Abstract: Medical devices for cinching and cutting one or more suture, and methods for making and using such devices are disclosed. An example medical device may include a shaft, a sleeve attached to the shaft, cutter slidable within the sleeve, a cinch sleeve releasably coupled to the sleeve, and a cinch member. An elongated inner shaft may extend through and be longitudinally movable within the elongated shaft, sleeve, cutter, cinch sleeve, and cinch member. The inner shaft may be actuated to cinch and cut one or more suture disposed within the device.

Abstract: A valve assembly for a medical device including a container including a first region and a second region, a first fluid inlet fluidly coupled to the first region, a second fluid inlet fluidly coupled to the second region, and a piston assembly disposed within the container. The container is configured to house an agent within the second region, the first fluid inlet is configured to deliver a first portion of pressurized fluid to the first region at a first pressure level, and the second fluid inlet is configured to deliver a second portion of pressurized fluid to the second region at a second pressure level that is less than the first pressure level. The piston assembly includes a valve configured to move from a first position to a second position in response to the piston assembly moving relative to the container.

Abstract: A tissue fastening device includes a body including a plurality of sidewalls defining a channel, an anvil having a proximal end and a distal end and pivotally coupled to the body and the anvil moves between an open position and a closed position, and a locking mechanism to lock the anvil in the closed position.

Abstract: A suture device for use in combination with a delivery system including a lumen extending through the delivery system includes a needle usable to carry a suture, a distal shuttle configured to releasably secure the needle, a sleeve disposable over the distal shuttle, the distal shuttle movable relative to the sleeve between a locked position in which the needle is locked to the distal shuttle and an unlocked position in which the needle is releasable from the distal shuttle. A shaft is operably coupled to the sleeve and a control wire is operably coupled to the distal shuttle. A needle may include a needle cap.

Abstract: A suture device may include a suture translation assembly configured to be axially translatable within a lumen of a delivery system and a distal assembly configured to be securable to the distal end of the delivery system. The suture translation assembly and the distal assembly may cooperate to enable a user to pass a needle back and forth between the two in order to endoscopically suture a defect.

Abstract: A tissue fastening device includes a body including a plurality of sidewalls defining a channel, an anvil having a proximal end and a distal end and pivotally coupled to the body and the anvil moves between an open position and a closed position, and a locking mechanism to lock the anvil in the closed position.

Abstract: A suture device may include a suture translation assembly configured to be axially translatable within a lumen of a delivery system and a distal assembly configured to be securable to the distal end of the delivery system. The suture translation assembly and the distal assembly may cooperate to enable a user to pass a needle back and forth between the two in order to endoscopically suture a defect.

Abstract: A medical device includes an end effector at a distal end of the medical device, an actuator coupled to a proximal end of the end effector, a pivot arm pivotally coupled to the end effector distal of the proximal end of the end effector, where actuation of the actuator pivots the end effector relative to the pivot arm, and a lock on the end effector and the pivot arm, where the lock has a first state permitting the end effector to pivot relative to the pivot arm and a second state restricting the end effector from pivoting relative to the pivot arm.

Abstract: A medical device including an attachment device having a longitudinal axis, a pivot arm having a first end pivotally attached to the attachment device, an end effector pivotally attached to a second end of the pivot arm and configured to move from a first configuration to a second configuration, and a longitudinally extending body attached to a proximal end of the end effector. Movement of the longitudinally extending body in a proximal direction rotates the end effector from the first configuration to the second configuration, the end effector is approximately parallel to the longitudinal axis of the attachment device in the first configuration, and the end effector is angled relative to the longitudinal axis of the attachment device in the second configuration.

Abstract: A medical device includes an end effector at a distal end of the medical device, an actuator coupled to a proximal end of the end effector, a pivot arm pivotally coupled to the end effector distal of the proximal end of the end effector, where actuation of the actuator pivots the end effector relative to the pivot arm, and a lock on the end effector and the pivot arm, where the lock has a first state permitting the end effector to pivot relative to the pivot arm and a second state restricting the end effector from pivoting relative to the pivot arm.

Abstract: A medical device including an attachment device having a longitudinal axis, a pivot arm having a first end pivotally attached to the attachment device, an end effector pivotally attached to a second end of the pivot arm and configured to move from a first configuration to a second configuration, and a longitudinally extending body attached to a proximal end of the end effector. Movement of the longitudinally extending body in a proximal direction rotates the end effector from the first configuration to the second configuration, the end effector is approximately parallel to the longitudinal axis of the attachment device in the first configuration, and the end effector is angled relative to the longitudinal axis of the attachment device in the second configuration.

Abstract: Medical devices for cinch and cutting one or more suture, and methods for making and using such devices are disclosed. An example medical device may include a coupler, a sleeve releasably coupled to the coupler, a cutter slidably disposed within the sleeve, and a suture cinching member movable into and out of the sleeve. A wire may extend through and be longitudinally movable within the coupler to move the suture cinching member and cutter.

Abstract: Medical devices and methods of using medical devices are disclosed. An example tissue engagement device includes a first actuation member including a body coupled to a first jaw and a second jaw at a pivot point, wherein the body is designed to shift between a first configuration and a first compressed configuration and a second actuation member coupled to the first actuation member at the pivot point and at a fixation point, wherein the second actuation member is designed to shift between a second configuration and a second compressed configuration. Further, shifting the first actuation member from the first configuration to the first compressed configuration, shifting the second actuation member from the second configuration to the second compressed configuration, or both, shifts the first jaw and the second jaw between a closed configuration and an open configuration.

Abstract: Medical devices for applying a cinch to a suture and methods for making and using such devices are disclosed. An example medical device may include an elongated shaft including a proximal region and a distal region. The distal region may define a lumen having a lumen dimeter, and a distally facing end surface. The medical device may also include an outer cinch member defining a bore and having an outer surface defining a shoulder. An elongated inner shaft may extend through and be longitudinally movable within the lumen and the bore and including a distal end section. An inner cinch member may be engaged with the distal end section of the elongated inner shaft.

Abstract: Medical devices for applying a cinch to a suture and methods for making and using such devices are disclosed. An example medical device may include an elongated shaft including a proximal region and a distal region. The distal region may define a lumen having a lumen dimeter, and a distally facing end surface. The medical device may also include an outer cinch member defining a bore and having an outer surface defining a shoulder. An elongated inner shaft may extend through and be longitudinally movable within the lumen and the bore and including a distal end section. An inner cinch member may be engaged with the distal end section of the elongated inner shaft.

Abstract: A medical device includes a suture ring that defines an arcuate channel extending therein. A first arcuate needle passer is slidingly disposed within a first side of the arcuate channel and a second arcuate needle passer is slidingly disposed within a second side of the arcuate channel. A suture shuttle is passable between the first arcuate needle passer and the second arcuate needle passer and is configured to be releasably securable to the first arcuate needle passer and to the second arcuate needle passer.

Abstract: A medical device includes a mounting structure that is adapted to be secured to a distal end of an endoscope. A first suture arm is pivotably secured to the mounting structure and is adapted to releasably secure a needle that is adapted to puncture tissue while accommodating a suture. A second suture arm is pivotably secured to the mounting structure and is adapted to releasably secure the needle. The first suture arm and the second suture arm cooperate to pass the needle back and forth therebetween along an arcuate path.

Abstract: A control handle for use with a suture device operable through an endoscope includes a grip attachment configured to be secured to an endoscope and a control housing operably secured to the grip attachment. A catheter housing is moveably disposed within the control housing and adapted to releasably secure the suture catheter such that translation of the catheter housing causes translation of the suture catheter. A lever is rotatably securable relative to the catheter housing such that rotation of the lever relative to the catheter housing causes the catheter housing to move relative to the control housing. A sliding tab is disposed relative to the lever such that movement of the sliding tab relative to the lever causes the suture catheter to translate relative to the control wire disposed within the suture catheter.

Abstract: An endoscopic handle attachment is adapted to be secured to an endoscope having a working channel and used in combination with a suture device adapted to extend through the working channel. The attachment includes a backbone adapted to conform to an outer surface of the endoscope and that includes one or more attachment features adapted to enable releasable securement to the endoscope. A primary arm extends radially outwardly from the backbone and includes one or attachment points, at least one of the one or more attachment points adapted to releasably secure a proximal handle of the suture device such that a translation handle may be moved relative to the proximal handle without an operator needing to separately hold the proximal handle.

Abstract: A medical device includes a shaft including a longitudinal axis, an end effector connected to a distal end of the shaft to move from a first orientation, where a longitudinal axis of the end effector is approximately parallel to the longitudinal axis of the shaft, to a second orientation, where an angle is formed between the longitudinal axis of the end effector and the longitudinal axis of the shaft, and an elongated member attached to a proximal end of the end effector, wherein manipulation of the elongated member moves the end effector between the first orientation and the second orientation.