Abstract: Systems and methods are directed to a pull-through winding method, and a manufacturing fixture, or mandrel, that guides the layup of material in the pull-through winding method, for fabrication of a three-dimensional load bearing structure. These systems and methods allow fibers of material of the 3D load bearing structure to be pulled as straight as possible during winding, and maintained as straight as possible during curing, to take full advantage of properties associated with the fiber or filament-based materials used in these structures, including, for example, carbon fiber material. The manufacturing fixture includes a plurality of pull-through slots at end portions thereof, that provide for the pulling of the fiber-based material, and the application and maintenance of tension in the material that maintains the alignment of the fibers as the material is wound, cured and hardened.

Abstract: Coronavirus S ectodomain trimers stabilized in a prefusion conformation, nucleic acid molecules and vectors encoding these proteins, and methods of their use and production are disclosed. In several embodiments, the coronavirus S ectodomain trimers and/or nucleic acid molecules can be used to generate an immune response to coronavirus in a subject. In additional embodiments, the therapeutically effective amount of the coronavirus S ectodomain trimers and/or nucleic acid molecules can be administered to a subject in a method of treating or preventing coronavirus infection.

Abstract: Systems and methods are presented for efficient cross-fading of compressed domain information streams on a user/client device. Exemplary systems may provide cross-fade between AAC/Enhanced AAC Plus information streams, between MP3 information streams, or between information streams of unmatched formats. These systems are distinguished in that cross-fade is directly applied to compressed bitstreams so a single decode operation is performed on the resulting bitstream. Thus, a set of frames from each input stream associated with the time interval in which a cross fade is decoded, and combined and recoded with a cross fade or other effect now in the compressed bitstream. Once sent through the client device's decoder, the user hears the transitional effect. The only input data that is decoded and processed is that associated with the portion of each stream used the crossfade, blend or other interstitial, and thus the vast majority of input streams are left compressed.

Abstract: A method, preferably including: sampling inputs, determining aircraft conditions, and/or acting based on the aircraft conditions. A method, preferably including: sampling inputs, determining input reliability, determining guidance, and/or controlling aircraft operation. A method, preferably including: operating the vehicle, planning for contingencies, detecting undesired flight conditions, and/or reacting to undesired flight conditions. A system, preferably an aircraft such as a rotorcraft, configured to implement the method.

Abstract: A resin including up to 99.99 weight percent (wt. %) of a first polyolefin grafted with a functional group selected from an ethylenically unsaturated carboxylic acid, a carboxylic acid anhydride, an ester functional group or a combination thereof; and 0.01 to 3.0 wt. % of a tin oxide-based catalyst, where the resin includes 0.2 wt. % to 1.5 wt. % of the functional group from the first polyolefin, the wt. % based on a total weight of the resin. The first polyolefin can be selected from a polyethylene, a polypropylene, an ethylene/alpha-olefin copolymer, a propylene/alpha-olefin copolymer and combinations thereof. The tin oxide-based catalyst can be selected from dibutyltin oxide, dioctyltin oxide and combinations thereof. The resin can be used in a multilayer structure, where a Layer A comprises the resin and a Layer B comprises a polyester, where a first major surface of Layer A is in adhering contact with the second major surface of Layer B.

Abstract: Ultrasound imaging is a non-invasive, non-radioactive, and low cost technology for diagnosis and identification of implantable medical devices in real time. Developing new ultrasound activated coatings is important to broaden the utility of in vivo marking by ultrasound imaging. Ultrasound responsive macro-phase segregated micro-composite thin films were developed to be coated on medical devices composed of multiple materials and with multiple shapes and varying surface area. The macro-phase segregated films having silica micro-shells in polycyanoacrylate produces strong color Doppler signals with the use of a standard clinical ultrasound transducer. Electron microscopy showed a macro-phase separation during slow curing of the cyanoacrylate adhesive, as air-filled silica micro-shells were driven to the surface of the film. The air sealed in the hollow space of the silica shells acted as an ultrasound contrast agent and echo decorrelation of air exposed to ultrasound waves produces color Doppler signals.

Abstract: Systems, methods and apparatus for generating music recommendations based on combining song and user influencers with channel rule characterizations are presented. Such systems and methods output a playlist, which may be delivered as an information stream of audio on a user or client device, such as a telephone or smartphone, tablet, computer or MP3 player, or any consumer device with audio play capabilities. The playlist may comprise various individual audio clips of one genre or type, such as songs, or of multiple types, such as music, talk, sports and comedy. The individual audio clips may be ordered by a sequencer, which, using large amounts of data, generates both (i) user independent and (i) user dependent influencer weightings for each clip, and then combines all of such influencer weightings into a combined play weighting W for a given audio clip, for a given user.

Abstract: An autonomous vehicle is configured to estimate a change in direction of a vehicle that is on a roadway and is proximate to the autonomous vehicle. The autonomous vehicle has a mechanical system, one or more sensors that generate one or more sensor signals, and a computing system in communication with the mechanical system and the one or more sensors. The autonomous vehicle is configured to detect an imminent lane change by another vehicle based on at least one of a computed angle between a wheel of the other vehicle and a longitudinal direction of travel of the other vehicle, a degree of misalignment between the wheel of the other vehicle and a body of the other vehicle, and/or an eccentricity of the wheel of the other vehicle. The mechanical system of the autonomous vehicle is controlled by the computing system based upon the detected imminent lane change.

Abstract: A method for generating and provisioning payment credentials to a mobile device lacking a secure element includes: generating a card profile associated with a payment account, wherein the card profile includes at least payment credentials corresponding to the associated payment account and a profile identifier; provisioning, to a mobile device lacking a secure element, the generated card profile; receiving, from the mobile device, a key request, wherein the key request includes at least a mobile identification number (PIN) and the profile identifier; using the mobile PIN; generating a single use key, wherein the single use key includes at least the profile identifier, an application transaction counter, and a generating key for use in generating a payment cryptogram valid for a single financial transaction; and transmitting the generated single use key to the mobile device.

Abstract: The present invention relates to a fluid flow device. The device includes an elongate body having a proximal end, a distal end, and a length therebetween, at least one source fluid inflow port, at least one waste fluid outflow port, at least one well inlet port positioned at the distal end of the elongate body, at least one well outlet port positioned at the distal end of the elongate body, at least one conduit connecting the at least one source fluid inflow port to the at least one well inlet port, and at least one conduit connecting the at least one waste fluid outflow port to the at least one well outlet port.

Abstract: Chromatography column components are described. One component, a chromatography plug, can include a body, the body including: a first surface; a second surface opposing the first surface; a passage through the body extending from an opening in the first surface to an opening in the second surface; and a circumferential surface extending from the first surface to the second surface; a plurality of ridges, located on the first surface, wherein each of the plurality of ridges having a first end and an opposed second end, and the first end of each of the plurality of ridges being closer to one another than the second ends of each of the plurality of ridges. In some instances, a bridge can be located between the first ends, the bridge extending into the body. A porous partition can be located on or in the plug.

Abstract: A system and method for generating and provisioning payment credentials to a mobile device lacking a secure element includes receiving and storing by the mobile device a card profile from a remote system. The card profile may include payment credentials corresponding to a payment account and a profile identifier. The mobile device may receive a mobile personal identification number (PIN) input by a user of the mobile device and transmit a key request to the remote system. The mobile device may receive a single use key which may include an application transaction counter and a generating key from the remote system. The mobile device may generate a payment cryptogram valid for a single financial transaction based on the received single use key and the mobile PIN and transmit the payment credentials and the generated payment cryptogram to a point-of-sale terminal for use in a financial transaction.

Abstract: In exemplary embodiments of the present invention systems and methods are provided to implement and facilitate cross-fading, interstitials and other effects/processing of two or more media elements in a personalized media delivery service so that each client or user has a consistent high quality experience. The effects or crossfade processing can occur on the broadcast, publisher or server-side, but can still be personalized to a specific user, thus still allowing a personalized experience for each individual user, in a manner where the processing burden is minimized on the downstream side or client device. This approach enables a consistent user experience, independent of client device capabilities, both static and dynamic.

Abstract: The techniques disclosed herein analyze a garment design to create, verify, and package technical specifications usable by a manufacturer to produce a garment. Computer vision technologies are applied to an image of the garment to identify fabrics and other materials, notions such as zippers, buttons, drawstrings, etc., and individual panels that will be cut and sewn together to produce the garment. In some configurations, the identified aspects of the garment are analyzed for inconsistencies, omissions, or other errors. A designer of the garment may be prompted to resolve any errors. The confirmed specifications are then exported to a tech pack that conforms to the standards of a manufacturer, including a bill of materials, a list of panels to be cut, and annotations confirming the intent of the designer. A clothing manufacturer may then use the tech pack to configure machines to produce the garment.

Abstract: Embodiments for dynamic bandwidth allocation in cloud network switches in a cloud computing environment are provided. Quality of service (QoS) policies may be dynamically changed in one or more cloud network switches based on dynamically estimating expected traffic demands for each of a plurality of traffic classes, wherein bandwidth is dynamically allocated among queues based on changing the QoS policies.

Abstract: The present invention provides binding molecules (e.g. antibodies or antigen-binding fragments thereof) against FR? and related antibody-drug conjugates, along with pharmaceutical compositions and kits comprising the same. Methods for use of said binding molecules and related antibody-drug conjugates in the treatment of cancer are also provided.

Abstract: Systems and methods are presented for cross-fading (or other multiple clip processing) of information streams on a user or client device, such as a telephone, tablet, computer or MP3 player, or any consumer device with audio playback. Multiple clip processing can be accomplished at a client end according to directions sent from a service provider that specify a combination of (i) the clips involved; (ii) the device on which the cross-fade or other processing is to occur and its parameters; and (iii) the service provider system. For example, a consumer device with only one decoder, can utilize that decoder (typically hardware) to decompress one or more elements that are involved in a cross-fade at faster than real time, thus pre-fetching the next element(s) to be played in the cross-fade at the end of the currently being played element.

Abstract: An autonomous vehicle is configured to estimate a change in direction of a vehicle that is on a roadway and is proximate to the autonomous vehicle. The autonomous vehicle has a mechanical system, one or more sensors that generate one or more sensor signals, and a computing system in communication with the mechanical system and the one or more sensors. The autonomous vehicle is configured to detect an imminent lane change by another vehicle based on at least one of a computed angle between a wheel of the other vehicle and a longitudinal direction of travel of the other vehicle, a degree of misalignment between the wheel of the other vehicle and a body of the other vehicle, and/or an eccentricity of the wheel of the other vehicle. The mechanical system of the autonomous vehicle is controlled by the computing system based upon the detected imminent lane change.

Abstract: Embodiments for dynamic bandwidth allocation in cloud network switches in a cloud computing environment are provided. Quality of service (QoS) policies may be dynamically changed in one or more cloud network switches based on dynamically estimating expected traffic demands for each of a plurality of traffic classes, wherein bandwidth is dynamically allocated among queues based on changing the QoS policies.

Abstract: An autonomous vehicle is described, wherein the autonomous vehicle is configured to estimate a change in direction of a vehicle that is on a roadway and is proximate to the autonomous vehicle. The autonomous vehicle has a mechanical system, one or more sensors that generate one or more sensor signals, and a computing system in communication with the mechanical system and the one or more sensors. The autonomous vehicle is configured to detect an imminent lane change by another vehicle based on at least one of a computed angle between a wheel of the other vehicle and a longitudinal direction of travel of the other vehicle, a degree of misalignment between the wheel of the other vehicle and a body of the other vehicle, and/or an eccentricity of the wheel of the other vehicle. The mechanical system of the autonomous vehicle is controlled by the computing system based upon the detected imminent lane change.