Patents by Inventor Christopher Straub

Christopher Straub has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dimeric IAP inhibitors
    Patent number: 8445440
    Abstract: The present invention provides compounds of formula M-L-M? (where M and M? are each independently a monomeric moiety of Formula (I) and L is a linker). The dimeric compounds have been found to be effective in promoting apoptosis in rapidly dividing cells.
    Type: Grant
    Filed: February 23, 2011
    Date of Patent: May 21, 2013
    Assignee: Novartis AG
    Inventors: Christopher Straub, Zhuoliang Chen, Mark Palermo
  • Inhibitors of IAP
    Publication number: 20120207769
    Abstract: Novel compounds that inhibit the binding of the Smac protein to Inhibitor of Apoptosis Proteins (IAPs) of the formula (I).
    Type: Application
    Filed: April 26, 2012
    Publication date: August 16, 2012
    Applicant: NOVARTIS AG
    Inventors: Mark G. PALERMO, Sushil Kumar SHARMA, Christopher STRAUB, Run-Ming WANG, Leigh ZAWEL, Yanlin ZHANG, Zhuoliang CHEN, Yaping WANG, Fan YANG, Wojciech WRONA, Gang LIU, Mark G. CHAREST, Feng HE
  • Inhibitors of IAP
    Publication number: 20110281875
    Abstract: Novel compounds that inhibit the binding of the Smac protein to Inhibitor of Apoptosis Proteins (IAPs) of the formula (I).
    Type: Application
    Filed: July 8, 2011
    Publication date: November 17, 2011
    Inventors: Mark G. PALERMO, Sushil Kumar SHARMA, Christopher STRAUB, Run-Ming WANG, Leigh ZAWEL, Yanlin ZHANG, Zhuoliang CHEN, Yaping WANG, Fan YANG, Wojciech WRONA, Gang LIU, Mark G. CHAREST, Feng HE
  • 2-Aminocarbonyl Substituted Piperazine or Diaza-Cyclic Compounds as Apoptosis Protein Inhibitors (Iap) Modulators
    Publication number: 20110183955
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, solvates, hydrates or pharmaceutically acceptable formulations thereof. These compounds may be used to modulate cellular proliferation and to prevent and/or treat proliferative diseases.
    Type: Application
    Filed: March 21, 2011
    Publication date: July 28, 2011
    Applicant: NOVARTIS AG
    Inventors: Robert ECKL, Roswitha TAUBE, Michael ALMSTETTER, Michael THORMANN, Andreas TREML, Christopher STRAUB, Zhuoliang CHEN
  • 2-aminocarbonyl substituted piperazine or diaza-cyclic compounds as apoptosis protein inhibitors (lap) modulators
    Patent number: 7932255
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, solvates, hydrates or pharmaceutically acceptable formulations thereof. These compounds may be used to modulate cellular proliferation and to prevent and/or treat proliferative diseases.
    Type: Grant
    Filed: April 13, 2006
    Date of Patent: April 26, 2011
    Assignee: Novartis AG
    Inventors: Robert Eckl, Roswitha Taube, Michael Almstetter, Michael Thormann, Andreas Treml, Christopher Straub, Zhouliang Chen
  • Organic Compounds
    Publication number: 20110065726
    Abstract: The present invention is directed to a compound of the formula: or pharmaceutically acceptable salts thereof and use of such compounds for treating proliferative diseases such as cancer, in mammals.
    Type: Application
    Filed: July 31, 2007
    Publication date: March 17, 2011
    Inventors: Zhuoliang CHEN, Sushil Kumar Sharma, Christopher Straub, Mark G. Charest, Feng He, Run-Ming David Wang, Leigh Zawel, Christine Hiu-Tung Chen, Miao Dai, Huangshu Lei, Ly Pham, Fan Yang
  • Pyrrolydine Derivatives as IAP Inhibitors
    Publication number: 20110015232
    Abstract: The present invention relates to novel IAP inhibitor compounds of: Formula (I).
    Type: Application
    Filed: October 10, 2007
    Publication date: January 20, 2011
    Inventors: Mark G. Charest, Christine Hiu-Tung CHEN, Ming Chen, Zhuoliang Chen, Miao Dai, Feng He, Huangshu Lei, Christopher Straub, Run-Ming David Wang, Leigh Zawel
  • Inhibitors of Iap
    Publication number: 20080242658
    Abstract: Novel compounds that inhibit the binding of the Smac protein to Inhibitor of Apoptosis Proteins (IAPs) of the formula I
    Type: Application
    Filed: April 6, 2005
    Publication date: October 2, 2008
    Inventors: Mark G Palermo, Sushil Kumar Sharma, Christopher Straub, Run-Ming Wang, Leigh Zawel, Yanlin Zhang, Zhuoliang Chen, Yaping Wang, Fan Yang, Wojciech Wrona, Gang Liu, Mark G. Charest, Feng He
  • Organic compounds
    Patent number: 7419975
    Abstract: Novel compounds that inhibit the binding of the Smac protein to Inhibitor of Apoptosis Proteins (IAPs) of the formula I
    Type: Grant
    Filed: April 6, 2005
    Date of Patent: September 2, 2008
    Assignee: Novartis AG
    Inventors: Mark Gabriel Palermo, Sushil Kumar Sharma, Christopher Straub, Run-Ming Wang, Leigh Scott Zawel, Yanlin Zhang, Zhuoliang Chen, Yaping Wang, Fan Yang, Wojciech Wrona, Gang Liu, Mark G. Charest, Feng He
  • 2-Aminocarbonyl Substituted Piperazine or Diaza-Cyclic Compounds as Apoptosis Protein Inhibitors (Iap) Modulators
    Publication number: 20080207630
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, solvates, hydrates or pharmaceutically acceptable formulations thereof. These compounds may be used to modulate cellular proliferation and to prevent and/or treat proliferative diseases.
    Type: Application
    Filed: April 13, 2006
    Publication date: August 28, 2008
    Inventors: Robert Eckl, Roswitha Taube, Michael Almstetter, Michael Thormann, Andreas Treml, Christopher Straub, Zhuoliang Chen
  • Organic compounds
    Publication number: 20050234042
    Abstract: Novel compounds that inhibit the binding of the Smac protein to Inhibitor of Apoptosis Proteins (IAPs) of the formula I
    Type: Application
    Filed: April 6, 2005
    Publication date: October 20, 2005
    Inventors: Mark Palermo, Sushil Sharma, Christopher Straub, Run-Ming Wang, Leigh Zawel, Yanlin Zhang, Zhuoliang Chen, Yaping Wang, Fan Yang, Wojciech Wrona, Gang Liu, Mark Charest, Feng He