Abstract: A device and method for removing closures from laboratory sample containers is the subject of the present invention. The device consists of a tubular member which is large enough to contain a laboratory sample container or vial. Integral with one end of the tubular member is a housing member which is large enough to contain the stopper or closure for the laboratory vial and is thus of a diameter larger than the tubular member. The end of the housing opposite the tubular member is closable with an irreversibly locking cap. A vial with a stopper to be removed is placed into the cap end of the housing member and is received by the tubular member unitl the stopper rests on the bottom surface of the housing member. The cap on the housing member is closed and a force is exerted on the vial to dislodge the stopper from it. The vial is pulled through the tubular member, leaving the stopper in the housing member.