Patents by Inventor Christopher Pigge

Christopher Pigge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dinuclear platinum(II) compounds and methods of use thereof
    Patent number: 11851447
    Abstract: The invention provides a compound of formula (Ia) or (Ib): or a salt thereof, wherein A, B, C, D, E, F, J, K, L, M, Q, V, X, Y, W and Z have any of the values described in the specification, as well as compositions comprising a compound of formula (Ia) or (Ib) or a salt thereof, and methods of use thereof.
    Type: Grant
    Filed: March 10, 2020
    Date of Patent: December 26, 2023
    Assignee: UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Christopher Pigge, Moustafa Tarek Ahmed Ibrahim Gabr
  • COMPOSITIONS FOR CHELATING METALS AT LOW TEMPERATURES
    Publication number: 20210228749
    Abstract: A method of performing a chelating reaction comprising contacting a divalent metal with a compound of Formula (I): or a salt thereof wherein: each of R1-R4 is independently selected from the group consisting of CH2COORa and CH2C(?O)NHRa; each of R5-R12 is independently selected from the group consisting of H and -L-X; each Ra is independently selected from the group consisting of H and -L-X; each L is independently selected from the group consisting of absent and a linking group; and each X is a biological agent; and wherein the contacting occurs at a temperature below about 40° C. to form a chelated composition.
    Type: Application
    Filed: April 25, 2019
    Publication date: July 29, 2021
    Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Michael K. Schultz, Christopher Pigge, Mengshi Li, Moustafa Gabr, Edwin Sagastume
  • DINUCLEAR PLATINUM(II) COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20200308208
    Abstract: The invention provides a compound of formula (Ia) or (Ib): or a salt thereof, wherein A, B, C, D, E, F, J, K, L, M, Q, V, X, Y, W and Z have any of the values described in the specification, as well as compositions comprising a compound of formula (Ia) or (Ib) or a salt thereof, and methods of use thereof.
    Type: Application
    Filed: March 10, 2020
    Publication date: October 1, 2020
    Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Christopher Pigge, Moustafa Tarek Ahmed Ibrahim Gabr
  • Image guided therapy for cancer
    Patent number: 9980951
    Abstract: The invention provides a method to treat cancer in an animal comprising administering a tetra-arylethylene cation to the animal.
    Type: Grant
    Filed: December 19, 2016
    Date of Patent: May 29, 2018
    Assignee: University of Iowa Research Foundation
    Inventors: Michael K. Schultz, Jessica Reedy, Christopher Pigge, Moustafa Tarek Ahmed Ibrahim Gabr, Mahboubeh Varmazyad, Prabhat C. Goswami
  • IMAGE GUIDED THERAPY FOR CANCER
    Publication number: 20170172991
    Abstract: The invention provides a method to treat cancer in an animal comprising administering a tetra-arylethylene cation to the animal.
    Type: Application
    Filed: December 19, 2016
    Publication date: June 22, 2017
    Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Michael K. Schultz, Jessica Reedy, Christopher Pigge, Moustafa Tarek Ahmed Ibrahim Gabr