Abstract: A sanitary cabin has at least one floor part, at least one ceiling part and a plurality of side-wall parts. At least one waste-holding tank is also provided. At least one sanitary installation is disposed in the sanitary cabin. In addition, the sanitary cabin has at least one collection tank in which the waste water from the at least one sanitary installation can be collected. The waste water collected in the collection tank can be transferred as a liquid supply into the waste-holding tank during maintenance or cleaning of the sanitary cabin.

Abstract: 1. A vehicle system for controlling operation of a vehicle includes one or more processing circuits configured to set a pre-calibrated value of a steering input device of the vehicle as a center value, the steering input device configured to receive an input from an operator to steer one or more tractive elements of the vehicle, monitor a precheck condition regarding an operational characteristic of the vehicle associated with a straight-line travel of the vehicle, control, in response to the precheck condition not being satisfied for a threshold time, an operation of the vehicle, and update, in response to the precheck condition being satisfied for the threshold time, the center value to be a current steering position value of the steering input device.

Abstract: The present invention is directed to compositions and methods of treating or preventing diseases or disorders with inhibitors of SHP2, alone, and in combination with other therapeutic agents such as RAS pathway inhibitors (e.g., MEK inhibitors); methods of establishing appropriate treatment plans for subjects based upon the expression of one or more biomarker indicative of SHP2 inhibitor sensitivity; and methods of determining sensitivity to a SHP2 inhibitor based on a phosphorylation status of SHP2.

Abstract: The present invention is directed to compositions and methods of treating or preventing diseases or disorders with inhibitors of SHP2, alone, and in combination with other therapeutic agents such as RAS pathway inhibitors (e.g., MEK inhibitors); methods of establishing appropriate treatment plans for subjects based upon the expression of one or more biomarker indicative of SHP2 inhibitor sensitivity; and methods of determining sensitivity to a SHP2 inhibitor based on a phosphorylation status of SHP2.

Abstract: The present invention is directed to compositions and methods of treating or preventing diseases or disorders with inhibitors of SHP2, alone, and in combination with other therapeutic agents such as RAS pathway inhibitors (e.g., MEK inhibitors); methods of establishing appropriate treatment plans for subjects based upon the expression of one or more biomarker indicative of SHP2 inhibitor sensitivity; and methods of determining sensitivity to a SHP2 inhibitor based on a phosphorylation status of SHP2.

Abstract: The present invention is directed to compositions and methods of treating or preventing diseases or disorders with inhibitors of SHP2, alone, and in combination with other therapeutic agents such as RAS pathway inhibitors (e.g., MEK inhibitors); methods of establishing appropriate treatment plans for subjects based upon the expression of one or more biomarker indicative of SHP2 inhibitor sensitivity; and methods of determining sensitivity to a SHP2 inhibitor based on a phosphorylation status of SHP2.

Abstract: A torch extender for a plasma arc cutting system is provided. The plasma torch extender includes an elongated substantially dielectric body that defines a first end and a second end and includes a flexible section that is poseable across a plurality of orientations. The torch extender also includes a first connector, at the first end of the elongated substantially dielectric body, which mates with a consumable set, and a second connector, at the second end of the elongated substantially dielectric body, which mates with a torch mount. The torch extender further includes a consumable detection medium that communicates the presence of the consumable set. The consumable detection medium is disposed within the elongated substantially dielectric body and extends between the first end and the second end of the elongated substantially dielectric body.

Abstract: A torch extender for a plasma arc cutting system is provided. The plasma torch extender includes an elongated substantially dielectric body that defines a first end and a second end and includes a flexible section that is poseable across a plurality of orientations. The torch extender also includes a first connector, at the first end of the elongated substantially dielectric body, which mates with a consumable set, and a second connector, at the second end of the elongated substantially dielectric body, which mates with a torch mount. The torch extender further includes a consumable detection medium that communicates the presence of the consumable set. The consumable detection medium is disposed within the elongated substantially dielectric body and extends between the first end and the second end of the elongated substantially dielectric body.