Abstract: A tooth formation for use in a mineral processing machine is described. The tooth formation has: a pick formation comprising an elongate body comprising a shaft having at one axial end a mineral breaking pick head extending radially beyond the elongate body to define a rearwardly facing first seating surface; and a support formation defining a receiving aperture of complementary shape and size to said shaft of said elongate body so as to receive the same, and a forwardly facing second seating surface configured to abut the first seating surface of the pick formation with the shaft so received. The first and second seating surfaces comprise arrangements of one or more complementary projections and recesses radially symmetrically disposed about an axial direction of the elongate body. A mineral processing machine including at least one and preferably a plurality of tooth assemblies or tooth cap assemblies according to any preceding claim.

Abstract: A feeder (5) comprising: a feed device having: a material receiving end for receiving material; a material discharge end (11) distal of the material receiving end; an endless conveyor disposed to define a conveying surface (9) between the material receiving end and the discharge end (11) movable in use to cause material received at the material receiving end to be conveyed to the material discharge end (11), wherein the endless conveyor comprises a plurality of successively arrayed metal plates, pans or flights; a material flow monitoring device disposed in association with the feed device and adapted to obtain in use a measurement representative of a quantity of material passing along the conveying surface (9) of the endless conveyor; wherein the material flow monitoring device is adapted to obtain a measurement representative of a weight of material passing along the conveyor.

Abstract: The disclosure relates to a feeder apparatus, system and method applied to the movement of bulk material and in particular for the movement of bulk run of mine material from a working site.

Abstract: A milking apparatus is described that includes a longitudinally extending liner made from a resiliently deformable material. The liner is mounted on a rigid support shell. The liner comprises an outer hood configured to lie over an outer surface of the rigid support shell, and an inner barrel configured to be disposed within the rigid support shell and to define an internal volume. The inner barrel extends in the longitudinal direction away from an opening at a first end of the liner, through which opening an animal teat is insertable into the internal volume. The inner barrel is connected to the outer hood at a plurality of longitudinally extending connection regions on an inner surface of the outer hood. These connections define boundary conditions that limit the deformation of the barrel that encloses the teat can be set by the configuration of the liner itself.

Abstract: The present disclosure is directed to use of MrgprX2 antagonists in the treatment of inflammatory disorders, e.g., inflammatory disorders of the skin. This invention is also directed to pharmaceutical compositions comprising a MrgprX2 antagonist and a pharmaceutically or orally acceptable carrier for administration.

Abstract: The present disclosure is directed to use of MrgprX2 antagonists in the treatment of inflammatory disorders, e.g., inflammatory disorders of the skin. This invention is also directed to pharmaceutical compositions comprising a MrgprX2 antagonist and a pharmaceutically acceptable carrier for topical or oral administration.

Abstract: A material conveyor apparatus is described comprising a conveyer device having a material receiving end suitable for receiving material such as overburden or mineral at a working site, a material discharge end distal of the material receiving end, and a material transport system disposed between the material receiving end and the discharge end so as in use to cause material received at the material receiving end to be conveyed to the material discharge end; an scanning system comprising a scanning device disposed to scan the material being conveyed to the material discharge end and obtain a response from the material from which the material may be classified at least into two classes comprising at least a waste class and a useable ore class based on the response; a chassis supporting the conveyor device and the scanning device; a transport carriage supporting the chassis and adapted to cause the chassis to be movable across a surface for deployment in use.

Abstract: A milking apparatus is described that includes a longitudinally extending liner made from a resiliently deformable material. The liner is mounted on a rigid support shell. The liner comprises an outer hood configured to lie over an outer surface of the rigid support shell, and an inner barrel configured to be disposed within the rigid support shell and to define an internal volume. The inner barrel extends in the longitudinal direction away from an opening at a first end of the liner, through which opening an animal teat is insertable into the internal volume. The inner barrel is connected to the outer hood at a plurality of longitudinally extending connection regions on an inner surface of the outer hood. These connections define boundary conditions that limit the deformation of the barrel that encloses the teat can be set by the configuration of the liner itself.

Abstract: A milking apparatus is described that includes a longitudinally extending liner made from a resiliently deformable material. The liner is mounted on a rigid support shell. The liner comprises an outer hood configured to lie over an outer surface of the rigid support shell, and an inner barrel configured to be disposed within the rigid support shell and to define an internal volume. The inner barrel extends in the longitudinal direction away from an opening at a first end of the liner, through which opening an animal teat is insertable into the internal volume. The inner barrel is connected to the outer hood at a plurality of longitudinally extending connection regions on an inner surface of the outer hood. These connections define boundary conditions that limit the deformation of the barrel that encloses the teat can be set by the configuration of the liner itself.

Abstract: A feeder is described for the conveyance of material such as overburden or mineral from a working site, the feeder comprising a feed device having a material receiving end having a material receiving apron suitable for receiving material such as overburden or mineral at a working site; a material discharge end distal of the material receiving end; an endless conveyor disposed between the material receiving apron and the discharge end so as in use to cause material received at the material receiving apron to be conveyed to the material discharge end; a chassis supporting the feed device; a transport carriage supporting the chassis and adapted to cause the feeder to be movable across a surface for deployment in use. A system A system and method for the movement of material from a working site for example via transport trucks are also described.

Abstract: A milking apparatus is described that includes a longitudinally extending liner made from a resiliently deformable material. The liner is mounted on a rigid support shell. The liner comprises an outer hood configured to lie over an outer surface of the rigid support shell, and an inner barrel configured to be disposed within the rigid support shell and to define an internal volume. The inner barrel extends in the longitudinal direction away from an opening at a first end of the liner, through which opening an animal teat is insertable into the internal volume. The inner barrel is connected to the outer hood at a plurality of longitudinally extending connection regions on an inner surface of the outer hood. These connections define boundary conditions that limit the deformation of the barrel that encloses the teat can be set by the configuration of the liner itself.

Abstract: A feeder is described for the conveyance of material such as overburden or mineral from a working site, the feeder comprising a feed device having a material receiving end having a material receiving apron suitable for receiving material such as overburden or mineral at a working site; a material discharge end distal of the material receiving end; an endless conveyor disposed between the material receiving apron and the discharge end so as in use to cause material received at the material receiving apron to be conveyed to the material discharge end; a chassis supporting the feed device; a transport carriage supporting the chassis and adapted to cause the feeder to be movable across a surface for deployment in use. A system A system and method for the movement of material from a working site for example via transport trucks are also described.

Abstract: A method for estimating joint angles of a multi-segment limb from inertial sensor data accurately estimates and tracks the orientations of multiple segments of the limb as a function of time using data from a single inertial measurement unit worn at the distal end of the limb. Estimated joint angles are computed from measured inertial data as a function of time in a single step using a nonlinear state space estimator. The estimator preferably includes a tracking filter such as an unscented Kalman filter or particle filter. The nonlinear state space estimator incorporates state space evolution equations based on a kinematic model of the multi-segment limb.

Abstract: For the separation, removal, isolation, purification, characterisation, identification or quantification of fibrinogen or a protein that is a fibrinogen analogue, an affinity adsorbent is used that is a compound of formula II wherein one X is N and the other is N, C—CI or C—CN; Y is O, S or NR2; Z is O, S or NR3; R2 and R3 are each H, alkyl, hydroxyalkyl, benzyl or ?-phenylethyl; n is 0 to 6; A is a support matrix, optionally linked to the triazine ring by a spacer; R7 is a group bearing a positive charge at neutral pH; W is an optional linker; V is an aromatic group; and R8 and R9 are each H, OH, alkyl, alkoxy, amino, NH2, acyloxy, acylamino, CO2H, sulphonic acid, carbamoyl, sulphamoyl, alkylsulphonyl or halogen or a cyclic structure such as a morpholino group, or R8 and R9 are linked to form such a cyclic structure.

Abstract: Systems, servers, and methods for managing websites. Some embodiments provide methods which include, according to a user selection of a website skin, activating the selected skin. The skin comprises at least one structural box further comprising structural code for the website. The method also includes receiving a request (for instance a call to a hook) to serve the website. Further, the method includes, responsive to the request, outputting (by echoing PHP code if desired) the structural code with style related code applied thereto according to a reference between the box and a style package (which comprises the stylistic code). The outputting can occur in an order associated with the boxes. In some situations, another skin can be activated. Moreover, a change (or, perhaps, an edit) can be made to another skin and displayed without affecting the website. Moreover, another skin can be selected and associated with the website.

Abstract: A medical device for delivering RF energy to a target tissue region includes an elongate delivery cannula having a lumen in communication with a distal opening. A deployment member is positioned and longitudinally movable in the lumen. An array of electrode elements are secured to a distal end of the deployment member, the deployment member being movable from a delivery position, in which the electrode elements are positioned within the lumen, to a deployed position, in which the electrode elements extend distally out of the cannula distal opening. A sealing member formed from a bio-compatible material sufficiently rigid to penetrate solid body tissue partially extends from, and substantially seals, the distal cannula opening when the deployment member is in the delivery position.

Abstract: For the separation, removal, isolation, purification, characterization, identification or quantification of fibrinogen or a protein that is a fibrinogen analogue, an affinity adsorbent is used that is a compound of formula II wherein one X is N and the other is N, C—Cl or C—CN; Y is O, S or NR2; 0 Z is O, S or NR3; R2 and R3 are each H, alkyl, hydroxyalkyl, benzyl or &bgr; -phenylethyl; n is 0 to 6; A is a support matrix, optionally linked to the triazine ring by a spacer; R7 is a group bearing a positive charge at neutral pH; W is an optional linker; V is an aromatic group; and R8 and R9 are each H, OH, alkyl, alkoxy, amino, NH2, acyloxy, acylamino, CO2H, sulphonic acid, carbamoyl, sulphamoyl, alkylsulphonyl or halogen or a cyclic structure such as a morpholino group, or R8 and R9 are linked to form such a cyclic structure.

Abstract: Compounds of the general formula (I): in which inter alia Q1 represents —NR1R3, —OR1 or —SR1 and Q2 represents —NR2R4, —OR2 or —SR2, and A represents the point of attachment to a support matrix, are useful as protein binding ligands when (a) at least one of R1, R2, R3 and R4 includes an alkyl group —CnH2n+1 in which n is greater than or equal to 7; (b) at least two of R1, R2, R3 and R4 independently include an alkyl group —CnH2n+1 or a cycloalkyl group —CnH2n?1 in which n is greater than or equal to 4; or (c) at least three of R1, R2, R3 and R4 independently include a C1-12 alkyl group substituted by —NR5R6 or aryl.

Abstract: A medical device for delivering RF energy to a target tissue region includes an elongate delivery cannula having a lumen in communication with a distal opening. A deployment member is positioned and longitudinally movable in the lumen. An array of electrode elements are secured to a distal end of the deployment member, the deployment member being movable from a delivery position, in which the electrode elements are positioned within the lumen, to a deployed position, in which the electrode elements extend distally out of the cannula distal opening. A sealing member formed from a bio-compatible material sufficiently rigid to penetrate solid body tissue partially extends from, and substantially seals, the distal cannula opening when the deployment member is in the delivery position.

Abstract: An apparatus for delivering electrical energy includes a tubular member having a pair of opposing members extendable from the distal end of the tubular member, the opposing members being directable towards one another for engaging tissue between inner surfaces of the opposing members, the opposing members having one or more electrodes for delivering electrical energy to tissue engaged between the opposing members. One or more hollow needles extend from an inner surface of at least one opposing member, the hollow needles configured to deliver conductive fluid from a lumen into tissue penetrated by the needles.