Patents by Inventor Christopher Pirie

Christopher Pirie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for production of oxygenated terpenes
    Patent number: 11952608
    Abstract: The present invention relates to methods for producing oxygenated terpenoids. Polynucleotides, derivative enzymes, and host cells for use in such methods are also provided.
    Type: Grant
    Filed: January 5, 2021
    Date of Patent: April 9, 2024
    Assignee: Manus Bio Inc.
    Inventors: Ajikumar Parayil Kumaran, Chin Giaw Lim, Liwei Li, Souvik Ghosh, Christopher Pirie, Anthony Qualley
  • Methods for production of oxygenated terpenes
    Patent number: 11807890
    Abstract: The present disclosure relates to methods for producing oxygenated terpenoids, and preparation of compositions and formulations thereof. Polynucleotides, derivative enzymes, and host cells for use in such methods are also provided.
    Type: Grant
    Filed: November 22, 2021
    Date of Patent: November 7, 2023
    Assignees: GIVAUDAN SA, MANUS BIO INC.
    Inventors: Ajikumar Parayil Kumaran, Chin Giaw Lim, Liwei Li, Souvik Ghosh, Christopher Pirie, Anthony Qualley, Geoff Marshall-Hill, Martin Preininger
  • INCREASING PRODUCTIVITY OF E. COLI HOST CELLS THAT FUNCTIONALLY EXPRESS P450 ENZYMES
    Publication number: 20230323314
    Abstract: The present invention relates to the production of chemical species in bacterial host cells. Particularly, the present invention provides for the production of chemical species in Escherichia coli (E. coli) host cells that functionally express engineered P450 enzymes.
    Type: Application
    Filed: January 31, 2023
    Publication date: October 12, 2023
    Inventors: Jason DONALD, Christopher PIRIE, Liwei LI, Huey-Ming MAK, Srishti TIBREWALA, Ajikumar PARAYIL KUMARAN
  • METABOLIC ENGINEERING FOR MICROBIAL PRODUCTION OF TERPENOID PRODUCTS
    Publication number: 20220364127
    Abstract: In various aspects and embodiments, the invention relates to bacterial strains and methods for making terpene and terpenoid products. The invention provides bacterial strains with improved carbon flux through the MEP pathway, to thereby increase terpene and/or terpenoid product yield by fermentation with carbon sources such as glucose.
    Type: Application
    Filed: April 26, 2022
    Publication date: November 17, 2022
    Inventors: Ajikumar Parayil KUMARAN, Chin-Giaw LIM, Souvik GHOSH, Christopher PIRIE, Jason DONALD, Aaron LOVE, Hong NAN, Hsien-Chung TSENG, Christine Nicole S. SANTOS, Ryan PHILIPPE
  • Metabolic engineering for microbial production of terpenoid products
    Patent number: 11339412
    Abstract: In various aspects and embodiments, the invention relates to bacterial strains and methods for making terpene and terpenoid products. The invention provides bacterial strains with improved carbon flux through the MEP pathway, to thereby increase terpene and/or terpenoid product yield by fermentation with carbon sources such as glucose.
    Type: Grant
    Filed: April 29, 2020
    Date of Patent: May 24, 2022
    Assignee: Manus Bio Inc.
    Inventors: Ajikumar Parayil Kumaran, Chin-Giaw Lim, Souvik Ghosh, Christopher Pirie, Jason Donald, Aaron Love, Hong Nan, Hsien-Chung Tseng, Christine Nicole S. Santos, Ryan Philippe
  • METHODS FOR PRODUCTION OF OXYGENATED TERPENES
    Publication number: 20220073955
    Abstract: The present disclosure relates to methods for producing oxygenated terpenoids, and preparation of compositions and formulations thereof. Polynucleotides, derivative enzymes, and host cells for use in such methods are also provided.
    Type: Application
    Filed: November 22, 2021
    Publication date: March 10, 2022
    Inventors: Ajikumar Parayil Kumaran, Chin Giaw Lim, Liwei Li, Souvik Ghosh, Christopher Pirie, Anthony Qualley, Geoff Marshall-Hill, Martin Preininger
  • Methods for production of oxygenated terpenes
    Patent number: 11180782
    Abstract: The present disclosure relates to methods for producing oxygenated terpenoids, and preparation of compositions and formulations thereof. Polynucleotides, derivative enzymes, and host cells for use in such methods are also provided.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: November 23, 2021
    Assignees: Givaudan SA, Manus Biosynthesis, Inc.
    Inventors: Ajikumar Parayil Kumaran, Chin Giaw Lim, Liwei Li, Souvik Ghosh, Christopher Pirie, Anthony Qualley, Geoff Marshall-Hill, Martin Preininger
  • METHODS FOR PRODUCTION OF OXYGENATED TERPENES
    Publication number: 20210292798
    Abstract: The present invention relates to methods for producing oxygenated terpenoids. Polynucleotides, derivative enzymes, and host cells for use in such methods are also provided.
    Type: Application
    Filed: January 5, 2021
    Publication date: September 23, 2021
    Inventors: Ajikumar Parayil KUMARAN, Chin Giaw LIM, Liwei LI, Souvik GHOSH, Christopher PIRIE, Anthony QUALLEY
  • Methods for production of oxygenated terpenes
    Patent number: 10934564
    Abstract: The present invention relates to methods for producing oxygenated terpenoids. Polynucleotides, derivative enzymes, and host cells for use in such methods are also provided.
    Type: Grant
    Filed: August 21, 2015
    Date of Patent: March 2, 2021
    Assignee: MANUS BIO INC.
    Inventors: Ajikumar Parayil Kumaran, Chin Giaw Lim, Liwei Li, Souvik Ghosh, Christopher Pirie, Anthony Qualley
  • INCREASING PRODUCTIVITY OF E. COLI HOST CELLS THAT FUNCTIONALLY EXPRESS P450 ENZYMES
    Publication number: 20200377865
    Abstract: The present invention relates to the production of chemical species in bacterial host cells. Particularly, the present invention provides for the production of chemical species in Escherichia coli (E. coli) host cells that functionally express engineered P450 enzymes.
    Type: Application
    Filed: August 11, 2020
    Publication date: December 3, 2020
    Inventors: Jason DONALD, Christopher PIRIE, Liwei LI, Huey-Ming MAK, Srishti TIBREWALA, Ajikumar Parayil KUMARAN
  • METABOLIC ENGINEERING FOR MICROBIAL PRODUCTION OF TERPENOID PRODUCTS
    Publication number: 20200299735
    Abstract: In various aspects and embodiments, the invention relates to bacterial strains and methods for making terpene and terpenoid products. The invention provides bacterial strains with improved carbon flux through the MEP pathway, to thereby increase terpene and/or terpenoid product yield by fermentation with carbon sources such as glucose.
    Type: Application
    Filed: April 29, 2020
    Publication date: September 24, 2020
    Inventors: Ajikumar Parayil KUMARAN, Chin-Giaw LIM, Souvik GHOSH, Christopher PIRIE, Jason DONALD, Aaron LOVE, Hong NAN, Hsien-Chung TSENG, Christine Nicole S. SANTOS, Ryan PHILIPPE
  • Increasing productivity of host cells that functionally express P450 enzymes
    Patent number: 10774314
    Abstract: The present invention relates to the production of chemical species in bacterial host cells. Particularly, the present invention provides for the production of chemical species in Escherichia coli (E. coli) host cells that functionally express engineered P450 enzymes.
    Type: Grant
    Filed: August 19, 2016
    Date of Patent: September 15, 2020
    Assignee: MANUS BIO INC.
    Inventors: Jason Donald, Christopher Pirie, Liwei Li, Huey-Ming Mak, Srishti Tibrewala, Ajikumar Parayil Kumaran
  • METHODS FOR PRODUCTION OF OXYGENATED TERPENES
    Publication number: 20200224224
    Abstract: The present disclosure relates to methods for producing oxygenated terpenoids, and preparation of compositions and formulations thereof. Polynucleotides, derivative enzymes, and host cells for use in such methods are also provided.
    Type: Application
    Filed: October 30, 2019
    Publication date: July 16, 2020
    Inventors: Ajikumar Parayil Kumaran, Chin Giaw Lim, Liwei Li, Souvik Ghosh, Christopher Pirie, Anthony Qualley, Geoff Marshall-Hill, Martin Preininger
  • Metabolic engineering for microbial production of terpenoid products
    Patent number: 10662442
    Abstract: In various aspects and embodiments, the invention relates to bacterial strains and methods for making terpene and terpenoid products. The invention provides bacterial strains with improved carbon flux through the MEP pathway, to thereby increase terpene and/or terpenoid product yield by fermentation with carbon sources such as glucose.
    Type: Grant
    Filed: February 5, 2018
    Date of Patent: May 26, 2020
    Assignee: MANUS BIO INC.
    Inventors: Ajikumar Parayil Kumaran, Chin-Giaw Lim, Souvik Ghosh, Christopher Pirie, Jason Donald, Aaron Love, Hong Nan, Hsien-Chung Tseng, Christine Nicole S. Santos, Ryan Philippe
  • Methods for production of oxygenated terpenes
    Patent number: 10501760
    Abstract: The present disclosure relates to methods for producing oxygenated terpenoids, and preparation of compositions and formulations thereof. Polynucleotides, derivative enzymes, and host cells for use in such methods are also provided.
    Type: Grant
    Filed: August 21, 2015
    Date of Patent: December 10, 2019
    Assignees: GIVAUDAN SA, MANUS BIOSYNTHESIS, INC.
    Inventors: Ajikumar Parayil Kumaran, Chin Giaw Lim, Liwei Li, Souvik Ghosh, Christopher Pirie, Anthony Qualley, Geoff Marshall-Hill, Martin Preininger
  • METHODS FOR PRODUCTION OF OXYGENATED TERPENES
    Publication number: 20180327789
    Abstract: The present disclosure relates to methods for producing oxygenated terpenoids, and preparation of compositions and formulations thereof. Polynucleotides, derivative enzymes, and host cells for use in such methods are also provided.
    Type: Application
    Filed: August 21, 2015
    Publication date: November 15, 2018
    Applicants: GIVAUDAN SA, MANUS BIOSYNTHESIS, INC.
    Inventors: Ajikumar Parayil KUMARAN, Chin Giaw LIM, Liwei LI, Souvik GHOSH, Christopher PIRIE, Anthony QUALLEY, Geoff MARSHALL-HILL, Martin PREININGER
  • INCREASING PRODUCTIVITY OF E. COLI HOST CELLS THAT FUNCTIONALLY EXPRESS P450 ENZYMES
    Publication number: 20180251738
    Abstract: The present invention relates to the production of chemical species in bacterial host cells. Particularly, the present invention provides for the production of chemical species in Escherichia coli (E. coli) host cells that functionally express engineered P450 enzymes.
    Type: Application
    Filed: August 19, 2016
    Publication date: September 6, 2018
    Inventors: Jason DONALD, Christopher PIRIE, Liwei LI, Huey-Ming MAK, Srishti TIBREWALA, Ajikumar Parayil KUMARAN
  • METABOLIC ENGINEERING FOR MICROBIAL PRODUCTION OF TERPENOID PRODUCTS
    Publication number: 20180245103
    Abstract: In various aspects and embodiments, the invention relates to bacterial strains and methods for making terpene and terpenoid products. The invention provides bacterial strains with improved carbon flux through the MEP pathway, to thereby increase terpene and/or terpenoid product yield by fermentation with carbon sources such as glucose.
    Type: Application
    Filed: February 5, 2018
    Publication date: August 30, 2018
    Inventors: Ajikumar Parayil KUMARAN, Chin-Giaw LIM, Souvik GHOSH, Christopher PIRIE, Jason DONALD, Aaron LOVE, Hong NAN, Hsien-Chung TSENG, Christine Nicole S. SANTOS, Ryan PHILIPPE
  • METHODS FOR PRODUCTION OF OXYGENATED TERPENES
    Publication number: 20180135081
    Abstract: The present invention relates to methods for producing oxygenated terpenoids. Polynucleotides, derivative enzymes, and host cells for use in such methods are also provided.
    Type: Application
    Filed: August 21, 2015
    Publication date: May 17, 2018
    Inventors: Ajikumar Parayil Kumaran, Chin Giaw Lim, Liwei Li, Souvik Ghosh, Christopher Pirie, Anthony Qualley
  • Aircraft galley
    Patent number: D731396
    Type: Grant
    Filed: June 20, 2014
    Date of Patent: June 9, 2015
    Assignee: B/E Aerospace, Inc.
    Inventors: Christopher Pirie, Sebastian Petry, Michael Kemery, Aaron Hawkins, Erik Nilsen, Eddie Goh