Patents by Inventor Christopher Stimson

Christopher Stimson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Carboxylic acid aromatic amides
    Patent number: 12023319
    Abstract: The present invention relates to carboxylic acid aromatic amides compounds of general formula (I) as described and defined herein, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease as a sole agent or in combination with other active ingredients.
    Type: Grant
    Filed: September 17, 2021
    Date of Patent: July 2, 2024
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Stefan Bäurle, Adam James Davenport, Christopher Stimson, Jens Nagel, Nicole Schmidt, Andrea Rotgeri, Ina Gröticke, Alexandra Rausch, Juergen Klar, Thomas Dyrks
  • Carboxylic acid aromatic amides as antagonists of bradykinin B1 receptor
    Patent number: 11905270
    Abstract: The present invention relates to carboxylic acid aromatic amides compounds of general formula (I) as described and defined herein, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a diseaseas a sole agent or in combination with other active ingredients.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: February 20, 2024
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Stefan Baeurle, Adam James Davenport, Christopher Stimson, Jens Nagel, Nicole Schmidt, Andrea Rotgeri, Ina Groeticke, Alexandra Rausch, Juergen Klar, Thomas Dyrks
  • CARBOXYLIC ACID AROMATIC AMIDES AS ANTAGONISTS OF BRADYKININ B1 RECEPTOR
    Publication number: 20230271931
    Abstract: The present invention relates to carboxylic acid aromatic amides compounds of general formula (I) as described and defined herein, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a diseases a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: April 7, 2023
    Publication date: August 31, 2023
    Inventors: Stefan BAEURLE, Adam DAVENPORT, Christopher STIMSON, Jens NAGEL, Nicole SCHMIDT, Andrea ROTGERI, Ina GROETICKE, Alexandra RAUSCH, Juergen KLAR, Thomas DYRKS
  • CARBOXYLIC ACID AROMATIC AMIDES
    Publication number: 20230086179
    Abstract: The present invention relates to carboxylic acid aromatic amides compounds of general formula (I) as described and defined herein, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: December 18, 2017
    Publication date: March 23, 2023
    Inventors: Stefan BAEURLE, Adam James DAVENPORT, Christopher STIMSON, Jens NAGEL, Nicole SCHMIDT, Andrea ROTGERI, Ina GROETICKE, Alexandra RAUSCH, Juergen KLAR, Thomas DYRKS
  • CARBOXYLIC ACID AROMATIC AMIDES
    Publication number: 20230043209
    Abstract: The present invention relates to carboxylic acid aromatic amides compounds of general formula (I) as described and defined herein, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: September 17, 2021
    Publication date: February 9, 2023
    Inventors: Stefan BAEURLE, Adam James DAVENPORT, Christopher STIMSON, Jens NAGEL, Nicole SCHMIDT, Andrea ROTGERI, Ina GROETICKE, Alexandra RAUSCH, Juergen KLAR, Thomas DYRKS
  • PYRIDINE DERIVATIVES AS TMEM16A MODULATORS FOR USE IN THE TREATMENT OF RESPIRATORY CONDITIONS
    Publication number: 20220235006
    Abstract: Compounds of general formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 are as defined herein are useful for treating respiratory disease and other diseases and conditions modulated by TMEM16A.
    Type: Application
    Filed: January 21, 2022
    Publication date: July 28, 2022
    Inventors: Stephen COLLINGWOOD, Craig BUXTON, Jonathan David HARGRAVE, Peter INGRAM, Thomas Beauregard SCHOFIELD, Abdul SHAIKH, Christopher STIMSON
  • PYRIDINE DERIVATIVES AS CALCIUM-ACTIVATED CHLORIDE CHANNEL MODULATORS
    Publication number: 20220144803
    Abstract: Compounds of general formula (I), wherein R1, R2, R3, R4, R5, X1, X2 and X3 are as defined herein are useful for treating respiratory disease and other diseases and conditions modulated by TMEM16A.
    Type: Application
    Filed: January 21, 2022
    Publication date: May 12, 2022
    Inventors: Stephen COLLINGWOOD, Craig BUXTON, Matthew HABGOOD, Jonathan David HARGRAVE, Thomas Beauregard SCHOFIELD, Matthew SMITH, Christopher STIMSON
  • COMPOUNDS FOR TREATING RESPIRATORY DISEASE
    Publication number: 20220098167
    Abstract: Compounds of general formula (I) and their tautomeric forms all enantiomers and isotopic variants and salts and solvates thereof: wherein represents a single or a double bond and R1, R2, X1, X2, X3, X4, X5, Y and Z are as defined herein; are useful for treating respiratory disease and other diseases and conditions modulated by TMEM16A.
    Type: Application
    Filed: December 10, 2021
    Publication date: March 31, 2022
    Inventors: Stephen COLLINGWOOD, Clive MCCARTHY, Duncan Alexander HAY, Jonathan David HARGRAVE, Albert MA, Thomas Beauregard SCHOFIELD, Matthew SMITH, Edward WALKER, Naomi WENT, Peter INGRAM, Christopher STIMSON, Someina KHOR
  • TETRAZOLE CONTAINING COMPOUNDS
    Publication number: 20210317092
    Abstract: The present invention relates to tetrazole containing compounds of general formula (I) as described and defined herein, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease syndrome, condition, or symptoms, in particular related to chronic pain and inflammation, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: December 18, 2017
    Publication date: October 14, 2021
    Inventors: Stefan BÄEURLE, Adam James DAVENPORT, Christopher STIMSON, James Lindsay CARR, Christian Abingdon BUBERT, Frédéric Jacques MARLIN, Jens NAGEL, Nicole SCHMIDT, Andrea ROTGERI, Horst IRLBACHER
  • Compounds
    Publication number: 20200383988
    Abstract: Compounds of general formula (1): wherein R1, R2, R3, R4, R5a, R* X1, X2, Z and Y are as defined herein are positive modulators of the N H calcium-activated chloride channel (CaCC), TMEM16A. The compounds are useful for treating diseases and conditions affected by modulation of TMEM16A, particularly respiratory diseases and conditions.
    Type: Application
    Filed: November 22, 2019
    Publication date: December 10, 2020
    Inventors: Stephen Collingwood, Clive Mccarthy, Jonathan David Hargrave, Duncan Alexander Hay, Thomas Beauregard Schofield, Sarah Ellam, Craig Buxton, Matthew Habgood, Peter Ingram, Chun Yan Ma, Spencer Napier, Abdul Shaikh, Matthew Smith, Christopher Stimson, Edward Walker
  • COMPOUNDS
    Publication number: 20200361871
    Abstract: Compounds of general formula (I): wherein R1, R2, R3, R4, R5a, R5b X1, X2, Z and Y are as defined herein are positive modulators of the calcium-activated chloride channel (CaCC), TMEM16A. The compounds are useful for treating diseases and conditions affected by modulation of TMEM16A, particularly respiratory diseases and conditions.
    Type: Application
    Filed: July 30, 2020
    Publication date: November 19, 2020
    Inventors: Stephen Collingwood, Clive Mccarthy, Jonathan David Hargrave, Duncan Alexander Hay, Thomas Beauregard Schofield, Sarah Ellam, Craig Buxton, Matthew Habgood, Peter Ingram, Chun Yan Ma, Spencer Napier, Abdul Shaikh, Matthew Smith, Christopher Stimson, Edward Walker