Abstract: An advanced electronic disease management system is disclosed. The system has been designed to provide medical offices and hospitals with easily accessible guidelines for managing primary and secondary prevention of medical conditions, such as vascular disease. The system allows for easy integration with existing electronic data stores as well as newly entered manual and electronic records. The system is suitable for use with well-known computer interface models, and can be rapidly integrated into existing medical practices. The system can include a computer system capable of receiving a plurality of patient information inputs and a plurality of medical standards inputs, and means for comparing the patient information inputs against the medical standards inputs to produce a recommendation output.