Abstract: The present invention provides methods for screening and diagnosing prostate cancer based on a correlation between cancer cell growth, cancer lethality or recurrence and the expression level of ZFP36 or NEDD9 and PTEN in conjunction with ZFP36. The disclosure also provides methods for screening and diagnosing prostate cancer based on a correlation between cancer lethality and the genotype of rs1910301 SNP. Also provided are methods for treating prostate cancer comprising providing a treatment or monitoring based on the expression level of ZFP36, the expression level of NEDD9, and the expression level of ZFP36 in conjunction with PTEN levels or the genotype of rs1910301 SNP.

Abstract: A vertical door latch assembly includes a housing and a bolt movably attached to the housing having a catch portion. A drive motor is located within the housing and is configured to selectively move a lock assembly between a locked position preventing movement of the bolt and an unlocked position allowing movement of the bolt. A controller is in electrical communication with the drive motor and is configured to direct the actuator lock assembly between the locked position and the unlocked position. A force sensor is in electrical communication with the controller configured to measured when a force exceeds a predetermined threshold.

Abstract: This disclosure includes an expansion driver for adjusting expandable implants, the expansion driver including an input shaft operably connected to at least one bevel gear, the at least one bevel gear configured to engage each of a first gear and a second gear; the first gear connected to a first output shaft, the first output shaft terminating in a first driver configured to communicate with a first actuator of an expandable implant; the second gear connected to a second output shaft, the second output shaft annularly disposed around at least a portion of the first output shaft; and at least one pinion configured to transfer a torque from the second output shaft to a second driver extending parallel to the first driver and configured to communicate with a second actuator of the expandable implant. Upon a rotation of the input shaft, a torque is applied to at least one of the first driver and the second driver.

Abstract: A vertical door latch assembly includes a housing and a bolt movably attached to the housing having a catch portion. A drive motor is located within the housing and is configured to selectively move a lock assembly between a locked position preventing movement of the bolt and an unlocked position allowing movement of the bolt. A battery assembly is removable from the housing when the lock assembly is in first position and fixed to the housing when the lock assembly is in a second position. A controller is in electrical communication with the drive motor and is configured to direct the actuator lock assembly between the locked position and the unlocked position.

Abstract: Systems and methods are provided for configuring automatic playback settings on a media playback device. A graphical user interface displays automatic playback settings and receives selections of customized settings for automatic playback. The settings can include context granularity for automatic playback, limiting autoplay to when the media playback device is connected to a wireless network, and activating an audible notification when automatic playback of media content is beginning. An initial queue of media content is selected for playback on the media playback device. The system ascertains whether autoplay is enabled for a particular situation. If autoplay is enabled, the system automatically generates a queue of media that is related to the initial queue and initiates playback on the media playback device after the initial queue concludes.

Abstract: Systems and methods are provided to create training data, validate, deploy and test artificial intelligence (AI) systems in a virtual development environment, incorporating virtual spaces, objects, machinery, devices, subsystems, and actual human action and behavior.

Abstract: A method and system for generating a virtual representation of a physical scene, including receiving scene data corresponding to the physical scene, processing the scene data to determine scene components and scene priors corresponding to the scene components, generating, by a plurality of neural networks, dense geometric representations based at least in part on the scene priors, where each dense geometric representation corresponds to a scene component in the scene components, generating a virtual model of the physical scene based at least in part on the dense geometric representations, and generating a virtual representation of the physical scene based at least in part on the scene data, the virtual representation being aligned with the virtual model.

Abstract: The disclosed computer-implemented method may include acquiring, from a client device within a real-world environment, information representative of the real-world environment, and transmitting the information representative of the real-world environment to a relocalization service. The method may further include receiving, from the relocalization service, (1) an anchor point that may include a mapped position within the real-world environment, and (2) a determined position within the real-world environment of a client device relative to the mapped position of the anchor point. The method may further include sending an identifier of the anchor point to an asset management service, and obtaining, from the asset management service, a digital asset. The method may further include presenting the digital asset at a position within an artificial environment relative to the mapped position of the anchor point. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: A method and system for generating a virtual representation of a physical scene, including receiving scene data corresponding to the physical scene, processing the scene data to determine scene components and scene priors corresponding to the scene components, generating, by a plurality of neural networks, dense geometric representations based at least in part on the scene priors, where each dense geometric representation corresponds to a scene component in the scene components, generating a virtual model of the physical scene based at least in part on the dense geometric representations, and generating a virtual representation of the physical scene based at least in part on the scene data, the virtual representation being aligned with the virtual model.

Abstract: The disclosed computer-implemented method may include acquiring, from a client device within a real-world environment, information representative of the real-world environment, and transmitting the information representative of the real-world environment to a relocalization service. The method may further include receiving, from the relocalization service, (1) an anchor point that may include a mapped position within the real-world environment, and (2) a determined position within the real-world environment of a client device relative to the mapped position of the anchor point. The method may further include sending an identifier of the anchor point to an asset management service, and obtaining, from the asset management service, a digital asset. The method may further include presenting the digital asset at a position within an artificial environment relative to the mapped position of the anchor point. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: The present invention provides methods of screening for and diagnosing prostate cancer and methods of choosing a therapeutic for prostate cancer based on using KDM5D expression level to identify which patients with hormone sensitive prostate cancer benefit from primary castration and taxane and who with castration resistant prostate cancer would benefit from docetaxel plus an androgen receptor antagonists added to the ongoing castration. The disclosure also provides methods of screening for and diagnosing prostate cancer and methods of choosing a therapeutic for prostate cancer based on a lower KDM5D expression having a more aggressive clinical course of prostate cancer in human patients.

Abstract: A method and system for generating a virtual representation of a physical scene, including receiving scene data corresponding to the physical scene, processing the scene data to determine scene components and scene priors corresponding to the scene components, generating, by a plurality of neural networks, dense geometric representations based at least in part on the scene priors, where each dense geometric representation corresponds to a scene component in the scene components, generating a virtual model of the physical scene based at least in part on the dense geometric representations, and generating a virtual representation of the physical scene based at least in part on the scene data, the virtual representation being aligned with the virtual model.

Abstract: A portable sanitizing container; the portable sanitizing container includes a container having a body, a lid having an aperture, a rubber flap covering the aperture and having a series of slits, and an inner volume housing an elongated sponge impregnated with a liquid disinfectant. The elongated sponge is configured to disperse the liquid disinfectant along an outer surface of an item to substantially disinfect an outer surface of the item. The container is configured to receive an item such as a handheld utensil through the aperture, the rubber flap, and the elongated sponge respectively and sanitize the item as the at least one item is inserted and removed from the container. The portable sanitizing container may be beneficial for use by a user to eliminate pathogens, germs and harmful bacteria on shared utensils.

Abstract: A method for determining a visual scene virtual representation and a highly accurate visual scene-aligned geometric representation for virtual interaction.

Abstract: The disclosed computer-implemented method may include acquiring, from a client device within a real-world environment, information representative of the real-world environment, and transmitting the information representative of the real-world environment to a relocalization service. The method may further include receiving, from the relocalization service, (1) an anchor point that may include a mapped position within the real-world environment, and (2) a determined position within the real-world environment of a client device relative to the mapped position of the anchor point. The method may further include sending an identifier of the anchor point to an asset management service, and obtaining, from the asset management service, a digital asset. The method may further include presenting the digital asset at a position within an artificial environment relative to the mapped position of the anchor point. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: The present invention provides methods of screening for and diagnosing prostate cancer and methods of choosing a therapeutic for prostate cancer based on using KDM5D expression level to identify which patients with hormone sensitive prostate cancer benefit from primary castration and taxane and who with castration resistant prostate cancer would benefit from docetaxel plus an androgen receptor antagonists added to the ongoing castration. The disclosure also provides methods of screening for and diagnosing prostate cancer and methods of choosing a therapeutic for prostate cancer based on a lower KDM5D expression having a more aggressive clinical course of prostate cancer in human patients.

Abstract: A method for determining a visual scene virtual representation and a highly accurate visual scene-aligned geometric representation for virtual interaction.

Abstract: The disclosed computer-implemented method may include acquiring, from a client device within a real-world environment, information representative of the real-world environment, and transmitting the information representative of the real-world environment to a relocalization service. The method may further include receiving, from the relocalization service, (1) an anchor point that may include a mapped position within the real-world environment, and (2) a determined position within the real-world environment of a client device relative to the mapped position of the anchor point. The method may further include sending an identifier of the anchor point to an asset management service, and obtaining, from the asset management service, a digital asset. The method may further include presenting the digital asset at a position within an artificial environment relative to the mapped position of the anchor point. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: The present invention provides methods for screening and diagnosing prostate cancer based on a correlation between cancer cell growth, cancer lethality or recurrence and the expression level of ZFP36 or NEDD9 and PTEN in conjunction with ZFP36. The disclosure also provides methods for screening and diagnosing prostate cancer based on a correlation between cancer lethality and the genotype of rs1910301 SNP. Also provided are methods for treating prostate cancer comprising providing a treatment or monitoring based on the expression level of ZFP36, the expression level of NEDD9, and the expression level of ZFP36 in conjunction with PTEN levels or the genotype of rs1910301 SNP.

Abstract: The present invention provides methods of screening for and diagnosing prostate cancer and methods of choosing a therapeutic for prostate cancer based on using KDM5D expression level to identify which patients with hormone sensitive prostate cancer benefit from primary castration and taxane and who with castration resistant prostate cancer would benefit from docetaxel plus an androgen receptor antagonists added to the ongoing castration. The disclosure also provides methods of screening for and diagnosing prostate cancer and methods of choosing a therapeutic for prostate cancer based on a lower KDM5D expression having a more aggressive clinical course of prostate cancer in human patients.