Abstract: The present invention relates to novel peptides derived from various target proteins, complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.

Abstract: Peptides derived from Progesterone-associated endometrial protein (PAEP), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules as described. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.

Abstract: The present invention relates to novel peptides derived from Progesterone-associated endometrial protein (PAEP), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.

Abstract: Implementations of the present disclosure involve an apparatus and/or method for a regional independent tandem switch of a telecommunications network. The tandem switch processes communications between a long distance carrier and a local exchange carrier through a voice over IP (VOIP) network. By utilizing the VOIP network, the regionally independent tandem may process long distance communications to and from any point in the network, regardless of the physical proximity of the tandem to the originating/destination communication device. The regionally independent nature of the tandem also allows for flexibility in communication routing through the network, load balancing between the network tandem switches and reduction of needed components of the network for proper processing of the long distance communications.

Abstract: Implementations of the present disclosure involve an apparatus and/or method for a regional independent tandem switch of a telecommunications network. The tandem switch processes communications between a long distance carrier and a local exchange carrier through a voice over IP (VOIP) network. By utilizing the VOIP network, the regionally independent tandem may process long distance communications to and from any point in the network, regardless of the physical proximity of the tandem to the originating/destination communication device. The regionally independent nature of the tandem also allows for flexibility in communication routing through the network, load balancing between the network tandem switches and reduction of needed components of the network for proper processing of the long distance communications.

Abstract: Implementations of the present disclosure involve an apparatus and/or method for a regional independent tandem switch of a telecommunications network. The tandem switch processes communications between a long distance carrier and a local exchange carrier through a voice over IP (VOIP) network. By utilizing the VOIP network, the regionally independent tandem may process long distance communications to and from any point in the network, regardless of the physical proximity of the tandem to the originating/destination communication device. The regionally independent nature of the tandem also allows for flexibility in communication routing through the network, load balancing between the network tandem switches and reduction of needed components of the network for proper processing of the long distance communications.

Abstract: Implementations of the present disclosure involve an apparatus and/or method for a regional independent tandem switch of a telecommunications network. The tandem switch processes communications between a long distance carrier and a local exchange carrier through a voice over IP (VOIP) network. By utilizing the VOIP network, the regionally independent tandem may process long distance communications to and from any point in the network, regardless of the physical proximity of the tandem to the originating/destination communication device. The regionally independent nature of the tandem also allows for flexibility in communication routing through the network, load balancing between the network tandem switches and reduction of needed components of the network for proper processing of the long distance communications.

Abstract: Implementations of the present disclosure involve an apparatus and/or method for a regional independent tandem switch of a telecommunications network. The tandem switch processes communications between a long distance carrier and a local exchange carrier through a voice over IP (VOIP) network. By utilizing the VOIP network, the regionally independent tandem may process long distance communications to and from any point in the network, regardless of the physical proximity of the tandem to the originating/destination communication device. The regionally independent nature of the tandem also allows for flexibility in communication routing through the network, load balancing between the network tandem switches and reduction of needed components of the network for proper processing of the long distance communications.

Abstract: Implementations of the present disclosure involve an apparatus and/or method for a regional independent tandem switch of a telecommunications network. The tandem switch processes communications between a long distance carrier and a local exchange carrier through a voice over IP (VOIP) network. By utilizing the VOIP network, the regionally independent tandem may process long distance communications to and from any point in the network, regardless of the physical proximity of the tandem to the originating/destination communication device. The regionally independent nature of the tandem also allows for flexibility in communication routing through the network, load balancing between the network tandem switches and reduction of needed components of the network for proper processing of the long distance communications.

Abstract: A method of knitting is performed by a knitting machine having two needle beds and double-ended needles transferable between the two beds, for knitting a ventilated garment panel in which a ventilation channel is formed as part of the base knitted structure. The final article is knitted in one piece. The part of the garment incorporating the ventilation channel is knitted as a three-layer fabric so that the ventilation channel formed by two side walls and one front wall is open to the inside of the garment panel through a wale-wise opening and to the outside of the garment panel at the ends of the ventilation panel.

Abstract: The present invention is concerned with methods for improved production of reticuline. More particularly, the present invention relates to the use of a mutagenized Papaver somniferum poppy plant to produce (S)-reticuline in higher yield. The invention also relates to methods for extracting and purifying reticuline.