Patents by Inventor Christopher W. Cluff

Christopher W. Cluff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and uses
    Patent number: 11207404
    Abstract: The present invention relates to immunogenic compositions and methods for producing them, and in particular, immunogenic compositions comprising a protein antigen cross linked to an oxoadenine adjuvant.
    Type: Grant
    Filed: April 15, 2020
    Date of Patent: December 28, 2021
    Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: David Burkhart, Michael Cochran, Christopher W Cluff, Daniel Larocque, Helene G. Bazin-Lee, Julien St-Jean
  • COMPOSITIONS AND USES
    Publication number: 20200345841
    Abstract: The present invention relates to immunogenic compositions and methods for producing them, and in particular, immunogenic compositions comprising a protein antigen cross linked to an oxoadenine adjuvant.
    Type: Application
    Filed: April 15, 2020
    Publication date: November 5, 2020
    Applicant: GLAXOSMITHKLINE BIOLOGICALS, SA
    Inventors: David BURKHART, Michael COCHRAN, Christopher W. CLUFF, Daniel LAROCQUE, Helene G BAZIN-LEE, Julien ST JEAN
  • TLR4 agonists and compositions thereof and their use in the treatment of cancer
    Patent number: 10765690
    Abstract: Disclosed is a TLR4 agonist alone or in combination with an anti-cancer agent and pharmaceutical compositions thereof, uses thereof, and methods of treatment comprising administering said composition or combination, including uses in cancer.
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: September 8, 2020
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Christopher W. Cluff, Hua-Xin Gao
  • Compositions and uses
    Patent number: 10646566
    Abstract: The present invention relates to immunogenic compositions and methods for producing them, and in particular, immunogenic compositions comprising a protein antigen cross linked to an oxoadenine adjuvant.
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: May 12, 2020
    Assignee: GLAXOSMITHKLINE BIOLOGICALS S.A.
    Inventors: David Burkhart, Michael Cochran, Christopher W Cluff, Daniel Larocque, Helene G Bazin-Lee, Julien St Jean
  • TLR4 agonists and compositions thereof and their use in the treatment of cancer
    Publication number: 20180221399
    Abstract: Disclosed is a TLR4 agonist alone or in combination with an anti-cancer agent and pharmaceutical compositions thereof, uses thereof, and methods of treatment comprising administering said composition or combination, including uses in cancer.
    Type: Application
    Filed: June 3, 2016
    Publication date: August 9, 2018
    Inventors: Christopher W. CLUFF, Hua-Xin GAO
  • COMPOSITIONS AND USES
    Publication number: 20180036403
    Abstract: The present invention relates to immunogenic compositions and methods for producing them, and in particular, immunogenic compositions comprising a protein antigen cross linked to an oxoadenine adjuvant.
    Type: Application
    Filed: March 9, 2016
    Publication date: February 8, 2018
    Applicant: GLAXOSMITHKLINE BIOLOGICALS, SA
    Inventors: David BURKHART, Michael COCHRAN, Christopher W CLUFF, Daniel LAROCQUE, Helene G BAZIN-LEE, Julien ST JEAN
  • Prophylactic and therapeutic treatment of infectious and other diseases with immunoeffector compounds
    Patent number: 7829542
    Abstract: Methods and compositions for treating or ameliorating diseases and other conditions, such as infectious diseases, autoimmune diseases and allergies are provided. The methods employ cyclic AGPs for selectively stimulating immune responses in animals and plants.
    Type: Grant
    Filed: May 30, 2008
    Date of Patent: November 9, 2010
    Assignee: Corixa Corporation
    Inventors: Jory R. Baldridge, David A. Johnson, Christopher W. Cluff
  • PROPHYLACTIC AND THERAPEUTIC TREATMENT OF INFECTIOUS AND OTHER DISEASES WITH IMMUNOEFFECTOR COMPOUNDS
    Publication number: 20080227729
    Abstract: Methods and compositions for treating or ameliorating diseases and other conditions, such as infectious diseases, autoimmune diseases and allergies are provided. The methods employ cyclic AGPs for selectively stimulating immune responses in animals and plants.
    Type: Application
    Filed: May 30, 2008
    Publication date: September 18, 2008
    Applicant: Corixa Corporation
    Inventors: Jory R. Baldridge, David A. Johnson, Christopher W. Cluff
  • Prophylactic and therapeutic treatment of infectious and other diseases with immunoeffector compounds
    Patent number: 6911434
    Abstract: Methods and compositions for treating or ameliorating diseases and other conditions, such as infectious diseases, autoimmune diseases and allergies are provided. The methods employ cyclic AGPs for selectively stimulating immune responses in animals and plants.
    Type: Grant
    Filed: February 4, 2002
    Date of Patent: June 28, 2005
    Assignee: Corixa Corporation
    Inventors: Jory R. Baldridge, David A. Johnson, Christopher W. Cluff
  • Prophylactic and therapeutic treatment of infectious and other diseases with immunoeffector compounds
    Publication number: 20030148993
    Abstract: Methods and compositions for treating or ameliorating diseases and other conditions, such as infectious diseases, autoimmune diseases and allergies are provided. The methods employ cyclic AGPs for selectively stimulating immune responses in animals and plants.
    Type: Application
    Filed: February 4, 2002
    Publication date: August 7, 2003
    Applicant: Corixa Corporation
    Inventors: Jory R. Baldridge, David A. Johnson, Christopher W. Cluff
  • Immunoeffector compounds
    Patent number: 6525028
    Abstract: This invention provides compounds containing a 2-deoxy-2-amino-&bgr;-D-glucopyranose (glucosamine) glycosidically linked to an cyclic aminoalkyl (aglycon) group. The invention further provides methods for inducing an immune response using the compounds of the present invention in the presence or absence of an antigen. In addition, methods for treating disease with the compounds of the present invention with or without an antigen are also provided in this invention.
    Type: Grant
    Filed: February 4, 2002
    Date of Patent: February 25, 2003
    Assignee: Corixa Corporation
    Inventors: David A. Johnson, Jory R. Baldridge, C. Gregory Sowell, Christopher W. Cluff