Patents by Inventor Christopher Todd Hittinger

Christopher Todd Hittinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11913016
    Abstract: Methods of making synthetic yeast cells by mating together two diploid (or higher ploidy) yeast species or hybrids to generate multi-ploid yeast hybrids are provided herein. The synthetic yeast cells made by this process and kits for performing the process are also provided.
    Type: Grant
    Filed: November 7, 2017
    Date of Patent: February 27, 2024
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: William Gerald Alexander, David Peris Navarro, Christopher Todd Hittinger
  • Patent number: 10870858
    Abstract: Provided herein are constructs for genome editing or genetic engineering its fungi or protists, methods of using the constructs and media for use in selecting cells. The construct include a polynucleotide encoding a thymidine kinase operably connected to a promoter, suitably a constitutive promoter; a polynucleotide encoding an endonuclease operably connected to an inducible promoter; and a recognition site for the endonuclease. The constructs may also include selectable markers for use in selecting recombinations.
    Type: Grant
    Filed: January 24, 2018
    Date of Patent: December 22, 2020
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Christopher Todd Hittinger, William Gerald Alexander
  • Publication number: 20180155732
    Abstract: Provided herein are constructs for genome editing or genetic engineering its fungi or protists, methods of using the constructs and media for use in selecting cells. The construct include a polynucleotide encoding a thymidine kinase operably connected to a promoter, suitably a constitutive promoter; a polynucleotide encoding an endonuclease operably connected to an inducible promoter; and a recognition site for the endonuclease. The constructs may also include selectable markers for use in selecting recombinations.
    Type: Application
    Filed: January 24, 2018
    Publication date: June 7, 2018
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Christopher Todd Hittinger, William Gerald Alexander
  • Publication number: 20180127784
    Abstract: Methods of making synthetic yeast cells by mating together two diploid (or higher ploidy) yeast species or hybrids to generate multi-ploid yeast hybrids are provided herein. The synthetic yeast cells made by this process and kits for performing the process are also provided.
    Type: Application
    Filed: November 7, 2017
    Publication date: May 10, 2018
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: William Gerald ALEXANDER, David Peris NAVARRO, Christopher Todd HITTINGER
  • Patent number: 9879270
    Abstract: Provided herein are constructs for genome editing or genetic engineering in fungi or protists, methods of using the constructs and media for use in selecting cells. The construct include a polynucleotide encoding a thymidine kinase operably connected to a promoter, suitably a constitutive promoter; a polynucleotide encoding an endonuclease operably connected to an inducible promoter; and a recognition site for the endonuclease. The constructs may also include selectable markers for use in selecting recombinations.
    Type: Grant
    Filed: August 14, 2015
    Date of Patent: January 30, 2018
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Christopher Todd Hittinger, William Gerald Alexander
  • Publication number: 20160046952
    Abstract: Provided herein are constructs for genome editing or genetic engineering in fungi or protists, methods of using the constructs and media for use in selecting cells. The construct include a polynucleotide encoding a thymidine kinase operably connected to a promoter, suitably a constitutive promoter; a polynucleotide encoding an endonuclease operably connected to an inducible promoter; and a recognition site for the endonuclease. The constructs may also include selectable markers for use in selecting recombinations.
    Type: Application
    Filed: August 14, 2015
    Publication date: February 18, 2016
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Christopher Todd Hittinger, William Gerald Alexander