Abstract: Disclosed herein is a device comprising: a media configured to convert nitrogen dioxide into nitric oxide, wherein the media comprises: (a) a support material; and (b) an antioxidant material, wherein at least 15 wt % of the antioxidant material is present in a solid form.

Abstract: Disclosed herein is a system and method comprising an apparatus for delivering a therapeutic amount of nitric oxide to a subject, the apparatus comprising at least one air inlet; a first receptacle configured to host a first source of nitric oxide; a second receptacle configured to host a second source of nitric oxide; a control unit configured to communicate with the first receptacle and the second receptacle and to selectively couple the at least one air inlet to at least one of the first receptacle or the second receptacle to deliver the nitric oxide from the first or the second source; a first outlet coupled to the first receptacle to deliver nitric oxide; and a second outlet coupled to the second receptacle to deliver nitric oxide. The first source can be provided to a ventilator and the second source can be provided to an ECMO device.

Abstract: Disclosed herein is a single-use container for forming a therapeutic amount of nitric oxide to be delivered by an apparatus to a subject, wherein the single-use container comprises: a housing defined by a proximal edge and a distal edge and comprising: a first chamber comprising N2O4, wherein the first chamber is sealed; a second chamber comprising an antioxidant material; and wherein the first chamber and the second chamber are positioned relative to each other such that when the single-use container is inserted into the apparatus and is activated, the first chamber is unsealed to allow the liquid N2O4 to be in fluid communication with the antioxidant material in the second chamber to produce nitric oxide.

Abstract: Disclosed herein is a device comprising: a media configured to convert nitrogen dioxide into nitric oxide, wherein the media comprises: (a) a support material having a surface area of 350 to 5000 m2/g; and (b) an antioxidant material.

Abstract: Airway adapters, suction catheter systems, and methods of using the same are described herein. An exemplary airway adapter assembly may comprise a connector body portion having a first end and a second end, an elongate cavity having an axial center can be defined between the first and the second end, and a valve can be coupled to the second end of the connector body. The exemplary airway adapter assembly may also comprise a ventilation base member comprising a tubular portion coupled to the second end of the connector body portion and ventilator port. The ventilator port may comprises a conduit having a first conduit end and a second conduit end, and the first conduit end may be coupled to the tubular portion through an articulable connection. An exemplary closed suction catheter system may comprise a suction control valve assembly and a closed suction catheter sheath.

Abstract: A gas elimination apparatus and a method for use in an intravenous delivery system are provided. The apparatus includes a fluid inlet coupling a fluid flow into a liquid chamber, a fluid outlet protruding into the liquid chamber, and a flow diversion member proximal to the fluid outlet. The flow diversion member configured to block a direct flow between the fluid inlet and the fluid outlet. The apparatus includes a membrane separating a portion of the liquid chamber from an outer chamber and a gas venting valve fluidically coupling the outer chamber with the atmosphere. The flow diversion member may be mechanically supported by at least one strut or elongate member extending along a flow direction into the liquid chamber.

Abstract: A gas elimination apparatus and a method for use in an intravenous delivery system are provided. The apparatus includes a fluid inlet coupling a fluid flow into a liquid chamber, a fluid outlet protruding into the liquid chamber, and a flow diversion member proximal to the fluid outlet. The flow diversion member configured to block a direct flow between the fluid inlet and the fluid outlet. The apparatus includes a membrane separating a portion of the liquid chamber from an outer chamber and a gas venting valve fluidically coupling the outer chamber with the atmosphere. The flow diversion member may be mechanically supported by at least one strut or elongate member extending along a flow direction into the liquid chamber.

Abstract: A gas elimination apparatus and a method for use in an intravenous delivery system are provided. The apparatus includes in a fluid inlet coupling a fluid flow into a liquid chamber, a fluid outlet protruding into the liquid chamber, and a flow diversion member proximal to the fluid outlet. The flow diversion member configured to block a direct flow between the fluid inlet and the fluid outlet. The apparatus includes a membrane separating a portion of the liquid chamber from an outer chamber and a gas venting valve fluidically coupling the outer chamber with the atmosphere. The flow diversion member may be mechanically supported by at least one strut or elongate member extending along a flow direction into the liquid chamber.

Abstract: A resuscitator has a patient airway interface device, a bag, a fluid passage coupled between the bag and patient airway interface device, and a sensor module. The patient airway interface device may be a mask or an endotracheal tube. The sensor module can have a display, at least one sensor coupled to the flow passage and configured to provide a measurement of at least one parameter, and a processor coupled to the display and the at least one sensor. The processor is configured to receive the measurement from the sensor and provide information on the display based on the received measurement. The information may include a current breath rate, a pressure-vs-time curve, and guidance to the user to assist in achieving a target breath rate.

Abstract: A fluid warming device has a heat exchange body having an input port and an output port and conducts fluid from the input port to the output port. The fluid warming device has a heater assembly configured to transfer heat to the heat exchange body. The fluid warming device may also have a temperature sensor for measuring a temperature of the heater assembly, and a power sensor for measuring a power to the heater assembly. The fluid warming device also has a controller connected to the temperature sensor and the power sensor. The controller calculates a fluid flow rate and a total volume of fluid delivered through the heat exchange body based on the temperature and the power.

Abstract: A gas elimination apparatus and a method for use in an intravenous delivery system are provided. The apparatus includes a fluid inlet coupling a fluid flow into a liquid chamber, a fluid outlet protruding into the liquid chamber, and a flow diversion member proximal to the fluid outlet. The flow diversion member configured to block a direct flow between the fluid inlet and the fluid outlet. The apparatus includes a membrane separating a portion of the liquid chamber from an outer chamber and a gas venting valve fluidically coupling the outer chamber with the atmosphere. The flow diversion member may be mechanically supported by at least one strut or elongate member extending along a flow direction into the liquid chamber.

Abstract: A gas elimination apparatus and a method for use in an intravenous delivery system are provided. The apparatus includes in a fluid inlet coupling a fluid flow into a liquid chamber, a fluid outlet protruding into the liquid chamber, and a flow diversion member proximal to the fluid outlet. The flow diversion member configured to block a direct flow between the fluid inlet and the fluid outlet. The apparatus includes a membrane separating a portion of the liquid chamber from an outer chamber and a gas venting valve fluidically coupling the outer chamber with the atmosphere. The flow diversion member may be mechanically supported by at least one strut or elongate member extending along a flow direction into the liquid chamber.

Abstract: A gas elimination apparatus and a method for use in an intravenous delivery system are provided. The apparatus includes a fluid inlet coupling a fluid flow into a liquid chamber, a fluid outlet protruding into the liquid chamber, and a flow diversion member proximal to the fluid outlet. The flow diversion member configured to block a direct flow between the fluid inlet and the fluid outlet. The apparatus includes a membrane separating a portion of the liquid chamber from an outer chamber and a gas venting valve fluidically coupling the outer chamber with the atmosphere. The flow diversion member may be mechanically supported by at least one strut or elongate member extending along a flow direction into the liquid chamber.

Abstract: A nonwoven wipe comprises an antiseptic solution comprising a bis-(dihydropyridinyl)-decane derivative, a first fiber having a denier of about 1.5 to about 2.0, and a second fiber having a denier of about 3.0 to 3.5. About 30 wt % to 70 wt % of the total weight of the nonwoven wipe is the first fiber and about 30 wt % to 70 wt % of the total weight of the nonwoven wipe is the second fiber. The bis-(dihydropyridinyl)-decane may be octenidine dihydrochloride.

Abstract: Airway adapters and suction catheter systems, and methods of using the same, are described herein. An exemplary airway adapter assembly may comprise a connector body portion having a first end and a second end. The connector body portion may define an elongate cavity having an axial center between the first and the second end. The exemplary airway adapter assembly may also comprise a valve coupled to the second end of the connector body. The exemplary airway adapter assembly may also comprise a ventilation base member comprising a tubular portion coupled to the second end of the connector body portion and ventilator port. The ventilator port may comprises a conduit having a first conduit end and a second conduit end, and the first conduit end may be coupled to the tubular portion through an articulable connection. An exemplary closed suction catheter system may comprise a suction control valve assembly and a closed suction catheter sheath.

Abstract: Airway adapters and suction catheter systems, and methods of using the same, are described herein. An exemplary airway adapter assembly may comprise a connector body portion having a first end and a second end. The connector body portion may define an elongate cavity having an axial center between the first and the second end. The exemplary airway adapter assembly may also comprise a valve coupled to the second end of the connector body. The exemplary airway adapter assembly may also comprise a ventilation base member comprising a tubular portion coupled to the second end of the connector body portion and ventilator port. The ventilator port may comprises a conduit having a first conduit end and a second conduit end, and the first conduit end may be coupled to the tubular portion through an articulable connection. An exemplary closed suction catheter system may comprise a suction control valve assembly and a closed suction catheter sheath.

Abstract: A gas elimination apparatus and a method for use in an intravenous delivery system are provided. The apparatus includes a fluid inlet coupling a fluid flow into a liquid chamber, a fluid outlet protruding into the liquid chamber, and a flow diversion member proximal to the fluid outlet. The flow diversion member configured to block a direct flow between the fluid inlet and the fluid outlet. The apparatus includes a membrane separating a portion of the liquid chamber from an outer chamber and a gas venting valve fluidically coupling the outer chamber with the atmosphere. The flow diversion member may be mechanically supported by at least one strut or elongate member extending along a flow direction into the liquid chamber.

Abstract: A gas elimination apparatus and a method for use in an intravenous delivery system are provided. The apparatus includes a fluid inlet coupling a fluid flow into a liquid chamber, a fluid outlet protruding into the liquid chamber, and a flow diversion member proximal to the fluid outlet. The flow diversion member configured to block a direct flow between the fluid inlet and the fluid outlet. The apparatus includes a membrane separating a portion of the liquid chamber from an outer chamber and a gas venting valve fluidically coupling the outer chamber with the atmosphere. The flow diversion member may be mechanically supported by at least one strut or elongate member extending along a flow direction into the liquid chamber.

Abstract: A method for reducing a loss of medication from a nebulizer includes the steps of entraining a liquid medication into a first flow of a pressurized gas into a nebulizer chamber and also entraining an additional amount of the liquid medication into a second flow of ambient air drawn into the nebulizer chamber through an opening when a patient inhales through the nebulizer chamber. When the patient exhales, a portion of the exhaled breath is directed into the outlet of the nebulizer chamber, thereby increasing a backpressure within the outlet and substantially stopping the second flow of ambient air into the nebulizer chamber, thereby decreasing the amount of medication lost to the ambient environment while the patient is not inhaling.

Abstract: A resuscitator has a patient airway interface device, a bag, a fluid passage coupled between the bag and patient airway interface device, and a sensor module. The patient airway interface device may be a mask or an endotracheal tube. The sensor module can have a display, at least one sensor coupled to the flow passage and configured to provide a measurement of at least one parameter, and a processor coupled to the display and the at least one sensor. The processor is configured to receive the measurement from the sensor and provide information on the display based on the received measurement. The information may include a current breath rate, a pressure-vs-time curve, and guidance to the user to assist in achieving a target breath rate.