insertion and hydrogenation. In other embodiments, a metal mesoporphyrin compound may be formed from hemin by a hydrogen-free hydrogenation method to form a mesoporphyrin IX intermediate followed by metal insertion and hydrogenation. In embodiments, a method of synthesizing a metal mesoporphyrin compound comprises forming a mesoporphyrin IX dihydrochloride intermediate compound and converting the mesoporphyrin IX intermediate to a metal mesoporphyrin compound through metal insertion.
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: January 14, 2020
    Assignee: MALLINCKRODT HOSPTIAL PRODUCTS IP LIMITED
    Inventors: Christopher P. Boucher, David Roe
  • HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN
    Publication number: 20190202846
    Abstract: Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions.
    Type: Application
    Filed: March 11, 2019
    Publication date: July 4, 2019
    Inventors: George S. Drummond, Robert Caroselli, Keith A. Cooke, Daniel Levin, David G. Roe, Christopher P. Boucher
  • High-purity large-scale preparation of stannsoporfin
    Patent number: 10273255
    Abstract: Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions.
    Type: Grant
    Filed: January 11, 2018
    Date of Patent: April 30, 2019
    Assignee: INFACARE PHARMACEUTICAL CORPORATION
    Inventors: George S. Drummond, Robert Caroselli, Keith A. Cooke, Daniel Levin, David G. Roe, Christopher P. Boucher
  • METHODS FOR SYNTHESIZING METAL MESOPORPHYRINS
    Publication number: 20190002481
    Abstract: Embodiments describe methods of synthesizing metal mesoporphyrin compounds. In embodiments, a metal mesoporphyrin compound may be formed by hemin transmetallation and subsequent hydrogenation of the tin protoporphyrin IX to form a metal mesoporphyrin. In other embodiments, a method of synthesizing a metal mesoporphyrin compound comprises forming a protoporphyrin methyl ester from hemin and converting the protoporphyrin methyl ester intermediate to a metal mesoporphyrin compound through metal insertion and hydrogenation. In other embodiments, a metal mesoporphyrin compound may be formed from hemin by a hydrogen-free hydrogenation method to form a mesoporphyrin IX intermediate followed by metal insertion and hydrogenation. In embodiments, a method of synthesizing a metal mesoporphyrin compound comprises forming a mesoporphyrin IX dihydrochloride intermediate compound and converting the mesoporphyrin IX intermediate to a metal mesoporphyrin compound through metal insertion.
    Type: Application
    Filed: September 7, 2018
    Publication date: January 3, 2019
    Inventors: Christopher P. Boucher, David Roe
  • HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN
    Publication number: 20180134735
    Abstract: Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions.
    Type: Application
    Filed: January 11, 2018
    Publication date: May 17, 2018
    Inventors: George S. DRUMMOND, Robert CAROSELLI, Keith A. COOKE, Daniel LEVIN, David G. ROE, Christopher P. BOUCHER
  • High-purity large-scale preparation of stannsoporfin
    Patent number: 9902745
    Abstract: Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: February 27, 2018
    Assignee: INFACARE PHARMACEUTICAL CORPORATION
    Inventors: George S. Drummond, Robert Caroselli, Keith A. Cooke, Daniel Levin, David G. Roe, Christopher P. Boucher
  • METHODS FOR SYNTHESIZING METAL MESOPORPHYRINS
    Publication number: 20170260217
    Abstract: Embodiments describe methods of synthesizing metal mesoporphyrin compounds. In embodiments, a metal mesoporphyrin compound may be formed by hemin transmetallation and subsequent hydrogenation of the tin protoporphyrin IX to form a metal mesoporphyrin. In other embodiments, a method of synthesizing a metal mesoporphyrin compound comprises forming a protoporphyrin methyl ester from hemin and converting the protoporphyrin methyl ester intermediate to a metal mesoporphyrin compound through metal insertion and hydrogenation. In other embodiments, a metal mesoporphyrin compound may be formed from hemin by a hydrogen-free hydrogenation method to form a mesoporphyrin IX intermediate followed by metal insertion and hydrogenation. In embodiments, a method of synthesizing a metal mesoporphyrin compound comprises forming a mesoporphyrin IX dihydrochloride intermediate compound and converting the mesoporphyrin IX intermediate to a metal mesoporphyrin compound through metal insertion.
    Type: Application
    Filed: May 24, 2017
    Publication date: September 14, 2017
    Inventors: Christopher P. BOUCHER, David ROE
  • Methods for synthesizing metal mesoporphyrins
    Patent number: 9688705
    Abstract: Embodiments describe methods of synthesizing metal mesoporphyrin compounds. In embodiments, a metal mesoporphyrin compound may be formed by hemin transmetallation and subsequent hydrogenation of the tin protoporphyrin IX to form a metal mesoporphyrin. In other embodiments, a method of synthesizing a metal mesoporphyrin compound comprises forming a protoporphyrin methyl ester from hemin and converting the protoporphyrin methyl ester intermediate to a metal mesoporphyrin compound through metal insertion and hydrogenation. In other embodiments, a metal mesoporphyrin compound may be formed from hemin by a hydrogen-free hydrogenation method to form a mesoporphyrin IX intermediate followed by metal insertion and hydrogenation. In embodiments, a method of synthesizing a metal mesoporphyrin compound comprises forming a mesoporphyrin IX dihydrochloride intermediate compound and converting the mesoporphyrin IX intermediate to a metal mesoporphyrin compound through metal insertion.
    Type: Grant
    Filed: October 5, 2015
    Date of Patent: June 27, 2017
    Assignee: INFACARE PHARMACEUTICAL CORPORATION
    Inventors: Christopher P. Boucher, David Roe
  • HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN
    Publication number: 20170073362
    Abstract: Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions.
    Type: Application
    Filed: November 4, 2016
    Publication date: March 16, 2017
    Inventors: George S. DRUMMOND, Robert CAROSELLI, Keith A. COOKE, Daniel LEVIN, David G. ROE, Christopher P. BOUCHER
  • High-purity large-scale preparation of stannsoporfin
    Patent number: 9517239
    Abstract: Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions.
    Type: Grant
    Filed: July 8, 2015
    Date of Patent: December 13, 2016
    Assignee: Infacare Pharmaceutical Corporation
    Inventors: George S. Drummond, Robert Caroselli, Keith A. Cooke, Daniel Levin, David G. Roe, Christopher P. Boucher
  • METHODS FOR SYNTHESIZING METAL MESOPORPHYRINS
    Publication number: 20160024124
    Abstract: Embodiments describe methods of synthesizing metal mesoporphyrin compounds. In embodiments, a metal mesoporphyrin compound may be formed by hemin transmetallation and subsequent hydrogenation of the tin protoporphyrin IX to form a metal mesoporphyrin. In other embodiments, a method of synthesizing a metal mesoporphyrin compound comprises forming a protoporphyrin methyl ester from hemin and converting the protoporphyrin methyl ester intermediate to a metal mesoporphyrin compound through metal insertion and hydrogenation. In other embodiments, a metal mesoporphyrin compound may be formed from hemin by a hydrogen-free hydrogenation method to form a mesoporphyrin IX intermediate followed by metal insertion and hydrogenation. In embodiments, a method of synthesizing a metal mesoporphyrin compound comprises forming a mesoporphyrin IX dihydrochloride intermediate compound and converting the mesoporphyrin IX intermediate to a metal mesoporphyrin compound through metal insertion.
    Type: Application
    Filed: October 5, 2015
    Publication date: January 28, 2016
    Inventors: Christopher P. BOUCHER, David ROE
  • HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN
    Publication number: 20160000802
    Abstract: Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions.
    Type: Application
    Filed: July 8, 2015
    Publication date: January 7, 2016
    Inventors: George S. DRUMMOND, Robert CAROSELLI, Keith A. COOKE, Daniel LEVIN, David G. ROE, Christopher P. BOUCHER
  • Methods for synthesizing metal mesoporphyrins
    Patent number: 9181285
    Abstract: Embodiments describe methods of synthesizing metal mesoporphyrin compounds. In embodiments, a metal mesoporphyrin compound may be formed by hemin transmetallation and subsequent hydrogenation of the tin protoporphyrin IX to form a metal mesoporphyrin. In other embodiments, a method of synthesizing a metal mesoporphyrin compound comprises forming a protoporphyrin methyl ester from hemin and converting the protoporphyrin methyl ester intermediate to a metal mesoporphyrin compound through metal insertion and hydrogenation. In other embodiments, a metal mesoporphyrin compound may be formed from hemin by a hydrogen-free hydrogenation method to form a mesoporphyrin IX intermediate followed by metal insertion and hydrogenation. In embodiments, a method of synthesizing a metal mesoporphyrin compound comprises forming a mesoporphyrin IX dihydrochloride intermediate compound and converting the mesoporphyrin IX intermediate to a metal mesoporphyrin compound through metal insertion.
    Type: Grant
    Filed: April 15, 2014
    Date of Patent: November 10, 2015
    Assignee: INFACARE PHARMACEUTICAL CORPORATION
    Inventors: Christopher P. Boucher, David Roe
  • High-purity large-scale preparation of stannsoporfin
    Patent number: 9107927
    Abstract: Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions.
    Type: Grant
    Filed: August 14, 2014
    Date of Patent: August 18, 2015
    Assignee: Infacare Pharmaceutical Corporation
    Inventors: George S. Drummond, Robert Caroselli, Keith A. Cooke, Daniel Levin, David G. Roe, Christopher P. Boucher
  • HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN
    Publication number: 20150051184
    Abstract: Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions.
    Type: Application
    Filed: August 14, 2014
    Publication date: February 19, 2015
    Inventors: George S. DRUMMOND, Robert CAROSELLI, Keith A. COOKE, Daniel LEVIN, David G. ROE, Christopher P. BOUCHER
  • High-purity large-scale preparation of stannsoporfin
    Patent number: 8835416
    Abstract: Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions.
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: September 16, 2014
    Assignee: Infacare Pharmaceutical Corporation
    Inventors: George S. Drummond, Robert Caroselli, Keith A. Cooke, Daniel Levin, David G. Roe, Christopher P. Boucher
  • METHODS FOR SYNTHESIZING METAL MESOPORPHYRINS
    Publication number: 20140228560
    Abstract: Embodiments describe methods of synthesizing metal mesoporphyrin compounds. In embodiments, a metal mesoporphyrin compound may be formed by hemin transmetallation and subsequent hydrogenation of the tin protoporphyrin IX to form a metal mesoporphyrin. In other embodiments, a method of synthesizing a metal mesoporphyrin compound comprises forming a protoporphyrin methyl ester from hemin and converting the protoporphyrin methyl ester intermediate to a metal mesoporphyrin compound through metal insertion and hydrogenation. In other embodiments, a metal mesoporphyrin compound may be formed from hemin by a hydrogen-free hydrogenation method to form a mesoporphyrin IX intermediate followed by metal insertion and hydrogenation. In embodiments, a method of synthesizing a metal mesoporphyrin compound comprises forming a mesoporphyrin IX dihydrochloride intermediate compound and converting the mesoporphyrin IX intermediate to a metal mesoporphyrin compound through metal insertion.
    Type: Application
    Filed: April 15, 2014
    Publication date: August 14, 2014
    Applicant: INFACARE PHARMACEUTICAL CORPORATION
    Inventors: Christopher P. BOUCHER, David ROE