Abstract: Embodiments of this invention include application of new inferential methods to analysis of complex biological information, including gene networks. New methods include modifications of Bayesian inferential methods and application of those methods to determining cause and effect relationships between expressed genes, and in some embodiments, for determining upstream effectors of regulated genes. Additional modifications of Bayesian methods include use of time course data and use of gene disruption data to infer causal relationships between expressed genes. Other embodiments include the use of bootstrapping methods and determination of edge effects to more accurately provide network information between expressed genes. Information about gene networks can be stored in a memory device and can be transmitted to an output device, or can be transmitted to remote location.

Abstract: The present invention provides therapeutic targets for antifungal treatment, especially CIK1.

Abstract: Method and agent network architecture for processing a subject message, where each agent has a view of its own domain of responsibility. An initiator agent which receives a user-input request and does not itself have a relevant interpretation policy, queries its downchain agents whether the queried agent considers such message to be in its domain of responsibility. Each queried agent recursively determines whether it has an interpretation policy of its own that applies to the request, and if not, further queries its own further downchain neighboring agents. The further agents eventually respond to such further queries, thereby allowing the first-queried agents to respond to the initiator agent. The recursive invocation of this procedure ultimately determines one or more paths through the network from the initiator agent to one more more leaf agents.

Abstract: A reversible stern drive system incorporates a continuous drive member looped about a first and second intermediate shaft and a propeller shaft to transmit rotational power from the intermediate shafts to the propeller shaft in either a first or second propeller rotational direction. Rotational direction of the propeller shaft is determined by selective coupling of either a first driven member to the first intermediate shaft by a first clutch or a second driven member to the second intermediate shaft by a second clutch. In a second embodiment of the invention, two separate continuous drive members are employed to drive two concentrically mounted propeller shafts. The first continuous drive member is looped about one of two sprockets on the first and second intermediate shafts and the first propeller shaft such that when one of the sprockets is coupled by a first clutch to the first intermediate shaft, the first propeller shaft rotates in a first propeller rotational direction.