Abstract: The present invention relates to a compound of the formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, A, X, n, and are as defined herein. Such novel benzamidazole derivatives are useful in trv treatment of abnormal cell growth, such as cancer, in mammals. This invention ate relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing sue compounds.

Abstract: An energy delivering probe is used for thermally coagulating and/or constricting hollow anatomical structures (HAS) including, but not limited to, blood vessels such as perforator veins. The probe includes a shaft and at least two electrodes where at least one of the electrodes has a perimeter that increases as it extends proximally.

Abstract: A pulse response for a receiver, as an array PR, is found from the receiver's symbol stream. For a continuous stream of arbitrary data, a value of the array PR[k] can be determined from the signal levels of the symbols received. The stream of received data is input to a FIFO. Between the first and last locations of the FIFO is the symbol referred to herein as Dn. Symbols located in the FIFO before Dn are referred to as Dn?x. Symbols located in the FIFO after Dn are referred to as Dn+x. Dn differs from the other FIFO symbols in that its signal level can be measured with an adjustable error slicer. The ISI effect of any Dn?k upon Dn can be measured, and thus any PR[k] measured, by measuring the average signal level of Dn when only certain types of data streams occur in the FIFO.

Abstract: A pulse response for a receiver, as an array PR, is found from the receiver's symbol stream. For a continuous stream of arbitrary data, a value of the array PR[k] can be determined from the signal levels of the symbols received. The stream of received data is input to a FIFO. Between the first and last locations of the FIFO is the symbol referred to herein as Dn. Symbols located in the FIFO before Dn are referred to as Dn?x. Symbols located in the FIFO after Dn are referred to as Dn+x. Dn differs from the other FIFO symbols in that its signal level can be measured with an adjustable error slicer. The ISI effect of any Dn?k upon Dn can be measured, and thus any PR[k] measured, by measuring the average signal level of Dn when only certain types of data streams occur in the FIFO.

Abstract: A gastric balloon includes a scaffold structure, one or more internal inflatable compartments within the scaffold structure, and one or more inflatable bladders formed over the space-filling compartment. The gastric balloon may be deployed transesophageally using a gastroscope and is inflated in situ, preferably using a combination of liquid and gas inflation media.

Abstract: A functional block under test (FBUT), comprising mixed-signal or analog circuits, can be tested by a digital test machine (DTM). A DTM sources test vectors to, and expects to receive certain vectors back from, a DUT. The DUT is a single, physically contiguous, IC upon which is integrated the FBUT, a mixed-signal generate and capture unit (MSGC) and a control system. The test vectors can include computer programs for instructing the control system on how to perform mixed-signal or analog-domain tests of the FBUT using resources of the MSGC (such as DACs and ADCs). The test vectors can also include data that effects the operation of a parameterized test procedure, where the test procedure is part of the control system. The control system, in accordance with the test procedure, uses the MSGC to perform mixed-signal or analog-domain tests of the FBUT. The FBUT can include an analog test bus.

Abstract: An electrosurgical device comprising an elongate probe member having proximal and distal extremities and a passage extending from the proximal extremity to an opening at the distal extremity. The elongate probe member is provided with an elongate cutout adjacent the opening so that the elongate probe member is formed with an elongate extension projecting alongside the cutout beyond the opening. A guide canula is mounted in the passage of the elongate probe member and has proximal and distal extremities and a lumen extending therethrough. A radio frequency electrode is disposed in the lumen and an insulating sleeve is coaxially disposed on the radio frequency electrode. A handle is secured to the proximal extremity of the guide canula for advancing and retracting the radio frequency electrode and the insulating sleeve with respect to the guide canula and for causing bending of the distal extremity of the guide cannula into the cutout.

Abstract: An electrosurgical device for medical treatment of tissue at a treatment site through a body opening. The device includes a sheath having proximal and distal extremities and having a passageway extending from the proximal extremity to the distal extremity. A guide tube is slidably mounted in the passageway of the sheath and has proximal and distal extremities and a lumen extending from the proximal extremity to the distal extremity. A needle electrode is slidably mounted in the lumen of the guide tube and has proximal and distal extremities. Insulation is coaxially disposed on the needle electrode. A handle adapted to be gripped by the human hand is provided and the proximal extremity of the guide tube is mounted on the handle. An assembly is carried by the handle for bending the distal extremity of the guide tube at an angle with respect to the longitudinal axis. The needle electrode is adapted to be coupled to an energy source.

Abstract: An inventive surgical handpiece comprises a handle unit and structure carried by the handle unit for engaging a patient. A hand actuable element is mounted for rotation on the handle unit, about first and second mutually transverse axes. A first mechanism is responsive to rotation of the hand actuable element about its first axis for imparting first degree of freedom movement to the patient engaging structure. A second mechanism is responsive to rotation of the same hand actuable element about its second axis for imparting second degree of freedom movement to the patient engaging structure.