Abstract: This provides a system and method for analyzing and diagnosing conditions, such as cancer, based upon stained tissue sample slides prepared by users from patient tissue taken, for example, in a biopsy procedure. A convolutional neural network (CNN) is generated at training time. Slide images are acquired/scanned, and individual cell nuclei from the images are annotated, using IHC. H&E images are acquired/scanned prior to a washout intermediate step from the same slides/tissue samples. IHC is performed on the same tissue layer, which was scanned and used to retrospectively annotate the H&E WSI. IHC is used to annotate a ground truth mask for machine learning. The resultant process achieves a high degree of spatial resolution in detecting individual IHC positive nuclei, yielding process that is almost entirely automated, employing materials that are commonly available in clinical practice. In runtime, users access the CNN to perform analysis on patient slides.

Abstract: A pedestal assembly receives a pylon assembly of a tiltrotor aircraft having an airframe including a fuselage and a wing. The pedestal assembly includes inboard and outboard tip ribs that extend above the wing and respectively define inboard and outboard slots. The pedestal assembly also includes inboard and outboard bearing cartridges. The inboard bearing cartridge is received within the inboard slot, is coupled to the inboard tip rib and includes an inboard bearing assembly. The outboard bearing cartridge is received within the outboard slot, is coupled to the outboard tip rib and includes an outboard bearing assembly. The inboard and outboard bearing assemblies are operable to receive the pylon assembly therein such that the pylon assembly is rotatably mounted between the inboard and outboard tip ribs to selectively operate the tiltrotor aircraft between a helicopter mode and an airplane mode.

Abstract: A pedestal assembly for receiving a pylon assembly of a tiltrotor aircraft having a helicopter mode and an airplane mode, the tiltrotor aircraft having an airframe including a fuselage and a wing. The pedestal assembly includes an inboard pedestal supported by the airframe and positioned above the wing. The inboard pedestal includes an inboard bearing assembly disposed within an inboard pillow block housing. The pedestal assembly also includes an outboard pedestal supported by the airframe and positioned above the wing. The outboard pedestal includes an outboard bearing assembly disposed within an outboard pillow block housing. The inboard and outboard bearing assemblies are operable to receive the pylon assembly therein such that the pylon assembly is rotatably mounted between the inboard and outboard pedestals to selectively operate the tiltrotor aircraft between the helicopter mode and the airplane mode.

Abstract: A pedestal assembly for receiving a pylon assembly of a tiltrotor aircraft having a helicopter mode and an airplane mode, the tiltrotor aircraft having an airframe including a fuselage and a wing. The pedestal assembly includes an inboard pedestal supported by the airframe and positioned above the wing. The inboard pedestal includes an inboard bearing assembly disposed within an inboard pillow block housing. The pedestal assembly also includes an outboard pedestal supported by the airframe and positioned above the wing. The outboard pedestal includes an outboard bearing assembly disposed within an outboard pillow block housing. The inboard and outboard bearing assemblies are operable to receive the pylon assembly therein such that the pylon assembly is rotatably mounted between the inboard and outboard pedestals to selectively operate the tiltrotor aircraft between the helicopter mode and the airplane mode.

Abstract: A pedestal assembly receives a pylon assembly of a tiltrotor aircraft having an airframe including a fuselage and a wing. The pedestal assembly includes inboard and outboard tip ribs that extend above the wing and respectively define inboard and outboard slots. The pedestal assembly also includes inboard and outboard bearing cartridges. The inboard bearing cartridge is received within the inboard slot, is coupled to the inboard tip rib and includes an inboard bearing assembly. The outboard bearing cartridge is received within the outboard slot, is coupled to the outboard tip rib and includes an outboard bearing assembly. The inboard and outboard bearing assemblies are operable to receive the pylon assembly therein such that the pylon assembly is rotatably mounted between the inboard and outboard tip ribs to selectively operate the tiltrotor aircraft between a helicopter mode and an airplane mode.

Abstract: A propulsion system for a tiltrotor aircraft includes an engine supported by the airframe and a fixed gearbox operably coupled to the engine. Inboard and outboard pedestals are supported by the airframe and positioned above the wing. A pylon assembly is rotatably coupled between the inboard and outboard pedestals. The pylon assembly includes a spindle gearbox having an input gear, a mast operably coupled to the input gear and a proprotor assembly operable to rotate with the mast. The spindle gearbox is rotatable about a conversion axis to selectively operate the tiltrotor aircraft between helicopter and airplane modes. A common shaft, rotatable about the conversion axis, is configured to transfer torque from an output gear of the fixed gearbox to the input gear of the spindle gearbox. Each of the inboard and outboard pedestals includes a pillow block housing such as a full or a split pillow block housing.

Abstract: A propulsion system for a tiltrotor aircraft includes an engine supported by the airframe and a fixed gearbox operably coupled to the engine. Inboard and outboard tip ribs extend above the wing and define slots. Inboard and outboard bearing cartridges are received in respective slots. The inboard and outboard bearing cartridges respectively include inboard and outboard bearing assemblies. A pylon assembly is rotatably coupled between the inboard and outboard bearing assemblies. The pylon assembly includes a spindle gearbox having an input gear, a mast operably coupled to the input gear and a proprotor assembly operable to rotate with the mast. The spindle gearbox is rotatable about a conversion axis to selectively operate the tiltrotor aircraft between helicopter and airplane modes. A common shaft, rotatable about the conversion axis, is configured to transfer torque from an output gear of the fixed gearbox to the input gear of the spindle gearbox.

Abstract: A propulsion system for a tiltrotor aircraft includes an engine supported by the airframe and a fixed gearbox operably coupled to the engine. Inboard and outboard pedestals are supported by the airframe and positioned above the wing. A pylon assembly is rotatably coupled between the inboard and outboard pedestals. The pylon assembly includes a spindle gearbox having an input gear, a mast operably coupled to the input gear and a proprotor assembly operable to rotate with the mast. The spindle gearbox is rotatable about a conversion axis to selectively operate the tiltrotor aircraft between helicopter and airplane modes. A common shaft, rotatable about the conversion axis, is configured to transfer torque from an output gear of the fixed gearbox to the input gear of the spindle gearbox. Each of the inboard and outboard pedestals includes a pillow block housing such as a full or a split pillow block housing.

Abstract: A propulsion system for a tiltrotor aircraft includes an engine supported by the airframe and a fixed gearbox operably coupled to the engine. Inboard and outboard tip ribs extend above the wing and define slots. Inboard and outboard bearing cartridges are received in respective slots. The inboard and outboard bearing cartridges respectively include inboard and outboard bearing assemblies. A pylon assembly is rotatably coupled between the inboard and outboard bearing assemblies. The pylon assembly includes a spindle gearbox having an input gear, a mast operably coupled to the input gear and a proprotor assembly operable to rotate with the mast. The spindle gearbox is rotatable about a conversion axis to selectively operate the tiltrotor aircraft between helicopter and airplane modes. A common shaft, rotatable about the conversion axis, is configured to transfer torque from an output gear of the fixed gearbox to the input gear of the spindle gearbox.