Abstract: Disclosed herein is a 3D printing system for 3D printing batteries. The 3D printing system includes: A modular materials unit that includes multiple multi-material reservoirs that are configured to contain multiple battery materials separately. A modular printing unit with interchangeable deposition nozzles that receive material from the modular materials unit and eject the material towards a platform of the modular printing unit. A controller that selectively causes the modular materials unit to supply the multiple battery materials to the modular printing unit and the interchangeable deposition nozzles to eject the material. A power unit that supplies power to the 3D printing system. A sealed enclosure that contains the modular materials unit, the modular printing unit, the controller, and energy storage components of the power unit. And a mobility mechanism that attaches the sealed enclosure to mobility devices that can transport the 3D printing system to a desired location.

Abstract: An energy storage or electron transfer device that lacks a current collector is formed by depositing a network of conductive nanomaterials in an electrode medium to form a continuous, self-supporting mesh embedded in the electrode medium. Junctions of the deposited network of conductive nanomaterials are nanowelded to reduce junction resistance and increase mechanical cohesion. An application-specific process is performed on the welded network of conductive nanomaterials to satisfy one or more requirements for a specific application. Examples of the one or more requirements include a particular morphology, composition, or interfaces, where the application-specific process can include controlling porosity or pore size distribution, selecting or adding surface coatings, or allocating mass or thickness to maintain conductivity and performance with a target nanonetwork.

Abstract: The technology includes a method that utilizes a multi-modal printhead to deposit a first electrode material, forming an electrode layer with a defined boundary. Using a second nozzle, a thermally functional non-electrode material is deposited to create a coextensive non-electrode layer containing at least one embedded cooling channel with a tortuous path, fluidly connectable to an inlet and outlet for transporting a cooling medium. A third nozzle deposits a second electrode material, forming a second electrode layer, which may serve as either an anode or cathode. In-situ consolidation, such as laser sintering, is performed on at least one layer. The non-electrode material can be thermally conductive, insulating, or a composite, designed to dissipate heat and improve temperature uniformity. Deposition may involve extrusion, slurry-based, or inkjet methods. The cooling channel’s path length exceeds the straight-line distance between inlet and outlet, with dimensions optimized for heat removal.

Abstract: The invention relates to antibodies which bind to insulin like growth factor receptor-1 (IGF-1R) and uses thereof, in particular in the diagnosis and treatment of cancer. Specific human and murine monoclonal antibodies which inhibit IGF-1R-mediated pro-survival and tumor proliferation pathways, and variants, fragments, and derivatives thereof are provided. Also provided are specific human and murine monoclonal antibodies which block the ability of the ligands, insulin like growth factor 1 (IGF-1) and insulin like growth factor 2 (IGF-2) to bind to IGF-1R, as well as fragments, variants and derivatives of such antibodies. The invention also includes polynucleotides encoding the above antibodies or fragments, variants or derivatives thereof, as well as vectors and host cells comprising such polynucleotides. The invention further includes methods of diagnosing and treating cancer using antibodies of the invention.

Abstract: The invention relates to the three-dimensional structure of a crystal of a transporter protein complexed with a ligand. The three-dimensional structure of the transporter-ligand complex is disclosed. The transporter-ligand crystal structure, wherein the ligand is an inhibitor molecule, is useful for providing structural information that may be integrated into drug screening and drug design processes. Thus, the invention also relates to methods for utilizing the crystal structure of the transporter-ligand complex for identifying, designing, selecting, or testing inhibitors of the transporter protein, such inhibitors being useful as therapeutics for the treatment or modulation of i) diseases; ii) disease symptoms; or iii) the effect of other physiological events mediated by the transporter.

Abstract: A folding book support including a main support member having an attachment jaw which flexes to allow it to be affixed to the edge of a flat surface such as a table or desk. A pivoting cross-member is provided to extend the support diameter of the device. The cross-member is folded to a position colinear with the main support member for storage and transport. An optional support leg is provided for use when the edge of a suitable flat surface is not available to affix the holder.

Abstract: A folding book support including a main support member having an attachment jaw which flexes to allow it to be affixed to the edge of a flat surface such as a table or desk. A pivoting cross-member is provided to extend the support diameter of the device. The cross-member is folded to a position colinear with the main support member for storage and transport. An optional support leg is provided f or use when the edge of a suitable flat surface is not available to affix the holder.