Abstract: A tension rod storage kit, comprising a tension rod, a tray and an optional pouch, and a plurality of attachment means for securing the kit to two parallel walls and, optionally, to one wall perpendicular to both of the parallel walls.

Abstract: The surgical bone clamp securely grasps and removes bone and other tissue during surgery, such as total knee replacement surgery. In one embodiment, the device includes a handle portion, a clamp portion, and a ratchet portion. The handle portion includes two handle arms that are pivotally connected, and the ratcheting portion permits the handle arms to be spaced at any one of a plurality of step settings. One of the handle arms provides a finger loop to engage the thumb, while the other handle arm provides a finger loop to engage at least one opposing finger. The clamp portion includes two serrated clamping jaws designed to engage the bone or other tissue surface and to provide adequate gripping force to allow for removal of the bone piece or tissue from the body cavity. The device provides significant mechanical advantage to the user, may be operated with one hand, and may include removable clamping jaws.

Abstract: The invention provides a nucleic acid molecule encoding a growth hormone (GH) which the RSP sorting signal has been mutated, such that the GH can be constitutively secreted by the nonregulated secretory pathway (NRSP) in a mammalian cell.

Abstract: The invention discloses cathepsin S as a suitable target for the development of new therapeutics to treat or ameliorate chronic pain. The invention relates to methods to treat and/or ameliorate chronic pain and pharmaceutical compositions therefor comprising modulators with inhibitory effect on cathepsin S enzyme activity and/or cathepsin S gene expression. The invention also relates to a method to identify compounds with therapeutic usefulness to treat chronic pain, comprising identifying compounds that can inhibit cathepsin S activity and/or gene expression which can also reverse the pathological effects of chronic pain in vivo.

Abstract: The invention relates to pyrrolo pyrimidines of formula (I), wherein Y represents —(CH2)t—O— or —(CH2)r—S—, p is 1 or 2, r is 1, 2 or 3, t is 1, 2 or 3, or Y is —(CH2)j— or —CH?CH—, j is 1 or 2; p is 1 or 2, or Y is —(CH2)f—, f is 1 or 2, p is 1, and the further radicals and symbols have the meaning as defined herein; their preparation, their use as pharmaceuticals, pharmaceutical compositions containing them, the use of such a compound for the manufacture of a pharmaceutical preparation for the treatment of neuropathic pain and to a method for the treatment of such a disease in animals, especially in humans.