Abstract: The present invention relates to an isolated antibody or antigen-binding fragment thereof that binds to human A2AP. The isolated antibody or antigen-binding fragment according to the present invention i) cross-reacts with rabbit and/or cynomolgus A2AP, ii) does not inhibit human plasmin activity, and iii) increases plasmin mediated clot lysis in the presence of A2AP.

Abstract: Nitrogen containing compounds may have formulas (I), (II) and (IV), and such compounds may be suitable for detecting alkyne group containing organic compounds by mass spectrometry. Furthermore, methods may also include synthesizing these compounds, detecting of organic compounds containing the specific compounds, uses of the compounds in mass spectrometry for determining enzyme activity or monitoring the lipid metabolism in a cell, and a kit which contains at least one of these compounds and at least one internal standard.

Abstract: The present invention relates to an isolated antibody or antigen-binding fragment thereof that binds to human A2AP. The isolated antibody or antigen-binding fragment according to the present invention i) cross-reacts with rabbit and/or cynomolgus A2AP, ii) does not inhibit human plasmin activity, and iii) increases plasmin mediated clot lysis in the presence of A2AP.

Abstract: The present invention relates to an isolated antibody or antigen-binding fragment thereof that binds to human A2AP. The isolated antibody or antigen-binding fragment according to the present invention i) cross-reacts with rabbit and/or cynomolgus A2AP, ii) does not inhibit human plasmin activity, and iii) increases plasmin mediated clot lysis in the presence of A2AP.

Abstract: The present invention relates to an isolated antibody or antigen-binding fragment thereof that binds to human A2AP. The isolated antibody or antigen-binding fragment according to the present invention i) cross-reacts with rabbit and/or cynomolgus A2AP, ii) does not inhibit human plasmin activity, and iii) increases plasmin mediated clot lysis in the presence of A2AP.

Abstract: The present disclosure provides a computer implemented method for facilitating a teaching surgeon to teach or assist a learning surgeon in minimally invasive interventions using a surgical instrument including displaying endoscopic images of an intervention site in real time on a display device, said endoscopic images being captured using a camera associated with an endoscopic instrument, and tracking a movement of one or both hands of said teaching surgeon and/or a device held by said teaching surgeon, using a real-time tracking apparatus, wherein said real-time tracking apparatus comprises a tracking system and a computing device, wherein said tracking of said movement comprises recording a sequence of tracking information of one or both hands of said teaching surgeon and/or the device held by said teaching surgeon.

Abstract: A planter apparatus is disclosed herein. The planter apparatus includes a growth chamber; a transmissivity-reducing window adjustable from a substantially opaque state to a substantially transparent state. The window can include a first transmissivity-reducing layer and a second transmissivity-reducing layer coupled to the first transmissivity-reducing layer, and at least a portion of the growth chamber is viewable through the window when the window is in the substantially transparent state. The planter apparatus includes a transmissivity controller for operating the window between the substantially opaque state and the substantially transparent state. For example, the first transmissivity-reducing layer can include a switching film and the second transmissivity-reducing layer can include a gel filter.

Abstract: An orthosis and a method for the production thereof are provided. The orthosis includes a first support section and at least one further support section that form a three-dimensional support body. The support sections rest on the patient and support limbs or body areas of the patient. The orthosis also comprises fixing means which engage on the support body and which fix the orthosis on the patient. The support body comprising the support sections includes a reinforcing structure that comprises a support layer onto which at least one reinforcing thread is sewn. A pattern layout of the reinforcing thread is oriented along force lines corresponding to stresses that occur in the support body. The layout of the reinforcing thread lies within a surface on the support layer, said surface corresponding to a two-dimensional pattern layout of the three-dimensional support body.

Abstract: A domestic appliance includes a door configured to pivot about a horizontal axis of rotation so as to assume a substantially vertical position when closed to thereby close a treatment chamber. The axis of rotation is arranged behind a center of gravity of the door in a depthwise direction of the domestic appliance. When closed, the door is locked by a locking arrangement. A door weight compensation system damps an opening movement and/or assists a closing movement of the door and is configured to enable the door in an unlocked state to assume a partially open position, in which the door is open to some degree, substantially as a result of a weight-induced force exerted by the door.

Abstract: Various embodiments of systems and methods for inventory verification using inventory snapshots are described herein. In response to a first inventory posting in a current time period, a current open inventory snapshot is created with inventory information. If there is a previously open inventory snapshot that is created in a previous time period before the current period, then the previously open inventory snapshot is closed. To verify inventory for a past time period, a difference between an inventory snapshot that is valid for the past time period and an inventory snapshot that is valid for a time period previous to the past time period is compared with aggregated inventory change confirmations posted in the past time period. An error indicator is provided if there is a mismatch between the difference and the aggregated inventory change confirmations.

Abstract: A business object model, which reflects data that is used during a given business transaction, is utilized to generate interfaces. This business object model facilitates commercial transactions by providing consistent interfaces that are suitable for use across industries, across businesses, and across different departments within a business during a business transaction. In some operations, software creates, updates, or otherwise processes information related to a production confirmation business object.

Abstract: A business object model, which reflects data that is used during a given business transaction, is utilized to generate interfaces. This business object model facilitates commercial transactions by providing consistent interfaces that are suitable for use across industries, across businesses, and across different departments within a business during a business transaction. In some operations, software creates, updates, or otherwise processes information related to a site logistics confirmation and a site logistics request business object.

Abstract: A business object model, which reflects data that is used during a given business transaction, is utilized to generate interfaces. This business object model facilitates commercial transactions by providing consistent interfaces that are suitable for use across industries, across businesses, and across different departments within a business during a business transaction. In some operations, software creates, updates, or otherwise processes information related to a goods and activity confirmation business object.

Abstract: A business object model, which reflects data that is used during a given business transaction, is utilized to generate interfaces. This business object model facilitates commercial transactions by providing consistent interfaces that are suitable for use across industries, across businesses, and across different departments within a business during a business transaction. In some operations, software creates, updates, or otherwise processes information related to a cost object settlement rule and an inventory notification business object.

Abstract: A business object model, which reflects data that is used during a given business transaction, is utilized to generate interfaces. This business object model facilitates commercial transactions by providing consistent interfaces that are suitable for use across industries, across businesses, and across different departments within a business during a business transaction. In some operations, software creates, updates, or otherwise processes information related to a goods and activity confirmation business object.

Abstract: A business object model, which reflects data that is used during a given business transaction, is utilized to generate interfaces. This business object model facilitates commercial transactions by providing consistent interfaces that are suitable for use across industries, across businesses, and across different departments within a business during a business transaction. In some operations, software creates, updates, or otherwise processes information related to a point of sale transaction business object.

Abstract: Systems, methods, computer program products, and the like for testing to validate software operations are described. A first part of a test can be executed in a tenant currently having a first system state. The tenant can be transitioned from the first system state to a second system state. The transitioning can have an unknown effect on a business process or business scenario running in the tenant. A second part of the test can be executed in the tenant while the tenant is in the second system state. Upon completion of the test, it can be determined whether the transition of the tenant from the first system state to the second system state negatively impacts the running of the business process or business scenario.

Abstract: An orthosis and a method for the production thereof are provided. The orthosis includes a first support section and at least one further support section that form a three-dimensional support body. The support sections rest on the patient and support limbs or body areas of the patient. The orthosis also comprises fixing means which engage on the support body and which fix the orthosis on the patient. The support body comprising the support sections includes a reinforcing structure that comprises a support layer onto which at least one reinforcing thread is sewn. A pattern layout of the reinforcing thread is oriented along force lines corresponding to stresses that occur in the support body. The layout of the reinforcing thread lies within a surface on the support layer, said surface corresponding to a two-dimensional pattern layout of the three-dimensional support body.

Abstract: A business object model, which reflects data that is used during a given business transaction, is utilized to generate interfaces. This business object model facilitates commercial transactions by providing consistent interfaces that are suitable for use across industries, across businesses, and across different departments within a business during a business transaction. In some operations, software creates, updates, or otherwise processes information related to a point of sale transaction business object.

Abstract: Various embodiments of systems and methods for inventory verification using inventory snapshots are described herein. In response to a first inventory posting in a current time period, a current open inventory snapshot is created with inventory information. If there is a previously open inventory snapshot that is created in a previous time period before the current period, then the previously open inventory snapshot is closed. To verify inventory for a past time period, a difference between an inventory snapshot that is valid for the past time period and an inventory snapshot that is valid for a time period previous to the past time period is compared with aggregated inventory change confirmations posted in the past time period. An error indicator is provided if there is a mismatch between the difference and the aggregated inventory change confirmations.