Abstract: An implant includes a hollow biocompatible shell, first and second electrodes, filling material, and circuitry. The hollow biocompatible shell is configured to be implanted in an organ of a patient. The first electrode is disposed inside the shell. The second electrode has at least one surface disposed outside the shell. The filling material, which includes carbon nanotubes (CNT), fills the shell and is configured, in response to a rupture occurring in the shell, to change a spatial orientation of the CNT and thus to cause a change in electrical conductivity of the filling material between the first electrode and the rupture. The circuitry is electrically connected to the first and second electrodes and is configured to detect the rupture by sensing the change in the electrical conductivity of the CNT, and to produce an output indicative of the detected rupture.

Abstract: Cardiac catheterization is conducted using a probe having a balloon assembly, in which a spring has a resting axially elongated configuration and a torsed, axially shortened configuration. An inflatable balloon is twisted about the spring and mechanically linked to the spring. A flexible sheath is disposed about the spring within the balloon, the sheath and the wall of the balloon defining a chamber to contain a fluid flowing therein and thereout for inflation of the balloon and deflation of the balloon so as to energize and de-energize the spring.

Abstract: A system for assessing occlusion of a region to blood flow includes a catheter with an inflatable member, a first electrode configured for placement upstream of the inflatable member and the second electrodes configured for placement downstream of the inflatable member, the inflatable member configured for inflation to occlude the blood flow through the region. The system further includes a current/voltage source, a resistor and a voltmeter, wherein these components along with the first and second electrodes are configured to form an impedance measuring circuit configured to detect a change in impedance for indicating occlusion of the region to the blood flow.

Abstract: A method of constructing an inflatable electrode assembly configured for irrigation, comprises: providing a flex circuit having a substrate with a pre-formed aperture, the substrate constructed of a material having a greater heat resistance or a first melting temperature; providing a balloon member with a membrane, the membrane constructed of a material having a lesser heat resistance or a second melting temperature lower than the first melting temperature of the substrate; affixing the substrate to the membrane wherein a surrounding portion of the substrate around the pre-formed aperture masks a surrounding portion of the membrane so as to expose a target portion of the membrane; and applying heat to the target portion of the membrane through the pre-formed aperture of the substrate, wherein the heat applied, without melting the substrate, melts the target portion of the membrane in forming an aperture in the membrane.

Abstract: An irrigated balloon catheter for use in an ostium of a pulmonary vein, includes a flex circuit electrode assembly adapted for circumferential contact with the ostium when the balloon is inflated. Adapted for both diagnostic and therapeutic applications and procedures, the balloon catheter may be used with a lasso catheter or focal catheter. The flex circuit electrode assembly includes a substrate, a contact electrode on an outer surface of the substrate, the contact electrode having a “fishbone” configuration with a longitudinally elongated portion and a plurality of transversal fingers, and a wiring electrode on an inner surface of the substrate, and conductive vias extending through the substrate electrically coupling the contact electrode and the writing electrodes. Microelectrodes with exclusion zones are strategically positioned relative to the electrodes. The electrodes may also be split into electrode portions.

Abstract: A method of constructing an electrophysiology catheter having a flex circuit electrode assembly includes: providing a flex circuit having a substrate, a first conductive layer and a second conductive layer; removing the first conductive layer to expose a first surface of the substrate; forming the wiring electrode in the second conductive layer with one exclusion zone; forming a first through-hole in the substrate to provide one conductive via and forming a second through-hole to provide an irrigation aperture in alignment with the exclusion zone; forming the contact electrode on first surface of the substrate; placing conductive material into the first through-hole to form the conductive via, the conductive via extending through the substrate and electrically coupling the wiring electrode and the contact electrode; and coupling a first conductor and a second conductor to the wiring electrode to form a thermocouple.

Abstract: A catheter adapted for greater mapping resolution and location precision has a basket-shaped, high density electrode assembly for large-area mapping, and an integrated distal tip providing an array of ultra-high density microelectrodes for acute focal mapping. The basket-shaped electrode assembly 18 has a plurality of electrode-carrying spines and the distal tip has a nonmetallic, electrically insulating substrate body with indentations in which microelectrodes are positioned in a manner that the outer surface is generally flush with the outer surface of the substrate body to present a generally smooth, atraumatic distal tip profile.

Abstract: A cable connector, including a housing having a base and a lip, which surrounds the base and defines an aperture configured to receive a mating plug. The cable connector also includes a plurality of electrical contacts enclosed by the housing and configured to convey electrical signals, the electrical contacts having respective first proximal and first distal ends, the first proximal ends being implanted in the base so that the first distal ends are recessed within the aperture at a first distance from the base. The cable connector additionally includes one or more optical fiber terminals containing end portions of respective optical fibers configured to convey optical signals and having respective second proximal and second distal ends, the second proximal ends being implanted in the base so that the second distal ends are recessed within the aperture at a second distance from the base, which is greater than the first distance.

Abstract: A method, including incorporating a conducting wire into a tubular braid consisting of a multiplicity of supporting wires, and covering the tubular braid with a sheath. The method further includes identifying a location of the conducting wire within the tubular braid and attaching an electrode through the sheath to the conducting wire at the location.

Abstract: A catheter probe comprises an insertion tube, and a distal end with a distal electrode, a force sensor to detect force on the distal electrode, and an irrigated electrode mounted on a coupling member of the force sensor, which has a tubular form surrounding a central space occupied by components, including force sensing coils. A fluid diverter that passes fluid to the proximal irrigated electrode is configured as an insert or an integrated projection of the coupling member, which configuration minimizes its space demand within the coupling member. Thus, the diameter of the distal end need not be increased. The fluid diverter has a proximal entry opening and a distal exit opening connected by a fluid passage with at least a radial branch and at least an axial branch. The irrigated electrode is mounted over the distal exit opening to receive fluid from the fluid passage.

Abstract: A catheter adapted for greater mapping resolution and location precision has a basket-shaped, high density electrode assembly for large-area mapping, and an integrated distal tip providing an array of ultra-high density microelectrodes for acute focal mapping. The basket-shaped electrode assembly 18 has a plurality of electrode-carrying spines and the distal tip has a nonmetallic, electrically insulating substrate body with indentations in which microelectrodes are positioned in a manner that the outer surface is generally flush with the outer surface of the substrate body to present a generally smooth, atraumatic distal tip profile.

Abstract: An implantable device includes a hollow biocompatible shell and filling material. The shell is configured to be implanted in an organ of a patient. The filling material is configured to fill the shell so as to assume a specified shape of the implantable device, and is visually distinguished from tissue of the organ that surrounds the implantable device.

Abstract: Tissue ablation is carried out using a probe having a distal conductive cap. At least one optical fiber is contained within the probe and terminates in proximity to an outer surface of the conductive cap. The optical fiber conveys optical radiation to the tissue while the power generator is activated and receives reflected optical radiation. An optical module measures the received reflected optical radiation, and a processor linked to the optical module analyzes the reflected optical radiation to determine impending steam pop events.

Abstract: Ablation apparatus is provided. The apparatus includes an ablation electrode shaped to define a cavity thereof, and comprising a metallic distal face that is shaped to define a plurality of apertures. A fluid-delivery channel is configured to deliver fluid to the apertures. At least one ultrasound transducer is disposed within the cavity of the ablation electrode, the transducer being configured to transmit an ultrasound wave through the apertures. Other embodiments are also described.

Abstract: A method, consisting of providing a metal wire having a wire diameter and an end, and positioning a conductor at a distance from the end of the wire. The method further includes creating an electrical discharge between the conductor and the end, while setting the distance and an electrical potential of the discharge, so as to create a bead of a predefined size on the end. The method also includes assembling the wire with the created bead into an invasive probe, so that the bead is positioned at an outer surface of the probe.

Abstract: A probe, including an insertion tube and an electrode mounted on a distal end of the insertion tube. A force sensor is mounted in the distal end of the insertion tube. The force sensor has a central opening and is configured to measure a force on the distal end. The probe also includes tubing, passing through the central opening, which is configured to supply irrigation fluid through apertures in the electrode.

Abstract: A catheter having a catheter shaft that has a more uniform construction throughout its length and is able to provide more than one deflection curvature. The catheter shaft includes a flexible outer tubular member, and a less flexible inner tubular member extending through the outer tubular member in a proximal section of the catheter shaft, wherein the inner tubular member is afforded longitudinal movement relative to the outer tubular member. The catheter also includes at least one puller wire extending through the inner tubular member to deflect a distal deflection section of the catheter shaft, wherein longitudinal movement of the inner tubular member relative to the outer tubular member enables an operator to select and set a deflection curvature of the distal deflection section.

Abstract: An improved thermocouple includes a drawn coaxial thermocouple wire pair having a more precise “hot” junction at which a first and second metallic material electrically connect with each other for measuring temperature. Adapted for use with an electrophysiologic catheter, the improved thermocouple comprising an elongated body having a proximal end and a distal end. The body includes a core of a first metallic material, a first coaxial layer of ceramic material, and a second coaxial layer of a second metallic material. The thermocouple further includes a solder cap on the distal end, the solder cap electrically connecting the core and the second layer at the distal end. A method of manufacturing includes drawing the body through a die, and applying solder on a distal end of the body to electrically connect the two metallic materials at the distal end.

Abstract: Cardiac catheterization is conducted using a probe having a balloon assembly, in which a spring has a resting axially elongated configuration and a torsed, axially shortened configuration. An inflatable balloon is twisted about the spring and mechanically linked to the spring. A flexible sheath is disposed about the spring within the balloon, the sheath and the wall of the balloon defining a chamber to contain a fluid flowing therein and thereout for inflation of the balloon and deflation of the balloon so as to energize and de-energize the spring.

Abstract: A probe includes an insertion tube, a magnetic field sensor, a dummy load mounted adjacent to the magnetic field sensor, and a braid. The braid includes multiple braid wires that traverse a length of the insertion tube. A first pair of the braid wires is connected across the magnetic field sensor, and a second pair of the braid wires is connected across the dummy load.