Publication number: 20040142331
Abstract: The present invention provides purified disease detection and treatment molecule polynucleotides (mddt). Also encompassed are the polypeptides (MDDT) encoded by mddt. The invention also provides for the use of mddt, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing mddt for the expression of MDDT. The invention additionally provides for the use of isolated and purified MDDT to induce antibodies and to screen libraries of compounds and the use of anti-MDDT antibodies in diagnostic assays. Also provided are microarrays containing mddt and methods of use.
Type:
Application
Filed:
August 11, 2003
Publication date:
July 22, 2004
Inventors:
Stuart E Jackson, Stephen E Lincoln, Christina M Altus, Gerard E Dufour, Michael S Chalup, Jennier L Jackson, Anissa L Jones, Jimmy Y Yu, Rachel J Wright, Darryl Gietzen, Tommy F Liu, Pierre E Yap, Christopher R Dahl, Monika G Momiyama, Diana L Bradley, Sameer D Rohatgi, Bernard Harris, Ann M Roseberry Lincoln, Edward H Gerstin, Careyna H Peralta, Marie H David, Scott R Panzer, Vincent Z Flores, Abel Daffo, Rakesh Marwaha, Alice J Chen, Simon C Chang, Alan P Au, Rebekah R Inman
Publication number: 20030124569
Abstract: The present invention provides purified secretory polynucleotides (sptm). Also encompassed are the polypeptides (SPTM) encoded by sptm. The invention also provides for the use of sptm, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing sptm for the expression of SPTM. The invention additionally provides for the use of isolated and purified SPTM to induce antibodies and to screen libraries of compounds and the use of anti-SPTM antibodies in diagnostic assays. Also provided are microarrays containing sptm and methods of use.
Type:
Application
Filed:
August 21, 2002
Publication date:
July 3, 2003
Inventors:
Scott R. Panzer, Peter A. Spiro, Steven C. Banville, Purvi Shah, Michael S. Chalup, Simon C. Chang, Alice Chen, Steven D'sa, Stefan Amshey, Christopher R. Dahl, Tam C. Dam, Susan E. Daniels, Gerard E. Dufour, Vincent Flores, Willy T. Fong, Lila B. Greenawalt, Jennifer L. Hillman, Anissa L. Jones, Tommy F. Liu, Ann M. Roseberry, Bruce H. Rosen, Frank D. Russo, Theresa K. Stockdreher, Abel Daffo, Rachel J. Wright, Pierre E. Yap, Jimmy Y. Yu, Diana L. Bradley, Shawn R. Bratcher, Wensheng Chen, Howard J. Cohen, David M. Hodgson, Stephen E. Lincoln
