Abstract: Organs-on-chips are microfluidic devices for culturing living cells in micrometer sized chambers in order to model physiological functions of tissues and organs. Engineered patterning and continuous fluid flow in these devices has allowed culturing of intestinal cells bearing physiologically relevant features and sustained exposure to bacteria while maintaining cellular viability, thereby allowing study of inflammatory bowl diseases. However, existing intestinal cells do not possess all physiologically relevant subtypes, do not possess the repertoire of genetic variations, or allow for study of other important cellular actors such as immune cells. Use of iPSC-derived epithelium, including IBD patient-specific cells, allows for superior disease modeling by capturing the multi-faceted nature of the disease.

Abstract: New ways of presenting information in a web browser are presented wherein documents categorized as belonging to the same web site or application are grouped together and presented in either an first mode where a browser window is open and one of the resources categorized as belonging to the group is displayed, or in a second mode where the group is represented by an icon.

Abstract: New ways of presenting information in a web browser are presented wherein documents categorized as belonging to the same web site or application are grouped together and presented in either an first mode where a browser window is open and one of the resources categorized as belonging to the group is displayed, or in a second mode where the group is represented by an icon.

Abstract: The invention is directed to a method, computer system, and computer program for providing grouped tabs in a web browser. When multiple web pages are open in multiple tabs, a user initiated event indicating the creation of a group of tabs can be detected and at least two tabs may be associated with the created group. A group tab representing the group of tabs can then be displayed in place of all the individual tabs.

Abstract: The invention is directed to a method, computer system, and computer program for providing a user feedback regarding available mouse gestures. Each of the mouse gestures comprises a predetermined sequence of one or more mouse movements, and corresponds to a predetermined action or command. After the gesture is initiated, the feedback is provided to the user when a predetermined timer expires since the user initiated the gesture or the last mouse movement. This allows for feedback to be provided to users who get lost mid-gesture, without providing unnecessary feedback to a more experienced user who is able to quickly perform the gesture. The feedback can instruct the user as to each available gesture, along with the corresponding action or command.