Abstract: A system includes an array of chemical, pressure, and temperature sensors, and a temporal airflow modulator configured to provide sniffed vapors in a temporally-modulated sequence through a plurality of different air paths across multiple sensor locations.

Abstract: A system includes an array of chemical, pressure, and temperature sensors, and a temporal airflow modulator configured to provide sniffed vapors in a temporally-modulated sequence through a plurality of different air paths across multiple sensor locations.

Abstract: The invention provides methods for computing with chemicals by encoding digital data into a plurality of chemicals to obtain a dataset; translating the dataset into a chemical form; reading the data set; querying the dataset by performing an operation to obtain a perceptron; and analyzing the perceptron for identifying chemical structure and/or concentration of at least one of the chemicals, thereby developing a chemical computational language. The invention demonstrates a workflow for representing abstract data in synthetic metabolomes. Also presented are several demonstrations of kilobyte-scale image data sets stored in synthetic metabolomes, recovered at >99% accuracy.

Abstract: A system includes an array of chemical, pressure, and temperature sensors, and a temporal airflow modulator configured to provide sniffed vapors in a temporally-modulated sequence through a plurality of different air paths across multiple sensor locations.

Abstract: Audio signals, collected with equipment commonly available to individuals (e.g., a mobile device), can be used to analyze a patient’s breathing. An audio signal associated with the patient’s breathing for a time period can be detected with the mobile device and used to approximate the patient’s respiratory flow for the time period. For example, the audio signal can be analyzed by determining a representation of an audio frequency of the audio signal, splitting the audio frequency of the audio signal into distinct time steps, determining points comprising a weighted mean frequency at each time step, applying a frequency-to-flow rate linear transformation at each time step to approximate the respiratory flow versus time, and plotting a graphical representation of the respiratory flow versus time. The respiratory flow for the time period can be tagged with a factor related to the patient and saved in a database for future analysis.

Abstract: A system includes an array of chemical, pressure, and temperature sensors, and a temporal airflow modulator configured to provide sniffed vapors in a temporally-modulated sequence through a plurality of different air paths across multiple sensor locations.

Abstract: The invention provides methods for computing with chemicals by encoding digital data into a plurality of chemicals to obtain a dataset; translating the dataset into a chemical form; reading the data set; querying the dataset by performing an operation to obtain a perceptron; and analyzing the perceptron for identifying chemical structure and/or concentration of at least one of the chemicals, thereby developing a chemical computational language. The invention demonstrates a workflow for representing abstract data in synthetic metabolomes. Also presented are several demonstrations of kilobyte-scale image data sets stored in synthetic metabolomes, recovered at >99% accuracy.

Abstract: The invention provides methods for computing with chemicals by encoding digital data into a plurality of chemicals to obtain a dataset; translating the dataset into a chemical form; reading the data set; querying the dataset by performing an operation to obtain a perceptron; and analyzing the perceptron for identifying chemical structure and/or concentration of at least one of the chemicals, thereby developing a chemical computational language. The invention demonstrates a workflow for representing abstract data in synthetic metabolomes. Also presented are several demonstrations of kilobyte-scale image data sets stored in synthetic metabolomes, recovered at >99% accuracy.

Abstract: A method for deploying a trough structure. The methods comprise: causing a first telescoping segment to move in a first direction away from a proximal end of a telescoping boom; and transiting a flexible element from an untensioned state to a tensioned state as the first telescoping segment is moved in the first direction. The flexible element is coupled to a distal end of the first telescoping segment by a first bulkhead and is coupled to a distal end of a second telescoping segment by a second bulkhead. The first telescoping segment is coupled to the second telescoping segment of the boom when the first telescoping segment reaches an extended position. The flexible element has a parabolic trough shape when in the tensioned state.

Abstract: The invention provides methods for computing with chemicals by encoding digital data into a plurality of chemicals to obtain a dataset; translating the dataset into a chemical form; reading the data set; querying the dataset by performing an operation to obtain a perceptron; and analyzing the perceptron for identifying chemical structure and/or concentration of at least one of the chemicals, thereby developing a chemical computational language. The invention demonstrates a workflow for representing abstract data in synthetic metabolomes. Also presented are several demonstrations of kilobyte-scale image data sets stored in synthetic metabolomes, recovered at >99% accuracy.

Abstract: The invention provides methods for computing with chemicals by encoding digital data into a plurality of chemicals to obtain a dataset; translating the dataset into a chemical form; reading the data set; querying the dataset by performing an operation to obtain a perceptron; and analyzing the perceptron for identifying chemical structure and/or concentration of at least one of the chemicals, thereby developing a chemical computational language. The invention demonstrates a workflow for representing abstract data in synthetic metabolomes. Also presented are several demonstrations of kilobyte-scale image data sets stored in synthetic metabolomes, recovered at >99% accuracy.

Abstract: Systems, apparatuses, methods discussed herein provide insurance claims adjusters with the ability to quickly label numerous photographs associated with an insurance claim. For instance, a photograph label claims tool may be installed on a computing device of the insurance claims adjuster. The photograph label claims tool may facilitate labeling and formatting of photographs taken by the insurance claims adjuster of damaged property items, which may be used to settle an insurance claim. The photograph label claims tool may then generate a document (e.g., a PDF) including each of the labeled photographs and transmit the document to an insurance provider.

Abstract: A system includes an array of chemical, pressure, and temperature sensors, and a temporal airflow modulator configured to provide sniffed vapors in a temporally-modulated sequence through a plurality of different air paths across multiple sensor locations.

Abstract: A spatial distribution of cells or sub-cellular structures of a subject is quantified by receiving image data that includes a plurality of biomarkers and processing the image data to obtain a set of coordinates. Each coordinate denotes the location of a cell or sub-cellular structure represented by a biomarker or combination of biomarkers. The set of coordinates is processed into a two-dimensional symmetric matrix. Each element of the matrix indicates the frequency of a cell or sub-cellular structure represented by a first biomarker or combination of biomarkers being observed within an interaction distance of a cell or sub-cellular structure represented by a second biomarker or combination of biomarkers. A classifier assigns the subject to a group or category based on the matrix. A toxicity and/or efficacy of one or more interventions is assessed based on a comparison of the spatial distribution to one or more predetermined reference or control distributions.

Abstract: The present invention refers to the synthesis and intermediates of substituted bicyclic compounds by using a central 1H-pyrazolo[3,4-d]pyrimidine of formula (I), which is assembled starting from 4,6-dichloropyrimidine carboxylic acid. The invention in particular refers to the synthesis of the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one(ibrutinib) and its synthesis intermediates.

Abstract: Various embodiments of the invention provide a Peer-to-Peer (P2P, Internet Protocol (IP) telephone system. The telephone system includes a plurality of terminals coupled together via an IP network. The terminals cooperate with one another to provide telephony features without a dedicated central controller such as a PBX and/or a KSU controller. The terminals further cooperate with one another to maintain system-wide configuration data for the telephone system.

Abstract: In a technique for quantifying the spatial distribution of cells or sub-cellular structures, image data representing a spatial map of biomarkers is processed to obtain a set of coordinates. Each of the coordinates in the set denotes the location of a cell or sub-cellular structure represented by a biomarker or combination of biomarkers. The set of coordinates is processed into a two-dimensional symmetric (2N?1)×(2N?1) or 2N×2N matrix. The resulting matrix may be used for various purposes, such as assigning subjects clinical characteristics, and/or forming and/or testing scientific hypotheses for interventions, for example. Also described herein is an apparatus for performing the described technique.

Abstract: Various embodiments provide a Peer-to-Peer (P2P, Internet Protocol (IP) telephone system. The telephone system includes a plurality of terminals coupled together via an IP network. The terminals cooperate with one another to provide telephony features without a dedicated central controller such as a PBX and/or a KSU controller. The terminals may further receive requests for configuration data residing on other terminals, relay the requests to such other terminals to obtain the request configuration, and return the requested configuration data to the requesting device.

Abstract: Provided herein is a computer-implemented method for quantifying the spatial distribution of cells or sub-cellular structures, the method comprising the following steps performed by a computer: (a) receiving for a subject image data comprising a plurality of biomarkers, N, wherein the data represents a spatial map of the biomarkers; (b) processing the data to obtain a set of coordinates, wherein each coordinate denotes the location of a cell or sub-cellular structure represented by a biomarker or combination of biomarkers; (c) processing the set of coordinates into a two-dimensional symmetric (2N?1)×(2N?1) or 2N×2N matrix (D), wherein each element (i, j) of the matrix indicates the frequency of a cell or sub-cellular structure represented by a first biomarker or combination of biomarkers (i) being observed within an interaction distance, di, of a cell or sub-cellular structure represented by a second biomarker or combination of biomarkers (j), and wherein i and j may be the same or different; and (d) using a

Abstract: Various embodiments of the invention provide a Peer-to-Peer (P2P, Internet Protocol (IP) telephone system. The telephone system includes a plurality of terminals coupled together via an IP network. The terminals cooperate with one another to provide telephony features without a dedicated central controller such as a PBX and/or a KSU controller. The terminals further cooperate with one another to maintain system-wide configuration data for the telephone system.