Abstract: A power distribution device includes an input, an output, a power switch controller, and a voltage isolation device. The power distribution device includes, and is designed to provide power to, for example, non-radiation-tolerant or non-radiation hardened components for use in low Earth orbit (LEO) missions. The input is configured to receive power from a power source. The output is configured to provide the power to an electrical load. The power switch controller is configured to selectively operate the power distribution device in a first mode responsive to a first event, and to selectively operate the power distribution device in a second mode responsive to a second event. The voltage isolation device includes a plurality of switches configured, in the first mode, to pass the power between the input and the output, and, in the second mode, to interrupt the passage of the power between the input and the output.