Abstract: The disclosed methods are generally directed to preventing, treating, suppressing, controlling or otherwise mitigating side effects of T-cell therapy, the T-cell therapy designed to accelerate immune reconstitution, induce a graft-versus-malignancy effect, and/or target tumor cells. In some embodiments, the present disclosure provides expression vectors including a first expression control sequence operably linked to a first nucleic acid sequence, the first nucleic acid sequence encoding a shRNA to knockdown hypoxanthine-guanine phosphoribosyl transferase.

Abstract: A fluid atomizer and methods of atomizing fluids are disclosed. The fluid atomizer may comprise an inner member and one or more outer members. The inner member defines an interior conduit for providing a first-fluid flowpath from a supply end of the atomizer to a discharge end of the atomizer along a central axis. The one or more outer members are positioned radially outward of the inner member from the central axis. The inner and outer members define a second-fluid flowpath extending from a second-fluid supply conduit to a second-fluid discharge plenum. The second-fluid flowpath comprises a tangential conduit spiraling along the axis from the second-fluid supply conduit to a terminal end; an annulus downstream from and in fluid communication with the tangential conduit; and a second-fluid discharge plenum downstream from and in fluid communication with the annulus.

Abstract: Various embodiments include gas turbine seals and methods of forming such seals. In some cases, a turbine includes: a first arcuate component adjacent to a second arcuate component, each arcuate component including a slot including one or more slot segments located in an end face and a seal assembly disposed in the slot. The seal assembly including a plurality of seal segments forming at least one T-junction where a first seal segment intersects a second seal segment and at least one shim seal. The plurality of seal segments define at least one chute gap. The at least one shim seal disposed in a slot proximate the at least one T-junction of the plurality of seal segments. The at least one shim seal positioned on a sidewall of the second seal segment and extending a partial length of the sidewall. The at least one shim seal seals the at least one chute gap to prevent a flow therethrough of a gas turbine hot gas path flow.

Abstract: A fluid atomizer and methods of atomizing fluids are disclosed. The fluid atomizer may comprise an inner member and one or more outer members. The inner member defines an interior conduit for providing a first-fluid flowpath from a supply end of the atomizer to a discharge end of the atomizer along a central axis. The one or more outer members are positioned radially outward of the inner member from the central axis. The inner and outer members define a second-fluid flowpath extending from a second-fluid supply conduit to a second-fluid discharge plenum. The second-fluid flowpath comprises a tangential conduit spiraling along the axis from the second-fluid supply conduit to a terminal end; an annulus downstream from and in fluid communication with the tangential conduit; and a second-fluid discharge plenum downstream from and in fluid communication with the annulus.

Abstract: An adhesive strip that could be used for securing oral or nasal airway tubes, such as endotracheal tubes or laryngeal mask airways. The adhesive strip has an elongated shape and is coated on one side with an adhesive material. At each terminal end of the adhesive strip, there is a non-adhesive tab that is free of the adhesive material. The non-adhesive tabs facilitate removal of the adhesive strip off the release liner and/or off the patient's skin. The adhesive strip can be used by adhering onto the patient's face and wrapping it around the airway tube to secure the airway tube.

Abstract: An adhesive strip that could be used for securing oral or nasal airway tubes, such as endotracheal tubes or laryngeal mask airways. The adhesive strip has an elongated shape and is coated on one side with an adhesive material. At each terminal end of the adhesive strip, there is a non-adhesive tab that is free of the adhesive material. The non-adhesive tabs facilitate removal of the adhesive strip off the release liner and/or off the patient's skin. The adhesive strip can be used by adhering onto the patient's face and wrapping it around the airway tube to secure the airway tube.

Abstract: A surgical device includes a light source and an illumination unit having a lighthead that is connected to a mount by one or more support arms which are pivotally connected through joint units. The mount is provided for mounting the illumination unit to a supporting structure. The light source is disposed remotely from the lighthead, in particular not mounted on the lighthead, and is coupled to the lighthead by light conductors. In addition, a lighthead for a surgical light device is disclosed, including an optical connector that is configured to be connectable to a light conductor which is connected to a light source.

Abstract: System and methods are described for distributing artifacts in a cloud computing environment. Processing includes receiving an artifact at an upstream computing system in a network of computing systems, the artifact including a file of a continuous integration (CI) process, dividing the artifact into chunks, storing the chunks into a shared storage of the upstream computing system accessible by downstream computing systems of the network, determining downstream computing systems in the network to receive the artifact, receiving a request from one of the downstream computing systems for a chunk of the artifact; and providing the chunk to the downstream computing system from the shared storage.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for speech recognition using complex linear projection are disclosed. In one aspect, a method includes the actions of receiving audio data corresponding to an utterance. The method further includes generating frequency domain data using the audio data. The method further includes processing the frequency domain data using complex linear projection. The method further includes providing the processed frequency domain data to a neural network trained as an acoustic model. The method further includes generating a transcription for the utterance that is determined based at least on output that the neural network provides in response to receiving the processed frequency domain data.

Abstract: System and methods are described for distributing artifacts in a cloud computing environment. Processing includes receiving an artifact at an upstream computing system in a network of computing systems, the artifact including a file of a continuous integration (CI) process, dividing the artifact into chunks, storing the chunks into a shared storage of the upstream computing system accessible by downstream computing systems of the network, determining downstream computing systems in the network to receive the artifact, receiving a request from one of the downstream computing systems for a chunk of the artifact; and providing the chunk to the downstream computing system from the shared storage.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for speech recognition using complex linear projection are disclosed. In one aspect, a method includes the actions of receiving audio data corresponding to an utterance. The method further includes generating frequency domain data using the audio data. The method further includes processing the frequency domain data using complex linear projection. The method further includes providing the processed frequency domain data to a neural network trained as an acoustic model. The method further includes generating a transcription for the utterance that is determined based at least on output that the neural network provides in response to receiving the processed frequency domain data.

Abstract: A fluid atomizer and methods of atomizing fluids are disclosed. The fluid atomizer may comprise an inner member and one or more outer members. The inner member defines an interior conduit for providing a first-fluid flowpath from a supply end of the atomizer to a discharge end of the atomizer along a central axis. The one or more outer members are positioned radially outward of the inner member from the central axis. The inner and outer members define a second-fluid flowpath extending from a second-fluid supply conduit to a second-fluid discharge plenum. The second-fluid flowpath comprises a tangential conduit spiraling along the axis from the second-fluid supply conduit to a terminal end; an annulus downstream from and in fluid communication with the tangential conduit; and a second-fluid discharge plenum downstream from and in fluid communication with the annulus.

Abstract: The disclosed methods are generally directed to preventing, treating, suppressing, controlling or otherwise mitigating side effects of T-cell therapy, the T-cell therapy designed to accelerate immune reconstitution, induce a GVM effect, and/or target tumor cells.

Abstract: A flexible seal is used to seal between two adjacent gas turbine components. The flexible seal includes at least one metal ply having a forward end, an aft end axially separated from the forward end, and an intermediate portion between the forward end and the aft end. The intermediate portion defines a continuous curve in the circumferential direction, such that the aft end is circumferentially, and optionally radially, offset from the forward end. A plurality of relief cuts is defined through the at least one metal ply between the forward end and the aft end to increase flexibility and improve sealing in seal slots that are radially offset from one another.

Abstract: The disclosed methods are generally directed to preventing, treating, suppressing, controlling or otherwise mitigating side effects of T-cell therapy, the T-cell therapy designed to accelerate immune reconstitution, induce a GVM effect, and/or target tumor cells.

Abstract: Provided is a computer implemented method of authorizing transactions in a blockchain network of participant systems including a first system that sends transaction data to a second system that generates a notary request including the transaction data, at least one notary system and at least one witness system. The method includes the notary system: accepting the notary request from the second system; transmitting the transaction data to the witness systems; determining a subset of responsive witness systems; determining that a required number of affirmative responses has been received from the responsive witness systems; generating a block based on the transaction data; and publishing the block to a ledger of the blockchain network.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for speech recognition using complex linear projection are disclosed. In one aspect, a method includes the actions of receiving audio data corresponding to an utterance. The method further includes generating frequency domain data using the audio data. The method further includes processing the frequency domain data using complex linear projection. The method further includes providing the processed frequency domain data to a neural network trained as an acoustic model. The method further includes generating a transcription for the utterance that is determined based at least on output that the neural network provides in response to receiving the processed frequency domain data.

Abstract: In general, the subject matter described in this disclosure can be embodied in methods, systems, and program products for indicating a reference song. A computing device stores reference song characterization data that identifies a plurality of audio characteristics for each reference song in a plurality of reference songs. The computing device receives digital audio data that represents audio recorded by a microphone, converts the digital audio data from time-domain format into frequency-domain format, and uses the digital audio data in the frequency-domain format in a music-characterization process. In response to determining that characterization values for the digital audio data are most relevant to characterization values for a particular reference song, the computing device outputs an indication of the particular reference song.

Abstract: In general, the subject matter described in this disclosure can be embodied in methods, systems, and program products. A computing device stores reference song characterization data and receives digital audio data. The computing device determines whether the digital audio data represents music and then performs a different process to recognize that the digital audio data represents a particular reference song. The computing device then outputs an indication of the particular reference song.

Abstract: An adhesive strip that could be used for securing oral or nasal airway tubes, such as endotracheal tubes or laryngeal mask airways. The adhesive strip has an elongated shape and is coated on one side with an adhesive material. At each terminal end of the adhesive strip, there is a non-adhesive tab that is free of the adhesive material. The non-adhesive tabs facilitate removal of the adhesive strip off the release liner and/or off the patient's skin. The adhesive strip can be used by adhering onto the patient's face and wrapping it around the airway tube to secure the airway tube.